Interferon alfa down-regulates collagen gene transcription and suppresses experimental hepatic fibrosis in mice. - Wikidata - awgldk - TriplyDB

Interferon alfa down-regulates collagen gene transcription and suppresses experimental hepatic fibrosis in mice.

Interferon alfa down-regulates collagen gene transcription and suppresses experimental hepatic fibrosis in mice.

http://www.wikidata.org/entity/Q42450667

about

Hepatic stellate cells: protean, multifunctional, and enigmatic cells of the liver Interferon augments the anti-fibrotic activity of an angiotensin-converting enzyme inhibitor in patients with refractory chronic hepatitis C.Fibrogenesis and Carcinogenesis in Nonalcoholic Steatohepatitis (NASH): Involvement of Matrix Metalloproteinases (MMPs) and Tissue Inhibitors of Metalloproteinase (TIMPs).A novel small compound that promotes nuclear translocation of YB-1 ameliorates experimental hepatic fibrosis in mice.Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis.Chromatin dynamics of gene activation and repression in response to interferon alpha (IFN(alpha)) reveal new roles for phosphorylated and unphosphorylated forms of the transcription factor STAT2 Hepatic inflammation and fibrosis: functional links and key pathways.Type I interferons and their therapeutic role in Th2-regulated inflammatory disorders.Smad3 as a mediator of the fibrotic response.Myocardin-Related Transcription Factor A Epigenetically Regulates Renal Fibrosis in Diabetic Nephropathy.Cytokines and STATs in Liver Fibrosis.A Combination of Mitochondrial Oxidative Stress and Excess Fat/Calorie Intake Accelerates Steatohepatitis by Enhancing Hepatic CC Chemokine Production in Mice.Emerging insights into Transforming growth factor beta Smad signal in hepatic fibrogenesis.Effect of Antiviral Therapy on Serum Activity of Angiotensin Converting Enzyme in Patients with Chronic Hepatitis C.Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function?Beneficial drugs for liver diseases.Bioconjugation of oligonucleotides for treating liver fibrosis.Innate immunity and alcoholic liver fibrosis.Systematic review: hepatic fibrosis - regression with therapy.Activation of natural killer cells inhibits liver fibrosis: a novel strategy to treat liver fibrosis.Advances in antifibrotic therapy.Reduction in Hepatic Inflammation Is Associated With Less Fibrosis Progression and Fewer Clinical Outcomes in Advanced Hepatitis C.Collagen-binding vascular endothelial growth factor attenuates CCl4-induced liver fibrosis in mice.Translating an understanding of the pathogenesis of hepatic fibrosis to novel therapies Hydrolysable tannins of tropical almond show antifibrotic effects in TGF-β1-induced hepatic stellate cells.IFN-γ deficiency attenuates hepatic inflammation and fibrosis in a steatohepatitis model induced by a methionine- and choline-deficient high-fat diet.Stromal and immune cells in gut fibrosis: the myofibroblast and the scarface.Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation.Increased incidence of cytomegalovirus coinfection in HCV-infected patients with late liver fibrosis is associated with dysregulation of JAK-STAT pathway.Safety, Tolerability, and Preliminary Efficacy of the Anti-Fibrotic Small Molecule PRI-724, a CBP/β-Catenin Inhibitor, in Patients with Hepatitis C Virus-related Cirrhosis: A Single-Center, Open-Label, Dose Escalation Phase 1 Trial.Interferon type I and type II responses in an Atlantic salmon (Salmo salar) SHK-1 cell line by the salmon TRAITS/SGP microarray.Clinical trial: interferon alpha-2b continuous long-term therapy vs. repeated 24-week cycles for re-treating chronic hepatitis C.Zinc mediated hepatic stellate cell collagen synthesis reduction through TGF-β signaling pathway inhibition.Effect of natural interferon α on proliferation and apoptosis of hepatic stellate cells The role of chemokines in acute liver injury.Treatment failure may lead to accelerated fibrosis progression in patients with chronic hepatitis C.Transcriptional regulation of human alpha1(I) procollagen gene in dermal fibroblasts.Silencing a killer among us: ethanol impairs immune surveillance of activated stellate cells by natural killer cells.Evolution of hepatic fibrosis research.CD4+CD25+Foxp3+ regulatory T cells contribute in liver fibrosis improvement with interferon alpha.

P2860

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P2860

Interferon alfa down-regulates collagen gene transcription and suppresses experimental hepatic fibrosis in mice.

http://www.wikidata.org/entity/Q42450667

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年论文

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name

Interferon alfa down-regulates ...... ntal hepatic fibrosis in mice.

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Interferon alfa down-regulates ...... ntal hepatic fibrosis in mice.

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type

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Interferon alfa down-regulates ...... ntal hepatic fibrosis in mice.

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Interferon alfa down-regulates ...... ntal hepatic fibrosis in mice.

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Interferon alfa down-regulates ...... ntal hepatic fibrosis in mice.

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Interferon alfa down-regulates ...... ntal hepatic fibrosis in mice.

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Interferon alfa down-regulates ...... ntal hepatic fibrosis in mice.

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Atsuhito Nakao

http://www.w3.org/2001/XMLSchema#string

Benoit de Crombrugghe

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Fumiaki Shirasaki

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Hiroshi Yamauchi

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Isao Okazaki

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Kazuhiko Takehara

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Kazuo Ikeda

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Kiyoshi Higashi

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Kota Sugiyama

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Mitsukiyo Fujii

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P2860

Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction

Primary structural repeats in human and in murine gamma-interferon.

The Extracellular Matrix of the Liver

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890-899

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10.1002/HEP.1840380415

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38

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2003-10-01T00:00:00Z

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14512876

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