cAMP signaling regulates platelet myosin light chain (MLC) phosphorylation and shape change through targeting the RhoA-Rho kinase-MLC phosphatase signaling pathway.
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Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDSCompressive stress induces dephosphorylation of the myosin regulatory light chain via RhoA phosphorylation by the adenylyl cyclase/protein kinase A signaling pathway.Multiplexed phosphospecific flow cytometry enables large-scale signaling profiling and drug screening in blood platelets.Dissociation of SHP-1 from spinophilin during platelet activation exposes an inhibitory binding site for protein phosphatase-1 (PP1)Cancer cell-derived 12(S)-HETE signals via 12-HETE receptor, RHO, ROCK and MLC2 to induce lymph endothelial barrier breaching.Platelet myosin light chain phosphatase: keeping it together.The control of blood platelets by cAMP signalling.Prostacyclin reverses platelet stress fibre formation causing platelet aggregate instability.Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B.cGMP signaling inhibits platelet shape change through regulation of the RhoA-Rho Kinase-MLC phosphatase signaling pathway.Regulation of inflammation by lipid mediators in oral diseases.New Concepts and Mechanisms of Platelet Activation Signaling.Role of myosin light chain and myosin light chain kinase in advanced glycation end product-induced endothelial hyperpermeability in vitro and in vivo.Oxidized LDL activates blood platelets through CD36/NOX2-mediated inhibition of the cGMP/protein kinase G signaling cascade.Regulation of cAMP Intracellular Levels in Human Platelets Stimulated by 2-Arachidonoylglycerol.Targeting of type I protein kinase A to lipid rafts is required for platelet inhibition by the 3',5'-cyclic adenosine monophosphate-signaling pathway.Viral activation of stress-regulated Rho-GTPase signaling pathway disrupts sites of mRNA degradation to influence cellular gene expression.The Spatiotemporal Regulation of cAMP Signaling in Blood Platelets-Old Friends and New PlayersPPARγ agonists negatively regulate αIIbβ3 integrin outside-in signaling and platelet function through up-regulation of protein kinase A activity.RXR Ligands Negatively Regulate Thrombosis and Hemostasis.cAMP-dependent regulation of RhoA/Rho-kinase attenuates detrusor overactivity in a novel mouse experimental model.The role and importance of cofilin in human sperm capacitation and the acrosome reaction.Reversal of stress fibre formation by Nitric Oxide mediated RhoA inhibition leads to reduction in the height of preformed thrombi.Anagrelide platelet-lowering effect is due to inhibition of both megakaryocyte maturation and proplatelet formation: insight into potential mechanisms.Energy and motion: AMP-activated protein kinase α1 and its role in platelet activation.Image-guided chemotherapy with specifically tuned blood brain barrier permeability in glioma margins.
P2860
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P2860
cAMP signaling regulates platelet myosin light chain (MLC) phosphorylation and shape change through targeting the RhoA-Rho kinase-MLC phosphatase signaling pathway.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
cAMP signaling regulates plate ...... phosphatase signaling pathway.
@en
cAMP signaling regulates platelet myosin light chain
@nl
type
label
cAMP signaling regulates plate ...... phosphatase signaling pathway.
@en
cAMP signaling regulates platelet myosin light chain
@nl
prefLabel
cAMP signaling regulates plate ...... phosphatase signaling pathway.
@en
cAMP signaling regulates platelet myosin light chain
@nl
P2093
P1433
P1476
cAMP signaling regulates plate ...... phosphatase signaling pathway.
@en
P2093
Ahmed Aburima
Katie S Wraith
Khalid M Naseem
Robert Law
Simbarashe Magwenzi
Zaher Raslan
P304
P356
10.1182/BLOOD-2013-03-487850
P407
P577
2013-10-07T00:00:00Z