Characterization of hepatic-specific regulatory elements in the promoter region of the human cholesterol 7alpha-hydroxylase gene.
about
CPF: an orphan nuclear receptor that regulates liver-specific expression of the human cholesterol 7alpha-hydroxylase geneExpression and localization of P1 promoter-driven hepatocyte nuclear factor-4alpha (HNF4alpha) isoforms in human and ratsThe inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimerIdentification and characterization of a 315-base pair enhancer, located more than 55 kilobases 5' of the apolipoprotein B gene, that confers expression in the intestineThe murine and human cholesterol 7alpha-hydroxylase gene promoters are differentially responsive to regulation by fatty acids mediated via peroxisome proliferator-activated receptor alphaElevated levels of hepatocyte nuclear factor 3beta in mouse hepatocytes influence expression of genes involved in bile acid and glucose homeostasis.The CYP7A1 gene rs3808607 variant is associated with susceptibility of tuberculosis in Moroccan population.Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4alpha.A predictive model for regulatory sequences directing liver-specific transcription.Ethnic differences in the prevalence of polymorphisms in CYP7A1, CYP7B1 AND CYP27A1 enzymes involved in cholesterol metabolism.Transient gene delivery for functional enrichment of differentiating embryonic stem cells.Cholesterol-lowing effect of taurine in HepG2 cell.The effect of peroxisome-proliferator-activated receptor-alpha on the activity of the cholesterol 7 alpha-hydroxylase gene.Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays.Peroxisome proliferator-activated receptor-gamma coactivator-1alpha activation of CYP7A1 during food restriction and diabetes is still inhibited by small heterodimer partner.Insulin-dependent suppression of cholesterol 7α-hydroxylase is a possible link between glucose and cholesterol metabolisms.Variants in the promoter region of CYP7A1 are associated with neuromyelitis optica but not with multiple sclerosis in the Han Chinese population.The nuclear matrix protein CDP represses hepatic transcription of the human cholesterol-7alpha hydroxylase gene.Lipoprotein cholesterol uptake mediates up-regulation of bile-acid synthesis by increasing cholesterol 7alpha-hydroxylase but not sterol 27-hydroxylase gene expression in cultured rat hepatocytes.FGF15/FGFR4 integrates growth factor signaling with hepatic bile acid metabolism and insulin action.Identification and characterization of cis-acting elements conferring insulin responsiveness on hamster cholesterol 7alpha-hydroxylase gene promoter.Mice expressing the human CYP7A1 gene in the mouse CYP7A1 knock-out background lack induction of CYP7A1 expression by cholesterol feeding and have increased hypercholesterolemia when fed a high fat diet.Interactions between CYP7A1 A-204C and ABCG8 C1199A polymorphisms on lipid lowering with atorvastatin.
P2860
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P2860
Characterization of hepatic-specific regulatory elements in the promoter region of the human cholesterol 7alpha-hydroxylase gene.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Characterization of hepatic-sp ...... terol 7alpha-hydroxylase gene.
@en
Characterization of hepatic-sp ...... terol 7alpha-hydroxylase gene.
@nl
type
label
Characterization of hepatic-sp ...... terol 7alpha-hydroxylase gene.
@en
Characterization of hepatic-sp ...... terol 7alpha-hydroxylase gene.
@nl
prefLabel
Characterization of hepatic-sp ...... terol 7alpha-hydroxylase gene.
@en
Characterization of hepatic-sp ...... terol 7alpha-hydroxylase gene.
@nl
P2093
P2860
P356
P1476
Characterization of hepatic-sp ...... terol 7alpha-hydroxylase gene.
@en
P2093
A D Cooper
B Levy-Wilson
M J Botelho-Yetkinler
T Taniguchi
P2860
P304
P356
10.1074/JBC.272.6.3444
P407
P577
1997-02-01T00:00:00Z