Nocodazole inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes via a microtubule-independent mechanism.
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Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesinSites of glucose transporter-4 vesicle fusion with the plasma membrane correlate spatially with microtubulesEvidence for a functional interaction between the ClC-2 chloride channel and the retrograde motor dynein complexRequirement of vimentin filament assembly for beta3-adrenergic receptor activation of ERK MAP kinase and lipolysis.Improved glucose homeostasis and enhanced insulin signalling in Grb14-deficient mice.Mannose efflux from the cells: a potential source of mannose in blood.Conventional kinesin KIF5B mediates insulin-stimulated GLUT4 movements on microtubulesGLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomesThe Axin/TNKS complex interacts with KIF3A and is required for insulin-stimulated GLUT4 translocationDynamic GLUT4 sorting through a syntaxin-6 compartment in muscle cells is derailed by insulin resistance-causing ceramide.Akt inhibitors reduce glucose uptake independently of their effects on Akt.Evidence for high-capacity bidirectional glucose transport across the endoplasmic reticulum membrane by genetically encoded fluorescence resonance energy transfer nanosensors.Localization of low density lipoprotein receptor-related protein 1 to caveolae in 3T3-L1 adipocytes in response to insulin treatment.Disruption of microtubules ablates the specificity of insulin signaling to GLUT4 translocation in 3T3-L1 adipocytes.Microtubule network is required for insulin signaling through activation of Akt/protein kinase B: evidence that insulin stimulates vesicle docking/fusion but not intracellular mobility.A pre-docking role for microtubules in insulin-stimulated glucose transporter 4 translocation.Insulin and oleate promote translocation of inosine-5' monophosphate dehydrogenase to lipid bodies.High glucose and insulin promote O-GlcNAc modification of proteins, including alpha-tubulin.Disruption of microtubules in rat skeletal muscle does not inhibit insulin- or contraction-stimulated glucose transport.Insulin recruits GLUT4 from distinct compartments via distinct traffic pathways with differential microtubule dependence in rat adipocytes.Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface.Nocodazole provokes an apoptosis in isopropyl-N-phenyl carbamate resistant and sensitive Nicotiana lines but in two different ways.Nocodazole is a high-affinity ligand for the cancer-related kinases ABL, c-KIT, BRAF, and MEK.
P2860
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P2860
Nocodazole inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes via a microtubule-independent mechanism.
description
2001 nî lūn-bûn
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
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2001年學術文章
@zh-hant
name
Nocodazole inhibits insulin-st ...... otubule-independent mechanism.
@en
Nocodazole inhibits insulin-st ...... otubule-independent mechanism.
@nl
type
label
Nocodazole inhibits insulin-st ...... otubule-independent mechanism.
@en
Nocodazole inhibits insulin-st ...... otubule-independent mechanism.
@nl
prefLabel
Nocodazole inhibits insulin-st ...... otubule-independent mechanism.
@en
Nocodazole inhibits insulin-st ...... otubule-independent mechanism.
@nl
P2860
P356
P1476
Nocodazole inhibits insulin-st ...... rotubule-independent mechanism
@en
P2093
P2860
P304
43829-43835
P356
10.1074/JBC.M105452200
P407
P577
2001-09-24T00:00:00Z