Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action.
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Oscillations, intercellular coupling, and insulin secretion in pancreatic beta cells.Genetic prediction of future type 2 diabetesTranscriptional regulation of lipid metabolism by fatty acids: a key determinant of pancreatic beta-cell functionSirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cellsReactive oxygen species in health and diseaseRedox homeostasis in pancreatic β cellsOverexpression of GPR40 in pancreatic beta-cells augments glucose-stimulated insulin secretion and improves glucose tolerance in normal and diabetic mice.Foxa2 (HNF3beta ) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin releaseThe basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3Resistance of adipose tissue lipoprotein lipase to insulin action in rats fed an obesity-promoting dietDynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cellsGlucocorticoids modulate amino acid-induced translation initiation in human skeletal muscle.The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study.Individualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data.Genomic structure and expression of uncoupling protein 2 genes in rainbow trout (Oncorhynchus mykiss)Regulation of the uncoupling protein-2 gene in INS-1 beta-cells by oleic acid.UCP-2 and UCP-3 proteins are differentially regulated in pancreatic beta-cells.Mutations in UCP2 in congenital hyperinsulinism reveal a role for regulation of insulin secretionPersistent oxidative stress due to absence of uncoupling protein 2 associated with impaired pancreatic beta-cell function.Diabetic beta-cells can achieve self-protection against oxidative stress through an adaptive up-regulation of their antioxidant defenses.Radioactive Iodine Therapy and Glucose Tolerance.Glucolipotoxicity of the pancreatic beta cell.The RNA binding protein hnRNP-K mediates post-transcriptional regulation of uncoupling protein-2 by angiopoietin-1Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespanUncoupling protein 2 regulates daily rhythms of insulin secretion capacity in MIN6 cells and isolated islets from male miceThe regulation and turnover of mitochondrial uncoupling proteins.Glucose sensing in the pancreatic beta cell: a computational systems analysis.Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass.Loss of AMP-activated protein kinase alpha2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia.Uncoupling protein 2 gene polymorphisms are associated with obesity.Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism.Genetic Variance in Uncoupling Protein 2 in Relation to Obesity, Type 2 Diabetes, and Related Metabolic Traits: Focus on the Functional -866G>A Promoter Variant (rs659366)Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretionUncoupling protein-2 mRNA expression in mice subjected to intermittent hypoxia.Hyperinsulinism and diabetes: genetic dissection of beta cell metabolism-excitation coupling in miceLoss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in β-cells.A biophysical study on molecular physiology of the uncoupling proteins of the central nervous system.Mitochondrial hormesis in pancreatic β cells: does uncoupling protein 2 play a role?Exhaustive training increases uncoupling protein 2 expression and decreases Bcl-2/Bax ratio in rat skeletal muscle.Exposure to bisphenol A induces dysfunction of insulin secretion and apoptosis through the damage of mitochondria in rat insulinoma (INS-1) cells
P2860
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P2860
Increased uncoupling protein-2 levels in beta-cells are associated with impaired glucose-stimulated insulin secretion: mechanism of action.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Increased uncoupling protein-2 ...... ecretion: mechanism of action.
@en
Increased uncoupling protein-2 ...... ecretion: mechanism of action.
@nl
type
label
Increased uncoupling protein-2 ...... ecretion: mechanism of action.
@en
Increased uncoupling protein-2 ...... ecretion: mechanism of action.
@nl
prefLabel
Increased uncoupling protein-2 ...... ecretion: mechanism of action.
@en
Increased uncoupling protein-2 ...... ecretion: mechanism of action.
@nl
P2093
P921
P1433
P1476
Increased uncoupling protein-2 ...... ecretion: mechanism of action.
@en
P2093
A M Salapatek
J W Joseph
M B Wheeler
P S Pennefather
R G Tsushima
T S McQuaid
P304
P356
10.2337/DIABETES.50.6.1302
P407
P577
2001-06-01T00:00:00Z