Identification of a novel mutant transcript of laminin alpha 2 chain gene responsible for muscular dystrophy and dysmyelination in dy2J mice.
about
Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies.Form and function: the laminin family of heterotrimersGenomic structure and identification of novel mutations in usherin, the gene responsible for Usher syndrome type IIaDevelopmental and pathogenic mechanisms of basement membrane assemblyLaminin expression in adult and developing retinae: evidence of two novel CNS lamininsLaminin regulates PDGFRβ(+) cell stemness and muscle development.Distinct roles for laminin globular domains in laminin alpha1 chain mediated rescue of murine laminin alpha2 chain deficiencyBortezomib Does Not Reduce Muscular Dystrophy in the dy2J/dy2J Mouse Model of Laminin α2 Chain-Deficient Muscular DystrophyA role of dystroglycan in schwannoma cell adhesion to lamininMild congenital muscular dystrophy in two patients with an internally deleted laminin alpha2-chainIntegrins (alpha7beta1) in muscle function and survival. Disrupted expression in merosin-deficient congenital muscular dystrophyRole of laminin terminal globular domains in basement membrane assemblyGlycosylation defects: a new mechanism for muscular dystrophy?Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant micePotent pro-inflammatory and pro-fibrotic molecules, osteopontin and galectin-3, are not major disease modulators of laminin α2 chain-deficient muscular dystrophy.Laminins of the neuromuscular system.Laminins and human disease.Basement membranes: cell scaffoldings and signaling platforms.The organization of the forelimb representation of the C57BL/6 mouse motor cortex as defined by intracortical microstimulation and cytoarchitectureSchwann cell-specific ablation of laminin gamma1 causes apoptosis and prevents proliferation.Alternative splicing dysregulation secondary to skeletal muscle regeneration.Elimination of myostatin does not combat muscular dystrophy in dy mice but increases postnatal lethality.Gene transfer establishes primacy of striated vs. smooth muscle sarcoglycan complex in limb-girdle muscular dystrophy.Life or death by NFκB, Losartan promotes survival in dy2J/dy2J mouse of MDC1A.Universality of the network-dynamics of the cell nucleus at high frequencies.Extrasynaptic location of laminin beta 2 chain in developing and adult human skeletal muscle.Substitution of a conserved cysteine-996 in a cysteine-rich motif of the laminin alpha2-chain in congenital muscular dystrophy with partial deficiency of the protein.Mesoangioblast delivery of miniagrin ameliorates murine model of merosin-deficient congenital muscular dystrophy type 1A.Partial laminin alpha2 chain restoration in alpha2 chain-deficient dy/dy mouse by primary muscle cell culture transplantationMerosin and laminin in myogenesis; specific requirement for merosin in myotube stability and survival.alpha-Dystroglycan is a laminin receptor involved in extracellular matrix assembly on myotubes and muscle cell viability.Animal models for muscular dystrophy show different patterns of sarcolemmal disruption.Membrane targeting and stabilization of sarcospan is mediated by the sarcoglycan subcomplex.Conditional disruption of beta 1 integrin in Schwann cells impedes interactions with axons.Laminin gamma1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerveLaminin polymerization induces a receptor-cytoskeleton networkSchwann cell myelination requires integration of laminin activities.Role of integrins in peripheral nerves and hereditary neuropathies.Animal models of muscular dystrophyMerosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models
P2860
Q22001192-4F739674-2B4E-4B7B-89FF-CF5D696E62C7Q22254277-8D98CEE1-05DB-4BC2-9661-668E4070BA1CQ24539119-5A60BA22-25A8-4C04-8FD0-9FBD501AC34CQ24608109-B2B6E30F-1C19-45B4-85BB-1C078D431EC6Q24630157-A6A5C617-E1CB-4713-8743-6D31C71A8D9CQ27318580-F0740F7D-1395-4C66-B2B1-8F657B54C1BCQ27323309-33598976-EAB5-4382-B875-AEFA4D9CC3D5Q27332340-BA723774-E695-438D-B16D-6711B499E925Q28238357-2898E5C9-0D2F-4722-8DF7-F7575C96F71FQ28238601-C7106B26-6EFD-40AC-B96B-2A5E9EE5FBB3Q28249995-EB578AE7-7B03-4E38-A911-AEE6EF6F7056Q28587702-DB5D1D9F-3F96-46A6-829F-BC67D8382A82Q28587952-059E078B-CF89-41D9-AEC6-596A92553495Q28593330-5E488369-F68B-46BD-81CA-D263670C99F8Q30841381-0B3B0484-DC95-46AE-9198-353BA5747146Q34071971-F044E8C3-DAE5-4BC3-85C3-6AEFA3C7094FQ34071975-117F220E-E20F-4EE3-BCA2-113DA136AF85Q34576367-9DB89C40-FC2E-4AB7-920C-DE5BEFAE9698Q34691597-C00C278C-E96C-41B3-BD35-04B34E8A677AQ34806340-00077C75-3383-4412-B1C6-ADB4C5F6B114Q34861423-42E39B2F-1F42-4655-ABB9-2DD1EBE644A5Q35083601-57E9D119-D541-48F1-8FC8-7C4312C02927Q35171165-B5276A73-89EE-41F5-ACE4-B77D8288FA3CQ35274694-A5AEA21A-6480-48E8-B443-A26F8DF9675EQ35291503-2C28F4D2-5F0A-4208-B693-0051E387103BQ35763916-AD435DF0-09F8-4C38-98EC-A9127F906CE0Q35882763-BCA868A9-671E-4115-A08D-5D05F66A2B48Q36027867-41363168-303A-438E-8405-9372402E31B2Q36236670-A9FE7EC2-A387-4FD8-A4D0-144CA50AAE1CQ36237447-E3FFA829-C546-41D5-9BD4-5D94FAEA6660Q36256527-50FF5A98-A201-4DDC-A1D9-AAFE19C6009DQ36273863-0B49F5FE-878D-4146-85E5-05B74E15186EQ36288396-D0E5CA74-864B-4706-9649-6615183998C5Q36324660-7AC3DEC7-06B7-46FE-9677-CB4A0B44A528Q36324885-E3E88F6C-C6C6-4427-A7AF-431B483CD3F9Q36342173-59378E20-AB0E-4B63-A234-48C899B439E5Q36407316-F40A3BE7-1050-4D39-B83F-F4505C33A081Q36507175-777A76F1-7AE3-4654-AF46-77F221D3F65BQ36915922-CB8ED2DB-4913-46A4-A987-E6BCFC2D6E41Q37384623-76796FE1-E1EB-4B42-A43B-AFAC6468689B
P2860
Identification of a novel mutant transcript of laminin alpha 2 chain gene responsible for muscular dystrophy and dysmyelination in dy2J mice.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Identification of a novel muta ...... d dysmyelination in dy2J mice.
@en
Identification of a novel muta ...... d dysmyelination in dy2J mice.
@nl
type
label
Identification of a novel muta ...... d dysmyelination in dy2J mice.
@en
Identification of a novel muta ...... d dysmyelination in dy2J mice.
@nl
prefLabel
Identification of a novel muta ...... d dysmyelination in dy2J mice.
@en
Identification of a novel muta ...... d dysmyelination in dy2J mice.
@nl
P2093
P356
P1476
Identification of a novel muta ...... d dysmyelination in dy2J mice.
@en
P2093
P304
P356
10.1093/HMG/4.6.1055
P577
1995-06-01T00:00:00Z