Human VKORC1 mutations cause variable degrees of 4-hydroxycoumarin resistance and affect putative warfarin binding interfaces.
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Structural Modeling Insights into Human VKORC1 PhenotypesVKORC1 and VKORC1L1: Why do Vertebrates Have Two Vitamin K 2,3-Epoxide Reductases?Membrane Cholesterol Modulates Superwarfarin Toxicity.Zebrafish vitamin K epoxide reductases: expression in vivo, along extracellular matrix mineralization and under phylloquinone and warfarin in vitro exposure.Frequency of Common VKORC1 Polymorphisms and Their Impact on Warfarin Dose Requirement in Pakistani Population.Warfarin traps human vitamin K epoxide reductase in an intermediate state during electron transfer.Genes affecting warfarin response-interactive or additive?Evidence of a target resistance to antivitamin K rodenticides in the roof rat Rattus rattus: identification and characterisation of a novel Y25F mutation in the Vkorc1 gene.Warfarin and vitamin K compete for binding to Phe55 in human VKOR.Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase.Study of the efficiency of anticoagulant rodenticides to control Mus musculus domesticus introgressed with Mus spretus Vkorc1.
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P2860
Human VKORC1 mutations cause variable degrees of 4-hydroxycoumarin resistance and affect putative warfarin binding interfaces.
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2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
Human VKORC1 mutations cause v ...... e warfarin binding interfaces.
@en
Human VKORC1 mutations cause v ...... e warfarin binding interfaces.
@nl
type
label
Human VKORC1 mutations cause v ...... e warfarin binding interfaces.
@en
Human VKORC1 mutations cause v ...... e warfarin binding interfaces.
@nl
prefLabel
Human VKORC1 mutations cause v ...... e warfarin binding interfaces.
@en
Human VKORC1 mutations cause v ...... e warfarin binding interfaces.
@nl
P2093
P1433
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Human VKORC1 mutations cause v ...... ve warfarin binding interfaces
@en
P2093
Clemens R Müller
Johannes Oldenburg
Katrin J Czogalla
Matthias Watzka
Philipp Westhofen
P304
P356
10.1182/BLOOD-2013-05-501692
P407
P577
2013-08-27T00:00:00Z