SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase
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Myelin suppresses axon regeneration by PIR-B/SHP-mediated inhibition of Trk activityRepression of SHP-1 expression by p53 leads to trkA tyrosine phosphorylation and suppression of breast cancer cell proliferationTetraspanin CD37 directly mediates transduction of survival and apoptotic signalsNeuroblastoma tyrosine kinase signaling networks involve FYN and LYN in endosomes and lipid raftsMicroarray Analysis Reveals Increased Transcriptional Repression and Reduced Metabolic Activity but Not Major Changes in the Core Apoptotic Machinery during Maturation of Sympathetic Neurons.Adjunctive dexamethasone affects the expression of genes related to inflammation, neurogenesis and apoptosis in infant rat pneumococcal meningitisCrystal structure of human protein tyrosine phosphatase SHP-1 in the open conformationProtein-tyrosine phosphatase (PTP) wedge domain peptides: a novel approach for inhibition of PTP function and augmentation of protein-tyrosine kinase functionThe protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiationAxonal targeting of Trk receptors via transcytosis regulates sensitivity to neurotrophin responsesSputa nerve growth factor forms a preferable substitute to mouse 7S-beta nerve growth factorAnalysis of SHP-1-mediated down-regulation of the TRK-T3 oncoprotein identifies Trk-fused gene (TFG) as a novel SHP-1-interacting protein.NEAP/DUSP26 suppresses receptor tyrosine kinases and regulates neuronal development in zebrafish.Nerve growth factor (NGF) regulates activity of nuclear factor of activated T-cells (NFAT) in neurons via the phosphatidylinositol 3-kinase (PI3K)-Akt-glycogen synthase kinase 3β (GSK3β) pathwayProteomic analysis of novel targets associated with TrkA-mediated tyrosine phosphorylation signaling pathways in SK-N-MC neuroblastoma cells.Negative Regulation of Receptor Tyrosine Kinase (RTK) Signaling: A Developing FieldPromoter-specific induction of the phosphatase SHP-1 by viral infection and cytokines in CNS gliaRegulation of avoidant behaviors and pain by the anti-inflammatory tyrosine phosphatase SHP-1.The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury.Regulation of EphB2 activation and cell repulsion by feedback control of the MAPK pathway.Novel sorafenib analogues induce apoptosis through SHP-1 dependent STAT3 inactivation in human breast cancer cells.Regulation of neurotrophin receptor (Trk) signaling: suppressor of cytokine signaling 2 (SOCS2) is a new player.Nerve growth factor in diabetic retinopathy: beyond neurons.Protein-tyrosine phosphatase SHP2 contributes to GDNF neurotrophic activity through direct binding to phospho-Tyr687 in the RET receptor tyrosine kinase.c-Met signaling promotes IL-6-induced myeloma cell proliferation.SLAM-associated protein as a potential negative regulator in Trk signaling.Tyrosine phosphatase SHP-2 is a mediator of activity-dependent neuronal excitotoxicity.Imbalance of the Nerve Growth Factor and Its Precursor: Implication in Diabetic Retinopathy.TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic "Achilles heel" for the TrkAIII oncoprotein in neuroblastoma.Optimal replication of human cytomegalovirus correlates with endocytosis of glycoprotein gpUL132.Protein tyrosine phosphatase receptor type Z dephosphorylates TrkA receptors and attenuates NGF-dependent neurite outgrowth of PC12 cells.Type I interferons impair BDNF-induced cell signaling and neurotrophic activity in differentiated human SH-SY5Y neuroblastoma cells and mouse primary cortical neurons.Tyr-701 is a new regulatory site for neurotrophin receptor TrkA trafficking and function.Phosphorylation of NTRK1 at Y674/Y675 induced by TP53-dependent repression of PTPN6 expression: a potential novel prognostic marker for breast cancer.Phospho-Regulation of Soma-to-Axon Transcytosis of Neurotrophin Receptors.Lycorine inhibits the growth and metastasis of breast cancer through the blockage of STAT3 signaling pathway.
P2860
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P2860
SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase
@en
SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase
@nl
type
label
SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase
@en
SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase
@nl
prefLabel
SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase
@en
SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase
@nl
P2093
P2860
P356
P1476
SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase
@en
P2093
Benjamin G Neel
Catherine I Dubreuil
Celia Quevedo
David R Kaplan
Farid Arab Said
Freda D Miller
Gregory S Walsh
H Nicholas Marsh
Katherine Siminovitch
Marta Majdan
P2860
P304
P356
10.1083/JCB.200309036
P407
P50
P577
2003-12-01T00:00:00Z