Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system.
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Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neuronsOrphan nuclear receptors in drug discoveryMultiple signaling pathways regulate the transcriptional activity of the orphan nuclear receptor NURR1Nurr1 dependent regulation of pro-inflammatory mediators in immortalised synovial fibroblasts.Nuclear receptors in bone physiology and diseasesUnexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expressionThe aetiology of idiopathic Parkinson's diseasePersistent alterations in mesolimbic gene expression with abstinence from cocaine self-administrationChronic methamphetamine administration causes differential regulation of transcription factors in the rat midbrainRequirements for heterodimerization between the orphan nuclear receptor Nurr1 and retinoid X receptorsNurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neuronsInvolvement of Nurr1 in specifying the neurotransmitter identity of ventral midbrain dopaminergic neuronsAge-associated changes in mRNA levels of Phox2, norepinephrine transporter and dopamine beta-hydroxylase in the locus coeruleus and adrenal glands of ratsp57(Kip2) cooperates with Nurr1 in developing dopamine cellsPitx3 activates mouse tyrosine hydroxylase promoter via a high-affinity binding siteEMX1 regulates NRP1-mediated wiring of the mouse anterior cingulate cortex.Nur transcription factors in stress and addictionContexts for dopamine specification by calcium spike activity in the CNSDistribution of the orphan nuclear receptor Nurr1 in medaka (Oryzias latipes): cues to the definition of homologous cell groups in the vertebrate brain.Nurr1 enhances transcription of the human dopamine transporter gene through a novel mechanism.Nur77 and retinoid X receptors: crucial factors in dopamine-related neuroadaptation.Nr4a3, a possibile oncogenic factor for neuroblastoma associated with CpGi methylation within the third exon.Decreased level of Nurr1 in heterozygous young adult mice leads to exacerbated acute and long-term toxicity after repeated methamphetamine exposureNR4A gene expression is dynamically regulated in the ventral tegmental area dopamine neurons and is related to expression of dopamine neurotransmission genes.Silencing mediator of retinoid and thyroid hormone receptors and activating signal cointegrator-2 as transcriptional coregulators of the orphan nuclear receptor Nur77.Mutations in NR4A2 associated with familial Parkinson disease.The constitutive and inducible expression of Nurr1, a key regulator of dopaminergic neuronal differentiation, in human neural and non-neural cell lines.Age-related changes in dopamine signaling in Nurr1 deficient mice as a model of Parkinson's diseaseEnhancing Beta-Catenin Activity via GSK3beta Inhibition Protects PC12 Cells against Rotenone Toxicity through Nurr1 Induction.Nuclear receptors in neurodegenerative diseases.The N-terminal region of Nurr1 (a.a 1-31) is essential for its efficient degradation by the ubiquitin proteasome pathway.Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells.AHR38, a homolog of NGFI-B, inhibits formation of the functional ecdysteroid receptor in the mosquito Aedes aegypti.Differentiation and transcription factor gene therapy in experimental parkinson's disease: sonic hedgehog and Gli-1, but not Nurr-1, protect nigrostriatal cell bodies from 6-OHDA-induced neurodegeneration.Transient transfection of human CDNF gene reduces the 6-hydroxydopamine-induced neuroinflammation in the rat substantia nigraThe role of NR4A transcription factors in memory formationDifferential expression of arc mRNA and other plasticity-related genes induced by nicotine in adolescent rat forebrainRetinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model for Parkinson's disease.Acute stress and nicotine cues interact to unveil locomotor arousal and activity-dependent gene expression in the prefrontal cortexThe atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons.
P2860
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P2860
Cellular expression of the immediate early transcription factors Nurr1 and NGFI-B suggests a gene regulatory role in several brain regions including the nigrostriatal dopamine system.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Cellular expression of the imm ...... nigrostriatal dopamine system.
@en
Cellular expression of the imm ...... nigrostriatal dopamine system.
@nl
type
label
Cellular expression of the imm ...... nigrostriatal dopamine system.
@en
Cellular expression of the imm ...... nigrostriatal dopamine system.
@nl
prefLabel
Cellular expression of the imm ...... nigrostriatal dopamine system.
@en
Cellular expression of the imm ...... nigrostriatal dopamine system.
@nl
P50
P1476
Cellular expression of the imm ...... nigrostriatal dopamine system.
@en
P304
P356
10.1016/0169-328X(96)00074-5
P4011
6d6a034071bc8c2053c69c368b8c61c05ad46380
P577
1996-09-01T00:00:00Z