Kinase/phosphatase overexpression reveals pathways regulating hippocampal neuron morphology.
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Gene-Silencing Screen for Mammalian Axon Regeneration Identifies Inpp5f (Sac2) as an Endogenous Suppressor of Repair after Spinal Cord InjuryProfiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.Prenatal tobacco smoke exposure is associated with childhood DNA CpG methylation.Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.Challenges in small screening laboratories: implementing an on-demand laboratory information management system.Peripheral nervous system genes expressed in central neurons induce growth on inhibitory substrates.Chemical interrogation of the neuronal kinome using a primary cell-based screening assay.A loss-of-function screen for phosphatases that regulate neurite outgrowth identifies PTPN12 as a negative regulator of TrkB tyrosine phosphorylation.Morphology cluster and prediction of growth of human brain pyramidal neuronsERK7 is a negative regulator of protein secretion in response to amino-acid starvation by modulating Sec16 membrane associationThe pseudophosphatase MK-STYX induces neurite-like outgrowths in PC12 cells.Phenotypic assays to identify agents that induce reactive gliosis: a counter-screen to prioritize compounds for preclinical animal studiesPhenotypic Screening of Small-Molecule Inhibitors: Implications for Therapeutic Discovery and Drug Target Development in Traumatic Brain Injury.Rational Polypharmacology: Systematically Identifying and Engaging Multiple Drug Targets To Promote Axon Growth.Role of phosphatidylcholine during neuronal differentiation.Optimization of a 96-Well Electroporation Assay for Postnatal Rat CNS Neurons Suitable for Cost-Effective Medium-Throughput Screening of Genes that Promote Neurite OutgrowthIn vitro models of axon regeneration.Phenotypic screening with primary neurons to identify drug targets for regeneration and degeneration.High content analysis in amyotrophic lateral sclerosis.Dyrk kinases regulate phosphorylation of doublecortin, cytoskeletal organization, and neuronal morphology.The tumor suppressor HHEX inhibits axon growth when prematurely expressed in developing central nervous system neurons.PKACs attenuate innate antiviral response by phosphorylating VISA and priming it for MARCH5-mediated degradation.Hippocampal Transcriptomic Profiles: Subfield Vulnerability to Age and Cognitive Impairment.The mTOR Substrate S6 Kinase 1 (S6K1) Is a Negative Regulator of Axon Regeneration and a Potential Drug Target for Central Nervous System Injury.High Content Screening of Mammalian Primary Cortical Neurons.Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration.Mitochondrial Molecular Abnormalities Revealed by Proteomic Analysis of Hippocampal Organelles of Mice Triple Transgenic for Alzheimer Disease.
P2860
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P2860
Kinase/phosphatase overexpression reveals pathways regulating hippocampal neuron morphology.
description
2010 nî lūn-bûn
@nan
2010年の論文
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2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
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2010年學術文章
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name
Kinase/phosphatase overexpress ...... hippocampal neuron morphology.
@en
Kinase/phosphatase overexpress ...... hippocampal neuron morphology.
@nl
type
label
Kinase/phosphatase overexpress ...... hippocampal neuron morphology.
@en
Kinase/phosphatase overexpress ...... hippocampal neuron morphology.
@nl
prefLabel
Kinase/phosphatase overexpress ...... hippocampal neuron morphology.
@en
Kinase/phosphatase overexpress ...... hippocampal neuron morphology.
@nl
P2860
P50
P356
P1476
Kinase/phosphatase overexpress ...... hippocampal neuron morphology
@en
P2093
Omar Gutierrez-Arenas
Tatiana I Slepak
P2860
P356
10.1038/MSB.2010.52
P577
2010-07-01T00:00:00Z