The effect of deleterious alleles on adaptation in asexual populations.
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Natural selection fails to optimize mutation rates for long-term adaptation on rugged fitness landscapesQuasispecies theory in the context of population geneticsMutational fitness effects in RNA and single-stranded DNA viruses: common patterns revealed by site-directed mutagenesis studiesBeneficial mutation selection balance and the effect of linkage on positive selectionMechanisms of genetic robustness in RNA virusesGenomewide patterns of substitution in adaptively evolving populations of the RNA bacteriophage MS2Deleterious Passengers in Adapting PopulationsThe Evolution of Mutation Rate in Finite Asexual PopulationsThe properties of adaptive walks in evolving populations of fungusFrom bad to good: Fitness reversals and the ascent of deleterious mutationsRecombination speeds adaptation by reducing competition between beneficial mutations in populations of Escherichia coli.Genome-wide analyses reveal lineage specific contributions of positive selection and recombination to the evolution of Listeria monocytogenes.Optimization of amino acid replacement costs by mutational pressure in bacterial genomesMutation and the evolution of recombination.The cost of replication fidelity in an RNA virus.Evolution of sex chromosomes in insects.Evidence for hitchhiking of deleterious mutations within the human genome.The influence of deleterious mutations on adaptation in asexual populations.The speed of evolution and maintenance of variation in asexual populationsTug-of-war between driver and passenger mutations in cancer and other adaptive processesCombining mathematical models and statistical methods to understand and predict the dynamics of antibiotic-sensitive mutants in a population of resistant bacteria during experimental evolution.Probability of fixation of an advantageous mutant in a viral quasispecies.The speed of adaptation in large asexual populations.Evolutionary invasion and escape in the presence of deleterious mutations.The fate of transposable elements in asexual populations.The effects of deleterious mutations on evolution at linked sitesOptimization of Mutation Pressure in Relation to Properties of Protein-Coding Sequences in Bacterial GenomesAdaptive value of high mutation rates of RNA viruses: separating causes from consequences.Lytic phages obscure the cost of antibiotic resistance in Escherichia coli.The temporal dynamics of processes underlying Y chromosome degeneration.Limits to Adaptation in Partially Selfing SpeciesClonal interference, multiple mutations and adaptation in large asexual populations.Evolution of the Insertion-Deletion Mutation Rate Across the Tree of Life.The fixation probability of beneficial mutations.The dynamics of adaptation on correlated fitness landscapesThe relation between recombination rate and patterns of molecular evolution and variation in Drosophila melanogaster.The balance between mutators and nonmutators in asexual populations.Genetic load makes cancer cells more sensitive to common drugs: evidence from Cancer Cell Line Encyclopedia.Delayed lysis confers resistance to the nucleoside analogue 5-fluorouracil and alleviates mutation accumulation in the single-stranded DNA bacteriophage ϕX174.RNA Recombination Enhances Adaptability and Is Required for Virus Spread and Virulence
P2860
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P2860
The effect of deleterious alleles on adaptation in asexual populations.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
The effect of deleterious alleles on adaptation in asexual populations.
@en
The effect of deleterious alleles on adaptation in asexual populations.
@nl
type
label
The effect of deleterious alleles on adaptation in asexual populations.
@en
The effect of deleterious alleles on adaptation in asexual populations.
@nl
prefLabel
The effect of deleterious alleles on adaptation in asexual populations.
@en
The effect of deleterious alleles on adaptation in asexual populations.
@nl
P2860
P1433
P1476
The effect of deleterious alleles on adaptation in asexual populations
@en
P2093
Nick H Barton
Toby Johnson
P2860
P304
P407
P577
2002-09-01T00:00:00Z