Inhibition of endothelial nitric oxide synthase by ebselen. Prevention by thiols suggests the inactivation by ebselen of a critical thiol essential for the catalytic activity of nitric oxide synthase.
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Cerebral Small Vessel Disease: Targeting Oxidative Stress as a Novel Therapeutic Strategy?Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target EngagementIdentification of small molecules that inhibit the interaction of TEM8 with anthrax protective antigen using a FRET assay.Developing selective histone deacetylases (HDACs) inhibitors through ebselen and analogs.Essential hypertension and oxidative stress: New insightsEbselen is a potent non-competitive inhibitor of extracellular nucleoside diphosphokinaseDifferential actions of L-cysteine on responses to nitric oxide, nitroxyl anions and EDRF in the rat aortaEbselen inhibits QSOX1 enzymatic activity and suppresses invasion of pancreatic and renal cancer cell linesInhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450.Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits.Ebselen exerts antifungal activity by regulating glutathione (GSH) and reactive oxygen species (ROS) production in fungal cells.Antioxidants as potential therapeutics for lung fibrosis.Catalase and glutathione peroxidase mimics.The antihypertensive effect of cysteine.Ebselen induces reactive oxygen species (ROS)-mediated cytotoxicity in Saccharomyces cerevisiae with inhibition of glutamate dehydrogenase being a target.Possible mechanisms for induction of oxidative stress and suppression of systemic nitric oxide production caused by exposure to environmental chemicals.Glutathione peroxidase activity is neuroprotective in models of Huntington's disease.Ebselen alleviates testicular pathology in mice with Zika virus infection and prevents its sexual transmission.Synthesis of Novel Selenides Bearing Benzenesulfonamide Moieties as Carbonic Anhydrase I, II, IV, VII, and IX Inhibitors.The cysteine-reactive small molecule ebselen facilitates effective SOD1 maturation.
P2860
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P2860
Inhibition of endothelial nitric oxide synthase by ebselen. Prevention by thiols suggests the inactivation by ebselen of a critical thiol essential for the catalytic activity of nitric oxide synthase.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Inhibition of endothelial nitr ...... vity of nitric oxide synthase.
@en
Inhibition of endothelial nitr ...... vity of nitric oxide synthase.
@nl
type
label
Inhibition of endothelial nitr ...... vity of nitric oxide synthase.
@en
Inhibition of endothelial nitr ...... vity of nitric oxide synthase.
@nl
prefLabel
Inhibition of endothelial nitr ...... vity of nitric oxide synthase.
@en
Inhibition of endothelial nitr ...... vity of nitric oxide synthase.
@nl
P2093
P1476
Inhibition of endothelial nitr ...... ivity of nitric oxide synthase
@en
P2093
Gryglewski RJ
Hatchett RJ
Radziszewski W
Zembowicz A
P304
P407
P577
1993-12-01T00:00:00Z