Analyzing CRISPR genome-editing experiments with CRISPResso.
about
Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice.Cas-analyzer: an online tool for assessing genome editing results using NGS data.A truncating mutation in CEP55 is the likely cause of MARCH, a novel syndrome affecting neuronal mitosis.Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.Variant-aware saturating mutagenesis using multiple Cas9 nucleases identifies regulatory elements at trait-associated loci.Muscle-specific CRISPR/Cas9 dystrophin gene editing ameliorates pathophysiology in a mouse model for Duchenne muscular dystrophy.Nrl knockdown by AAV-delivered CRISPR/Cas9 prevents retinal degeneration in mice.Genome-wide Specificity of Highly Efficient TALENs and CRISPR/Cas9 for T Cell Receptor Modification.CRISPR/Cas9 Editing of the Codling Moth (Lepidoptera: Tortricidae) CpomOR1 Gene Affects Egg Production and Viability.Establishment of expanded and streamlined pipeline of PITCh knock-in - a web-based design tool for MMEJ-mediated gene knock-in, PITCh designer, and the variations of PITCh, PITCh-TG and PITCh-KIKO.Quantitative assessment of timing, efficiency, specificity and genetic mosaicism of CRISPR/Cas9-mediated gene editing of hemoglobin beta gene in rhesus monkey embryos.Analysis of Cardiac Myocyte Maturation Using CASAAV, a Platform for Rapid Dissection of Cardiac Myocyte Gene Function In Vivo.ssAAVs containing cassettes encoding SaCas9 and guides targeting hepatitis B virus inactivate replication of the virus in cultured cells.Technical considerations for the use of CRISPR/Cas9 in hematology research.Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes.Efficient CRISPR/Cas9-Mediated Genome Editing Using a Chimeric Single-Guide RNA Molecule.USH2A Gene Editing Using the CRISPR SystemCRISPR-DAV: CRISPR NGS Data Analysis and Visualization Pipeline.Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer.Targeted mutagenesis in a human-parasitic nematode.Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors.In vivo genome editing improves motor function and extends survival in a mouse model of ALS.Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy.Aberrant Activation of a Gastrointestinal Transcriptional Circuit in Prostate Cancer Mediates Castration Resistance.Acute multi-sgRNA knockdown of KEOPS complex genes reproduces the microcephaly phenotype of the stable knockout zebrafish model.What do polymorphisms tell us about the mechanisms of COPD?Genome and epigenome engineering CRISPR toolkit for in vivo modulation of cis-regulatory interactions and gene expression in the chicken embryo.Control of gene editing by manipulation of DNA repair mechanisms.Mediator Kinase Phosphorylation of STAT1 S727 Promotes Growth of Neoplasms With JAK-STAT Activation.CRISPR-Cas9-Edited Site Sequencing (CRES-Seq): An Efficient and High-Throughput Method for the Selection of CRISPR-Cas9-Edited Clones.A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA Damage Response.Therapeutic Genome Editing With CRISPR/Cas9 in a Humanized Mouse Model Ameliorates α1-antitrypsin Deficiency Phenotype.Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling.Easy quantification of template-directed CRISPR/Cas9 editing.Genetic engineering in primary human B cells with CRISPR-Cas9 ribonucleoproteins.Functional significance of co-occurring mutations in PIK3CA and MAP3K1 in breast cancer.Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells.CRISPRMatch: An Automatic Calculation and Visualization Tool for High-throughput CRISPR Genome-editing Data Analysis.AmpUMI: design and analysis of unique molecular identifiers for deep amplicon sequencing.CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens.
P2860
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P2860
Analyzing CRISPR genome-editing experiments with CRISPResso.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
Analyzing CRISPR genome-editing experiments with CRISPResso.
@en
Analyzing CRISPR genome-editing experiments with CRISPResso.
@nl
type
label
Analyzing CRISPR genome-editing experiments with CRISPResso.
@en
Analyzing CRISPR genome-editing experiments with CRISPResso.
@nl
prefLabel
Analyzing CRISPR genome-editing experiments with CRISPResso.
@en
Analyzing CRISPR genome-editing experiments with CRISPResso.
@nl
P2093
P2860
P50
P356
P1433
P1476
Analyzing CRISPR genome-editing experiments with CRISPResso.
@en
P2093
Daniel E Bauer
Donald B Kohn
Stuart H Orkin
P2860
P2888
P304
P356
10.1038/NBT.3583
P577
2016-07-01T00:00:00Z