Microcephalin is a new novel prognostic indicator in breast cancer associated with BRCA1 inactivation. - Wikidata - awgldk - TriplyDB

Microcephalin is a new novel prognostic indicator in breast cancer associated with BRCA1 inactivation.

Microcephalin is a new novel prognostic indicator in breast cancer associated with BRCA1 inactivation.

http://www.wikidata.org/entity/Q42474347

about

The overexpression of MCPH1 inhibits cell growth through regulating cell cycle-related proteins and activating cytochrome c-caspase 3 signaling in cervical cancer Ciliogenesis and the DNA damage response: a stressful relationship A meta-analysis of multiple matched copy number and transcriptomics data sets for inferring gene regulatory relationships.MCPH1: a window into brain development and evolution.Deregulation of microcephalin and ASPM expression are correlated with epithelial ovarian cancer progression.Primary microcephaly gene MCPH1 shows a novel molecular biomarker of human renal carcinoma and is regulated by miR-27a.Primary microcephaly gene MCPH1 shows signatures of tumor suppressors and is regulated by miR-27a in oral squamous cell carcinoma.Phosphorylation of the BRCA1 C terminus (BRCT) repeat inhibitor of hTERT (BRIT1) protein coordinates TopBP1 protein recruitment and amplifies ataxia telangiectasia-mutated and Rad3-related (ATR) Signaling A high-throughput assay to identify modifiers of premature chromosome condensation.ASPM and microcephalin expression in epithelial ovarian cancer correlates with tumour grade and survival Mcph1/Brit1 deficiency promotes genomic instability and tumor formation in a mouse model Targeted Next-Generation Sequencing Identifies a Recurrent Mutation in MCPH1 Associating with Hereditary Breast Cancer Susceptibility.Immunoprofile from tissue microarrays to stratify familial breast cancer patients BRIT1 regulates p53 stability and functions as a tumor suppressor in breast cancer.The DNA damage response molecule MCPH1 in brain development and beyond.Overexpression of MCPH1 inhibits uncontrolled cell growth by promoting cell apoptosis and arresting the cell cycle in S and G2/M phase in lung cancer cells Frequent alterations of MCPH1 and ATM are associated with primary breast carcinoma: clinical and prognostic implications.Expression of proteins involved in DNA damage response in familial and sporadic breast cancer patients.Expression of DNA Damage Response Proteins and Associations with Clinicopathologic Characteristics in Chinese Familial Breast Cancer Patients with Mutations

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Microcephalin is a new novel prognostic indicator in breast cancer associated with BRCA1 inactivation.

http://www.wikidata.org/entity/Q42474347

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Microcephalin is a new novel p ...... iated with BRCA1 inactivation.

@en

Microcephalin is a new novel p ...... iated with BRCA1 inactivation.

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Microcephalin is a new novel p ...... iated with BRCA1 inactivation.

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type

label

Microcephalin is a new novel p ...... iated with BRCA1 inactivation.

@en

Microcephalin is a new novel p ...... iated with BRCA1 inactivation.

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Microcephalin is a new novel p ...... iated with BRCA1 inactivation.

@nl

prefLabel

Microcephalin is a new novel p ...... iated with BRCA1 inactivation.

@en

Microcephalin is a new novel p ...... iated with BRCA1 inactivation.

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Microcephalin is a new novel p ...... iated with BRCA1 inactivation.

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P1433

Breast Cancer Research and Treatment

P1476

Microcephalin is a new novel p ...... iated with BRCA1 inactivation.

@en

P2093

Clare Walker

http://www.w3.org/2001/XMLSchema#string

Julie Richardson

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Rawiah Alisary

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Sandra M Bell

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P2860

Identification of microcephalin, a protein implicated in determining the size of the human brain

Microcephalin Is a DNA Damage Response Protein Involved in Regulation of CHK1 and BRCA1

Multiple tumor suppressor pathways negatively regulate telomerase

MCPH1/BRIT1 cooperates with E2F1 in the activation of checkpoint, DNA repair and apoptosis

Regulation of BRCA1 expression and its relationship to sporadic breast cancer

Establishment of a mouse model with misregulated chromosome condensation due to defective Mcph1 function

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers.

Differential regulation of centrosome integrity by DNA damage response proteins.

BRIT1 regulates early DNA damage response, chromosomal integrity, and cancer

BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice.

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Abeer M. Shaaban

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