HCT116 cells deficient in p21(Waf1) are hypersensitive to tyrosine kinase inhibitors and adriamycin through a mechanism unrelated to p21 and dependent on p53.
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RITA displays anti-tumor activity in medulloblastomas independent of TP53 status.Serum-nutrient starvation induces cell death mediated by Bax and Puma that is counteracted by p21 and unmasked by Bcl-x(L) inhibition.Constitutive p53 heightens mitochondrial apoptotic priming and favors cell death induction by BH3 mimetic inhibitors of BCL-xLSpontaneous γH2AX Foci in Human Solid Tumor-Derived Cell Lines in Relation to p21WAF1 and WIP1 Expression.Isolation and characterization of erlotinib-resistant human non-small cell lung cancer A549 cells.Influence of selected anti-cancer drugs on the induction of DNA double-strand breaks and changes in gene expression in human hepatoma HepG2 cells.p21 does not protect cancer cells from apoptosis induced by nongenotoxic p53 activation.
P2860
Q33709483-D27154D0-1B5A-418D-8DFC-F6646790D10FQ34009416-A1D5476E-F245-4AF8-A2E6-1EAFAFF6E6ABQ38796648-825494E2-110B-4064-A815-A100780E3ACFQ38871254-0D5FBEFD-3E72-440C-B8C3-B3D04C6405A1Q42146311-29377964-5E5E-447F-8858-E3E8B4DF627BQ51332973-B12C2F88-F30A-4726-B7CC-B373E5BBAFF4Q54647670-100B8E7D-4EF3-42F7-8997-FDD01636238D
P2860
HCT116 cells deficient in p21(Waf1) are hypersensitive to tyrosine kinase inhibitors and adriamycin through a mechanism unrelated to p21 and dependent on p53.
description
2009 nî lūn-bûn
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2009年の論文
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2009年論文
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2009年論文
@zh-hant
2009年論文
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2009年論文
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2009年論文
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2009年论文
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2009年论文
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name
HCT116 cells deficient in p21
@nl
HCT116 cells deficient in p21( ...... d to p21 and dependent on p53.
@en
type
label
HCT116 cells deficient in p21
@nl
HCT116 cells deficient in p21( ...... d to p21 and dependent on p53.
@en
prefLabel
HCT116 cells deficient in p21
@nl
HCT116 cells deficient in p21( ...... d to p21 and dependent on p53.
@en
P2093
P50
P1433
P1476
HCT116 cells deficient in p21( ...... d to p21 and dependent on p53.
@en
P2093
Derya Donertas
M Dolores Delgado
Paolo Dotto
Rosa Blanco
P304
P356
10.1016/J.DNAREP.2008.12.001
P577
2009-01-15T00:00:00Z