Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice.
about
A homozygous mutation in the integrin alpha6 gene in junctional epidermolysis bullosa with pyloric atresiaDigenic junctional epidermolysis bullosa: mutations in COL17A1 and LAMB3 genes.Multiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesisDevelopmental and pathogenic mechanisms of basement membrane assemblyThe slingshot family of phosphatases mediates Rac1 regulation of cofilin phosphorylation, laminin-332 organization, and motility behavior of keratinocytes.Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in miceThe tetraspan molecule CD151, a novel constituent of hemidesmosomes, associates with the integrin alpha6beta4 and may regulate the spatial organization of hemidesmosomesThe beta4 integrin interactor p27(BBP/eIF6) is an essential nuclear matrix protein involved in 60S ribosomal subunit assemblyBinding of integrin alpha6beta4 to plectin prevents plectin association with F-actin but does not interfere with intermediate filament bindingLaminin 5 binds the NC-1 domain of type VII collagenEpidermolysis bullosa with pyloric atresia: novel mutations in the beta4 integrin gene (ITGB4)Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180The localization of bullous pemphigoid antigen 180 (BP180) in hemidesmosomes is mediated by its cytoplasmic domain and seems to be regulated by the beta4 integrin subunitImpact of laminitis on the canonical Wnt signaling pathway in basal epithelial cells of the equine digital laminaeIsolation of a novel beta4 integrin-binding protein (p27(BBP)) highly expressed in epithelial cellsIntegrins as receptors for lamininsGenomic organization of the human integrin beta4 geneIntegrins (alpha7beta1) in muscle function and survival. Disrupted expression in merosin-deficient congenital muscular dystrophyTargeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitectureIntegrin-mediated regulation of epidermal wound functionsProgressive kidney degeneration in mice lacking tensinCharacterization of mice lacking the tetraspanin superfamily member CD151Asymmetric cell divisions promote stratification and differentiation of mammalian skin.Enrichment for murine keratinocyte stem cells based on cell surface phenotypeCre-loxP-mediated inactivation of the alpha6A integrin splice variant in vivo: evidence for a specific functional role of alpha6A in lymphocyte migration but not in heart development.Beta1 integrin-mediated adhesion signalling is essential for epidermal progenitor cell expansion.Anchoring stem cells in the niche by cell adhesion moleculesCaspase proteolysis of the integrin beta4 subunit disrupts hemidesmosome assembly, promotes apoptosis, and inhibits cell migration.Integrins as Therapeutic Targets for Respiratory DiseasesDefining the role of laminin-332 in carcinoma.Adhesion receptors in health and disease.Perturbation of beta1-integrin function alters the development of murine mammary gland.Collagen XVII and BPAG1 expression in the retina: evidence for an anchoring complex in the central nervous system.Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factorThe Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion.Wound healing is defective in mice lacking tetraspanin CD151Novel ITGB4 mutations in lethal and nonlethal variants of epidermolysis bullosa with pyloric atresia: missense versus nonsense.Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor functionAdhesive mechanisms regulating invasion and metastasis in oral cancer.Bridging structure with function: structural, regulatory, and developmental role of laminins.
P2860
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P2860
Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice.
@en
Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice.
@nl
type
label
Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice.
@en
Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice.
@nl
prefLabel
Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice.
@en
Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice.
@nl
P2093
P356
P1433
P1476
Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice.
@en
P2093
Krimpenfort P
Niessen CM
Sonnenberg A
van der Neut R
P2888
P304
P356
10.1038/NG0796-366
P407
P577
1996-07-01T00:00:00Z
P6179
1029490400