Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells.
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Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentPlacental Responses to Changes in the Maternal Environment Determine Fetal GrowthThe role of placental nutrient sensing in maternal-fetal resource allocationEffects of maternal obesity on placental function and fetal developmentDifferential levels of amino acid transporters System L and ASCT2, and the mTOR protein in placenta of preeclampsia and IUGR.Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in micemTORC2 in the center of cancer metabolic reprogrammingDifferential regulation of placental amino acid transport by saturated and unsaturated fatty acidsMaternal-fetal nutrient transport in pregnancy pathologies: the role of the placentaLabor inhibits placental mechanistic target of rapamycin complex 1 signaling.Emerging function of mTORC2 as a core regulator in glioblastoma: metabolic reprogramming and drug resistance.Impacts of Maternal Nutrition on Vascularity of Nutrient Transferring Tissues during Gestation and LactationRegulation of Human Trophoblast GLUT3 Glucose Transporter by Mammalian Target of Rapamycin SignalingPPARγ stimulates expression of L-type amino acid and taurine transporters in human placentas: the evidence of PPARγ regulating fetal growth.Dietary leucine supplementation minimises tumour-induced damage in placental tissues of pregnant, tumour-bearing ratsS6K1 controls pancreatic β cell size independently of intrauterine growth restrictionAdiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth.Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR.Gene targeting in primary human trophoblasts.Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight.TNF-α stimulates System A amino acid transport in primary human trophoblast cells mediated by p38 MAPK signalingActivation of placental insulin and mTOR signaling in a mouse model of maternal obesity associated with fetal overgrowth.Role of placental nutrient sensing in developmental programmingMechanistic target of rapamycin (mTOR) regulates trophoblast folate uptake by modulating the cell surface expression of FR-α and the RFC.Interleukin-1β inhibits insulin signaling and prevents insulin-stimulated system A amino acid transport in primary human trophoblasts.Placenta plays a critical role in maternal-fetal resource allocation.Positive Regulation of Decidualization by l-Type Amino Acid Transporter 1 (lat1) in Pregnant MiceDown-regulation of placental mTOR, insulin/IGF-I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon.Adiponectin inhibits insulin function in primary trophoblasts by PPARα-mediated ceramide synthesis.Exposure of pregnant mice to triclosan impairs placental development and nutrient transportInsulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells.The SLC38 family of sodium-amino acid co-transporters.The Pasteur's Dictum: Nitrogen Promotes Growth and Oxygen Reduces the Need for Sugar.Regulation of amino acid metabolic enzymes and transporters in plants.Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2.Mechanistic Target of Rapamycin Is a Novel Molecular Mechanism Linking Folate Availability and Cell Function.Role of the Kynurenine Metabolism Pathway in Inflammation-Induced Depression: Preclinical Approaches.A leucine-rich diet modulates the tumor-induced down-regulation of the MAPK/ERK and PI3K/Akt/mTOR signaling pathways and maintains the expression of the ubiquitin-proteasome pathway in the placental tissue of NMRI mice.Metformin, the aspirin of the 21st century: its role in gestational diabetes mellitus, prevention of preeclampsia and cancer, and the promotion of longevity.Essential Roles of L-Type Amino Acid Transporter 1 in Syncytiotrophoblast Development by Presenting Fusogenic 4F2hc.
P2860
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P2860
Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Mammalian target of rapamycin ...... imary human trophoblast cells.
@en
Mammalian target of rapamycin ...... imary human trophoblast cells.
@nl
type
label
Mammalian target of rapamycin ...... imary human trophoblast cells.
@en
Mammalian target of rapamycin ...... imary human trophoblast cells.
@nl
prefLabel
Mammalian target of rapamycin ...... imary human trophoblast cells.
@en
Mammalian target of rapamycin ...... imary human trophoblast cells.
@nl
P2093
P2860
P1476
Mammalian target of rapamycin ...... imary human trophoblast cells.
@en
P2093
Fredrick J Rosario
Thomas Jansson
Yoshikatsu Kanai
P2860
P304
P356
10.1113/JPHYSIOL.2012.238014
P407
P577
2012-11-19T00:00:00Z