Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells.
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Phospholipase C delta-4 overexpression upregulates ErbB1/2 expression, Erk signaling pathway, and proliferation in MCF-7 cellsProyl isomerase Pin1 facilitates ubiquitin-mediated degradation of cyclin-dependent kinase 10 to induce tamoxifen resistance in breast cancer cellsNF-kappaB activation in inflammatory breast cancer is associated with oestrogen receptor downregulation, secondary to EGFR and/or ErbB2 overexpression and MAPK hyperactivationHow does the estrogen receptor work?Extreme growth factor signalling can promote oestrogen receptor-alpha loss: therapeutic implications in breast cancerPhytochemicals modulate carcinogenic signaling pathways in breast and hormone-related cancersThe p53-estrogen receptor loop in cancerResistance to therapy in estrogen receptor positive and human epidermal growth factor 2 positive breast cancers: progress with latest therapeutic strategiesMicroRNA cluster 221-222 and estrogen receptor alpha interactions in breast cancerEpidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferationPalmitoylation regulates 17β-estradiol-induced estrogen receptor-α degradation and transcriptional activityActivation of the signal transducer and activator of transcription 3 pathway up-regulates estrogen receptor-beta expression in lung adenocarcinoma cellsPrevalence of the variant allele rs61764370 T>G in the 3'UTR of KRAS among Dutch BRCA1, BRCA2 and non-BRCA1/BRCA2 breast cancer families.Expression of Long-chain Fatty Acyl-CoA Synthetase 4 in Breast and Prostate Cancers Is Associated with Sex Steroid Hormone Receptor Negativity.EGFRvIII-induced estrogen-independence, tamoxifen-resistance phenotype correlates with PgR expression and modulation of apoptotic molecules in breast cancer.GP88 (PC-Cell Derived Growth Factor, progranulin) stimulates proliferation and confers letrozole resistance to aromatase overexpressing breast cancer cellsThe prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer.The role of HER2 in cancer therapy and targeted drug deliveryMolecular and cellular determinants of estrogen receptor alpha expression.Melatonin Attenuates Her-2, p38 MAPK, p-AKT, and mTOR Levels in Ovarian Carcinoma of Ethanol-Preferring RatsOxidized LDL triggers pro-oncogenic signaling in human breast mammary epithelial cells partly via stimulation of MiR-21Estrogen receptor-alpha gene expression in the cortex: sex differences during development and in adulthood.Reverting estrogen-receptor-negative phenotype in HER-2-overexpressing advanced breast cancer patients exposed to trastuzumab plus chemotherapyIdentification and functional annotation of genome-wide ER-regulated genes in breast cancer based on ChIP-Seq data.Inhibition of breast cancer cell invasion by melatonin is mediated through regulation of the p38 mitogen-activated protein kinase signaling pathway.Epigenetic Reactivation of Estrogen Receptor: Promising Tools for Restoring Response to Endocrine Therapy.MEK5/ERK5 signaling suppresses estrogen receptor expression and promotes hormone-independent tumorigenesisThe role of miR-206 in the epidermal growth factor (EGF) induced repression of estrogen receptor-alpha (ERalpha) signaling and a luminal phenotype in MCF-7 breast cancer cells.Mechanisms of Gefitinib-mediated reversal of tamoxifen resistance in MCF-7 breast cancer cells by inducing ERα re-expression.Adaptive changes result in activation of alternate signaling pathways and acquisition of resistance to aromatase inhibitorsCalcitriol restores antiestrogen responsiveness in estrogen receptor negative breast cancer cells: a potential new therapeutic approachMacrophage-elicited loss of estrogen receptor-α in breast cancer cells via involvement of MAPK and c-Jun at the ESR1 genomic locus.Twist contributes to hormone resistance in breast cancer by downregulating estrogen receptor-α.Genome-wide functional screen identifies a compendium of genes affecting sensitivity to tamoxifen.Src promotes estrogen-dependent estrogen receptor alpha proteolysis in human breast cancerp38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription.Estrogen regulates JNK1 genomic localization to control gene expression and cell growth in breast cancer cellsUpregulation of ER Signaling as an Adaptive Mechanism of Cell Survival in HER2-Positive Breast Tumors Treated with Anti-HER2 Therapy.Inhibition of Advanced Glycation End Products (AGEs) Accumulation by Pyridoxamine Modulates Glomerular and Mesangial Cell Estrogen Receptor α Expression in Aged Female Mice.Does lapatinib work against HER2-negative breast cancers?
P2860
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P2860
Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells.
@en
Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells.
@nl
type
label
Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells.
@en
Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells.
@nl
prefLabel
Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells.
@en
Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells.
@nl
P2093
P356
P1476
Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells.
@en
P2093
P304
P356
10.1210/ME.15.8.1344
P577
2001-08-01T00:00:00Z