Cytoskeletal disrupting agents prevent calmodulin kinase, IQ domain and voltage-dependent facilitation of L-type Ca2+ channels.
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Ca(2+) current facilitation is CaMKII-dependent and has arrhythmogenic consequencesCaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylationDifferential regulated interactions of calcium/calmodulin-dependent protein kinase II with isoforms of voltage-gated calcium channel beta subunitsMolecular basis for the modulation of native T-type Ca2+ channels in vivo by Ca2+/calmodulin-dependent protein kinase II.Modeling the actions of beta-adrenergic signaling on excitation--contraction coupling processesModulation of cardiac Ca(V)1.2 channels by dihydropyridine and phosphatase inhibitor requires Ser-1142 in the domain III pore loop.Targeting of calcium/calmodulin-dependent protein kinase II.CaMKII inhibition targeted to the sarcoplasmic reticulum inhibits frequency-dependent acceleration of relaxation and Ca2+ current facilitation.Competition between α-actinin and Ca²⁺-calmodulin controls surface retention of the L-type Ca²⁺ channel Ca(V)1.2.Phosphorylating Titin's Cardiac N2B Element by ERK2 or CaMKIIδ Lowers the Single Molecule and Cardiac Muscle ForceMultiple downstream proarrhythmic targets for calmodulin kinase II: moving beyond an ion channel-centric focus.Ca2+/calmodulin-dependent protein kinase II-dependent remodeling of Ca2+ current in pressure overload heart failure.Retinoschisin, a new binding partner for L-type voltage-gated calcium channels in the retina.The role of calmodulin kinase II in myocardial physiology and disease.Cardiac calmodulin kinase: a potential target for drug design.A novel calmodulin site in the Cav1.2 N-terminus regulates calcium-dependent inactivation.Calmodulin kinase II is involved in voltage-dependent facilitation of the L-type Cav1.2 calcium channel: Identification of the phosphorylation sites.Alterations of L-type calcium current and cardiac function in CaMKII{delta} knockout mice.Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension.Transient receptor potential vanilloid type 1 activation down-regulates voltage-gated calcium channels through calcium-dependent calcineurin in sensory neurons.N-acetylcysteine prevents electrical remodeling and attenuates cellular hypertrophy in epicardial myocytes of rats with ascending aortic stenosis.C terminus L-type Ca2+ channel calmodulin-binding domains are 'auto-agonist' ligands in rabbit ventricular myocytes
P2860
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P2860
Cytoskeletal disrupting agents prevent calmodulin kinase, IQ domain and voltage-dependent facilitation of L-type Ca2+ channels.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Cytoskeletal disrupting agents ...... ation of L-type Ca2+ channels.
@en
Cytoskeletal disrupting agents ...... ation of L-type Ca2+ channels.
@nl
type
label
Cytoskeletal disrupting agents ...... ation of L-type Ca2+ channels.
@en
Cytoskeletal disrupting agents ...... ation of L-type Ca2+ channels.
@nl
prefLabel
Cytoskeletal disrupting agents ...... ation of L-type Ca2+ channels.
@en
Cytoskeletal disrupting agents ...... ation of L-type Ca2+ channels.
@nl
P2093
P2860
P1476
Cytoskeletal disrupting agents ...... ation of L-type Ca2+ channels.
@en
P2093
Igor Dzhura
Jackie D Corbin
Jeffrey R Balser
Mark E Anderson
P2860
P304
P356
10.1113/JPHYSIOL.2002.021881
P407
P577
2002-12-01T00:00:00Z