The farnesyl transferase inhibitor R115777 (Zarnestra) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa) and Pamidronate.
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Nanoparticles for the delivery of zoledronic acid to prostate cancer cells: a comparative analysis through time lapse video-microscopy technique.Bisphosphonates for osteoporosis treatment are associated with reduced breast cancer risk.Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation.Proteomic analysis of zoledronic-acid resistant prostate cancer cells unveils novel pathways characterizing an invasive phenotype.Significance of KRAS/PAK1/Crk pathway in non-small cell lung cancer oncogenesisStathmin is involved in the cooperative effect of Zoledronic acid and gefitinib on bone homing breast cancer cells in vitro.Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells.Analysis of molecular mechanisms and anti-tumoural effects of zoledronic acid in breast cancer cells.CCN1, a candidate target for zoledronic acid treatment in breast cancer.Zoledronic acid: an unending tale for an antiresorptive agent.Myeloid-derived suppressor cells in multiple myeloma: pre-clinical research and translational opportunities.miR-29s: a family of epi-miRNAs with therapeutic implications in hematologic malignancies.Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway.Effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway.Zoledronic acid in combination with serine/threonine phosphatase inhibitors induces enhanced cytotoxicity and apoptosis in hormone-refractory prostate cancer cell lines by decreasing the activities of PP1 and PP2A.Zoledronate can promote apoptosis and inhibit the proliferation of colorectal cancer cells.Bisphosphonates and cancer: what opportunities from nanotechnology?Citrinin induces apoptosis via a mitochondria-dependent pathway and inhibition of survival signals in embryonic stem cells, and causes developmental injury in blastocysts.Zoledronate inhibits proliferation and induces apoptosis of imatinib-resistant chronic myeloid leukaemia cells.Bisphosphonate conjugation for bone specific drug targeting.
P2860
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P2860
The farnesyl transferase inhibitor R115777 (Zarnestra) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa) and Pamidronate.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
The farnesyl transferase inhib ...... acid (Zometa) and Pamidronate.
@en
The farnesyl transferase inhibitor R115777
@nl
type
label
The farnesyl transferase inhib ...... acid (Zometa) and Pamidronate.
@en
The farnesyl transferase inhibitor R115777
@nl
prefLabel
The farnesyl transferase inhib ...... acid (Zometa) and Pamidronate.
@en
The farnesyl transferase inhibitor R115777
@nl
P2093
P2860
P50
P356
P1433
P1476
The farnesyl transferase inhib ...... acid (Zometa) and Pamidronate.
@en
P2093
Alberto Abbruzzese
Anna Maria D'Alessandro
Caterina Viscomi
Gaia Giuberti
Giovanni Vitale
Monica Marra
Pierfrancesco Tassone
Pierosandro Tagliaferri
Salvatore Del Prete
Salvatore Venuta
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207814
P407
P577
2004-09-01T00:00:00Z
P5875
P6179
1010730480