Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI.
about
Human eosinophils express the high affinity IgE receptor, FcεRI, in bullous pemphigoidFluorogen-activating proteins provide tunable labeling densities for tracking FcεRI independent of IgE.Genome-wide gene expression profiling of human mast cells stimulated by IgE or FcepsilonRI-aggregation reveals a complex network of genes involved in inflammatory responses.The high affinity IgE receptor Fc epsilonRI is expressed by human intestinal epithelial cellsMast cell survival and activation by IgE in the absence of antigen: a consideration of the biologic mechanisms and relevance.Correlation between eosinophils and protection against reinfection with Schistosoma mansoni and the effect of human immunodeficiency virus type 1 coinfection in humans.Omalizumab increases the intrinsic sensitivity of human basophils to IgE-mediated stimulation.IgE by itself affects mature rat mast cell preformed and de novo-synthesized mediator release and amplifies mast cell migratory response.Beyond immediate hypersensitivity: evolving roles for IgE antibodies in immune homeostasis and allergic diseases.CD2 identifies a monocyte subpopulation with immunoglobulin E-dependent, high-level expression of Fc epsilon RIImmunoglobulin E-bearing antigen-presenting cells in atopic dermatitis.The immunoglobulin E receptor: expression and regulation.The role of immunoglobulin E and immune inflammation: implications in allergic rhinitis.IgE and Fc{epsilon}RI regulation.Fcepsilon- and Fcgamma-receptor signaling in diseases.Evidence that IgE molecules mediate a spectrum of effects on mast cell survival and activation via aggregation of the FcepsilonRI.Regulation of the mast cell response to the type 1 Fc epsilon receptor.Pivotal advance: IgE accelerates in vitro development of mast cells and modifies their phenotype.Rabaptin-5 regulates receptor expression and functional activation in mast cells.Enhanced release of IgE-dependent early phase mediators from nasal polyp tissueSerum IgE clearance is facilitated by human FcεRI internalization.Mechanisms of IgE Inflammation.Deciphering the structure and function of FcεRI/mast cell axis in the regulation of allergy and anaphylaxis: a functional genomics paradigm.IgE and mast cells in allergic disease.IgE-dependent signaling as a therapeutic target for allergies.The role of FcεRI expressed in dendritic cells and monocytes.Pharmacokinetics, Pharmacodynamics, and Safety of MEDI4212, an Anti-IgE Monoclonal Antibody, in Subjects with Atopy: A Phase I Study.From IgE to Omalizumab.New insights into basophil heterogeneity.Mechanisms of action that contribute to efficacy of omalizumab in chronic spontaneous urticaria.Systematic characterization of basophil anergy.Evidence for a differential expression of the FcepsilonRIgamma chain in dendritic cells of atopic and nonatopic donors.Roles of the transmembrane domain and the cytoplasmic domain of Fc epsilon RI alpha in immunoglobulin E-mediated up-regulation of surface Fc epsilon RI expression.Transport of the IgE receptor alpha-chain is controlled by a multicomponent intracellular retention signal.A comparative study of the FcepsilonRI molecule on human mast cell and basophil cell lines.Monomeric immunoglobulin E stabilizes FcepsilonRIalpha from the human basophil cell line KU812 by protecting it from natural turnover.The Influence of IgE on Cultured Human Mast Cells.Functional expression of high-affinity receptor for immunoglobulin E on mast cells precedes that of tryptase during differentiation from human bone marrow-derived CD34 progenitors cultured in the presence of stem cell factor and interleukin-6.An intermediate pH unfolding transition abrogates the ability of IgE to interact with its high affinity receptor FcepsilonRIalpha.Are basophil histamine release and high affinity IgE receptor expression involved in asymptomatic skin sensitization?
P2860
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P2860
Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI.
@en
Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI.
@nl
type
label
Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI.
@en
Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI.
@nl
prefLabel
Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI.
@en
Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI.
@nl
P2093
P1476
Minimal requirements for IgE-mediated regulation of surface Fc epsilon RI.
@en
P2093
P304
P356
10.4049/JIMMUNOL.167.3.1290
P407
P577
2001-08-01T00:00:00Z