Defective platelet activation in G alpha(q)-deficient mice.
about
Protein kinase cascades in the regulation of cardiac hypertrophyAn EF hand mutation in Stim1 causes premature platelet activation and bleeding in miceThe emergence of proteinase-activated receptor-2 as a novel target for the treatment of inflammation-related CNS disordersStructure, Function, Pharmacology, and Therapeutic Potential of the G Protein, Gα/q,11Platelet signalingUnmet needs in the management of acute myocardial infarction: role of novel protease-activated receptor-1 antagonist vorapaxarPKC and AKT Modulate cGMP/PKG Signaling Pathway on Platelet Aggregation in Experimental SepsisPlatelet Shape Changes and Cytoskeleton Dynamics as Novel Therapeutic Targets for Anti-Thrombotic DrugsMultiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functionsHuman platelets bind and degrade 2-arachidonoylglycerol, which activates these cells through a cannabinoid receptorTherapeutic approaches in arterial thrombosisProtein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activationA PLC gamma 2-independent platelet collagen aggregation requiring functional association of GPVI and integrin alpha2beta1Pharmacodynamic characterization of the interaction between the glycoprotein IIb/IIIa inhibitor YM337 and unfractionated heparin and aspirin in humansImpaired activation of murine platelets lacking G alpha(i2)Role of ETB and B2 receptors in the ex vivo platelet inhibitory properties of endothelin and bradykinin in the mouseRagged spiking of free calcium in ADP-stimulated human platelets: regulation of puff-like calcium signals in vitro and ex vivoActivation of the murine EP3 receptor for PGE2 inhibits cAMP production and promotes platelet aggregationADP and platelets: the end of the beginningImpaired motor coordination and persistent multiple climbing fiber innervation of cerebellar Purkinje cells in mice lacking GalphaqHeterotrimeric G proteins of the Gq/11 family are crucial for the induction of maternal behavior in miceEffects of G-protein mutations on skin colorNormal hematopoiesis and inflammatory responses despite discrete signaling defects in Galpha15 knockout miceRole of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapyMultiple neurological abnormalities in mice deficient in the G protein GoActivation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse plateletsAn important role of the SRC family kinase Lyn in stimulating platelet granule secretionEmbryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice.Interaction of G alpha(12) with G alpha(13) and G alpha(q) signaling pathwaysThe P2Y1 receptor mediates ADP-induced p38 kinase-activating factor generation in human plateletsRhoA downstream of G(q) and G(12/13) pathways regulates protease-activated receptor-mediated dense granule release in platelets.Primary megakaryocytes reveal a role for transcription factor NF-E2 in integrin alpha IIb beta 3 signalingPurification, cloning, expression, and mechanism of action of a novel platelet aggregation inhibitor from the salivary gland of the blood-sucking bug, Rhodnius prolixus.Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation.Platelet shape change is mediated by both calcium-dependent and -independent signaling pathways. Role of p160 Rho-associated coiled-coil-containing protein kinase in platelet shape change.Dynamic regulation of microtubule coils in ADP-induced platelet shape change by p160ROCK (Rho-kinase).More pieces of the platelet activation puzzle slide into placePlatelets protect from septic shock by inhibiting macrophage-dependent inflammation via the cyclooxygenase 1 signalling pathway.Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cellsDifferential signaling by protease-activated receptors: implications for therapeutic targeting.
P2860
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P2860
Defective platelet activation in G alpha(q)-deficient mice.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Defective platelet activation in G alpha
@nl
Defective platelet activation in G alpha(q)-deficient mice.
@en
type
label
Defective platelet activation in G alpha
@nl
Defective platelet activation in G alpha(q)-deficient mice.
@en
prefLabel
Defective platelet activation in G alpha
@nl
Defective platelet activation in G alpha(q)-deficient mice.
@en
P2093
P2860
P356
P1433
P1476
Defective platelet activation in G alpha(q)-deficient mice
@en
P2093
P2860
P2888
P304
P356
10.1038/38284
P407
P577
1997-09-01T00:00:00Z
P6179
1009509249