Deficiency of the integrin beta 4 subunit in junctional epidermolysis bullosa with pyloric atresia: consequences for hemidesmosome formation and adhesion properties.
about
The protease inhibitor alpha-2-macroglobulin-like-1 is the p170 antigen recognized by paraneoplastic pemphigus autoantibodies in humanA homozygous mutation in the integrin alpha6 gene in junctional epidermolysis bullosa with pyloric atresiaMultiple functions of the integrin alpha6beta4 in epidermal homeostasis and tumorigenesisIdentification of the alpha6 integrin as a candidate receptor for papillomavirusesEpidermolysis bullosa with pyloric atresia: novel mutations in the beta4 integrin gene (ITGB4)Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180The localization of bullous pemphigoid antigen 180 (BP180) in hemidesmosomes is mediated by its cytoplasmic domain and seems to be regulated by the beta4 integrin subunitIdentification of a novel structural variant of the alpha 6 integrinDynamics of the alpha6beta4 integrin in keratinocytes.Unique expression pattern of the alpha6beta4 integrin and laminin-5 in human prostate carcinomaN-glycosylation of ß4 integrin controls the adhesion and motility of keratinocytes.Novel ITGB4 mutations in lethal and nonlethal variants of epidermolysis bullosa with pyloric atresia: missense versus nonsense.Different phenotypes in human prostate cancer: alpha6 or alpha3 integrin in cell-extracellular adhesion sitesKeratinocytes from patients lacking collagen XVII display a migratory phenotypebeta4 integrin and epidermal growth factor coordinately regulate electric field-mediated directional migration via Rac1.Integrin α6β4 identifies an adult distal lung epithelial population with regenerative potential in miceIntegrin clipping: a novel adhesion switch?Compound heterozygosity for missense (L156P) and nonsense (R554X) mutations in the beta4 integrin gene (ITGB4) underlies mild, nonlethal phenotype of epidermolysis bullosa with pyloric atresia.Epidermolysis bullosa simplex associated with pyloric atresia is a novel clinical subtype caused by mutations in the plectin gene (PLEC1)alpha3beta1 Integrin is required for normal development of the epidermal basement membrane.Novel roles for alpha3beta1 integrin as a regulator of cytoskeletal assembly and as a trans-dominant inhibitor of integrin receptor function in mouse keratinocytesLaminin polymerization induces a receptor-cytoskeleton networkβ1 integrin is a crucial regulator of pancreatic β-cell expansion.The human papillomavirus type 8 E2 protein suppresses beta4-integrin expression in primary human keratinocytes.Protein kinase C-alpha phosphorylation of specific serines in the connecting segment of the beta 4 integrin regulates the dynamics of type II hemidesmosomes.Molecular architecture and function of the hemidesmosome.Molecular architecture and function of the hemidesmosome.Integrin alpha 6 beta 4 forms a complex with the cytoskeletal protein HD1 and induces its redistribution in transfected COS-7 cells.Heparanase Inhibitors Facilitate the Assembly of the Basement Membrane in Artificial SkinBasement membrane deposition of nidogen 1 but not nidogen 2 requires the nidogen binding module of the laminin gamma1 chain.The role of laminins in basement membrane function.Granzyme B is elevated in autoimmune blistering diseases and cleaves key anchoring proteins of the dermal-epidermal junction.
P2860
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P2860
Deficiency of the integrin beta 4 subunit in junctional epidermolysis bullosa with pyloric atresia: consequences for hemidesmosome formation and adhesion properties.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Deficiency of the integrin bet ...... ation and adhesion properties.
@en
Deficiency of the integrin bet ...... ation and adhesion properties.
@nl
type
label
Deficiency of the integrin bet ...... ation and adhesion properties.
@en
Deficiency of the integrin bet ...... ation and adhesion properties.
@nl
prefLabel
Deficiency of the integrin bet ...... ation and adhesion properties.
@en
Deficiency of the integrin bet ...... ation and adhesion properties.
@nl
P2093
P1476
Deficiency of the integrin bet ...... mation and adhesion properties
@en
P2093
Hulsman EH
Jonkman MF
Niessen CM
Sonnenberg A
van der Neut R
van der Raaij-Helmer MH
P304
P407
P478
109 ( Pt 7)
P577
1996-07-01T00:00:00Z