Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors. - Wikidata - awgldk - TriplyDB

Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors.

Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors.

http://www.wikidata.org/entity/Q42431117

about

Salinomycin as a drug for targeting human cancer stem cells Salinomycin: a novel anti-cancer agent with known anti-coccidial activities GPR39 is coupled to TMEM16A in intestinal fibroblast-like cells Salinomycin potentiates the cytotoxic effects of TRAIL on glioblastoma cell lines A late-stage intermediate in salinomycin biosynthesis is revealed by specific mutation in the biosynthetic gene cluster.Interstitial cells: regulators of smooth muscle function.Adjuvant treatment of GIST: patient selection and treatment strategies.High-grade KIT-negative sarcoma of the small bowel in a patient with chronic myeloid leukemia receiving long-term tyrosine kinase inhibitors.Adjuvant therapy for high-risk gastrointestinal stromal tumour: considerations for optimal management.Dystrophin is a tumor suppressor in human cancers with myogenic programs.Inactivation of Patched1 in mice leads to development of gastrointestinal stromal-like tumors that express Pdgfrα but not kit.Tyrosine kinase inhibitors in the treatment of unresectable or metastatic gastrointestinal stromal tumors.Expression and significance of neuroligins in myenteric cells of Cajal in Hirschsprung's disease.Membrane-to-nucleus signaling links insulin-like growth factor-1- and stem cell factor-activated pathways.Generalized neuromuscular hypoplasia, reduced smooth muscle myosin and altered gut motility in the klotho model of premature aging Primary analysis and screening of microRNAs in gastric cancer side population cells Stem cells for murine interstitial cells of cajal suppress cellular immunity and colitis via prostaglandin E2 secretion.Ano1 as a regulator of proliferation.Targeting Disease Persistence in Gastrointestinal Stromal Tumors FAM96A is a novel pro-apoptotic tumor suppressor in gastrointestinal stromal tumors.Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1.Breast cancer stem cell selectivity of synthetic nanomolar-active salinomycin analogs Total Glucosides of Paeony Promote Intestinal Motility in Slow Transit Constipation Rats through Amelioration of Interstitial Cells of Cajal.Lower salinomycin concentration increases apoptotic detachment in high-density cancer cells.The impact of metformin and salinomycin on transforming growth factor β-induced epithelial-to-mesenchymal transition in non-small cell lung cancer cell lines Drug repurposing for gastrointestinal stromal tumor.Low amount of salinomycin greatly increases Akt activation, but reduces activated p70S6K levels Reintroduction of imatinib in GIST Global gene expression analysis of canine osteosarcoma stem cells reveals a novel role for COX-2 in tumour initiation.Characterization of interstitial Cajal progenitors cells and their changes in Hirschsprung's disease.Hedgehog pathway dysregulation contributes to the pathogenesis of human gastrointestinal stromal tumors via GLI-mediated activation of KIT expression.The management of gastrointestinal stromal tumors: a model for targeted and multidisciplinary therapy of malignancy.Clinical implication of targeting of cancer stem cells.Therapeutic targeting of c-KIT in cancer.Interstitial Cells of Cajal: Pathology, injury and repair.Controversies in the management of gastrointestinal stromal tumors.Diabetes-related dysfunction of the small intestine and the colon: focus on motility.Combined inhibition of MAP kinase and KIT signaling synergistically destabilizes ETV1 and suppresses GIST tumor growth.Enhanced autophagy is required for survival in EGFR-independent EGFR-mutant lung adenocarcinoma cells.Salinomycin: A new paradigm in cancer therapy.

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Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors.

http://www.wikidata.org/entity/Q42431117

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Kitlow stem cells cause resist ...... strointestinal stromal tumors.

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Kitlow stem cells cause resist ...... strointestinal stromal tumors.

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Kitlow stem cells cause resist ...... strointestinal stromal tumors.

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Kitlow stem cells cause resist ...... strointestinal stromal tumors.

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Kitlow stem cells cause resist ...... strointestinal stromal tumors.

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J.GASTRO.2010.05.083

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Gastroenterology

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Kitlow stem cells cause resist ...... strointestinal stromal tumors.

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Andrea Lorincz

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Brian P Rubin

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David L Young

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David T Asuzu

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Doug Redelman

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Gianrico Farrugia

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Gwen A Lomberk

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Laura N Popko

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Michael R Bardsley

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Raul A Urrutia

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P2860

Ano1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tract

Prospective identification of tumorigenic breast cancer cells

Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors

Identification of selective inhibitors of cancer stem cells by high-throughput screening

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

Development and plasticity of interstitial cells of Cajal.

Cellular pathogenesis of diabetic gastroenteropathy.

Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial.

Physiology, injury, and recovery of interstitial cells of Cajal: basic and clinical science

PDGFRA activating mutations in gastrointestinal stromal tumors.

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