about
Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. fusion [corrected] inhibitionEfficient trapping of HIV-1 envelope protein by hetero-oligomerization with an N-helix chimera.Inhibition of Henipavirus fusion and infection by heptad-derived peptides of the Nipah virus fusion glycoprotein.Measles Virus Fusion Protein: Structure, Function and InhibitionProtease-resistant peptide design-empowering nature's fragile warriors against HIVNovel approaches to inhibit HIV entryRational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations.Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-A resolutionInhibition of human immunodeficiency virus type 1 infectivity by the gp41 core: role of a conserved hydrophobic cavity in membrane fusionStructural and functional analysis of interhelical interactions in the human immunodeficiency virus type 1 gp41 envelope glycoprotein by alanine-scanning mutagenesis.Design of an engineered N-terminal HIV-1 gp41 trimer with enhanced stability and potencyStructure of the HIV-1 gp41 Membrane-Proximal Ectodomain Region in a Putative Prefusion Conformation † , ‡Role of a Putative gp41 Dimerization Domain in Human Immunodeficiency Virus Type 1 Membrane FusionDesign of a Potent D-Peptide HIV-1 Entry Inhibitor with a Strong Barrier to ResistanceStructural Basis of HIV-1 Neutralization by Affinity Matured Fabs Directed against the Internal Trimeric Coiled-Coil of gp41Broad Antiviral Activity and Crystal Structure of HIV-1 Fusion Inhibitor SifuvirtideDiscovery of Critical Residues for Viral Entry and Inhibition through Structural Insight of HIV-1 Fusion Inhibitor CP621-652Structural Basis of Potent and Broad HIV-1 Fusion Inhibitor CP32MStructure of the Fusion Core and Inhibition of Fusion by a Heptad Repeat Peptide Derived from the S Protein of Middle East Respiratory Syndrome CoronavirusStructure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitorAtomic structure of a thermostable subdomain of HIV-1 gp41Crystal structure of the simian immunodeficiency virus (SIV) gp41 core: conserved helical interactions underlie the broad inhibitory activity of gp41 peptidesHIV entry inhibitors: mechanisms of action and resistance pathwaysDesign of potent inhibitors of HIV-1 entry from the gp41 N-peptide regionEvidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug targetInhibition of HIV type 1 infectivity by constrained alpha-helical peptides: implications for the viral fusion mechanismAsymmetric deactivation of HIV-1 gp41 following fusion inhibitor bindingSusceptibility of HIV-1 subtypes B', CRF07_BC and CRF01_AE that are predominantly circulating in China to HIV-1 entry inhibitorsHIV-1 fusion is blocked through binding of GB Virus C E2-derived peptides to the HIV-1 gp41 disulfide loop [corrected]Molecular dynamics studies of the inhibitor C34 binding to the wild-type and mutant HIV-1 gp41: inhibitory and drug resistant mechanismA molecular clasp in the human immunodeficiency virus (HIV) type 1 TM protein determines the anti-HIV activity of gp41 derivatives: implication for viral fusionEmergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.Visualization of the two-step fusion process of the retrovirus avian sarcoma/leukosis virus by cryo-electron tomography.Viral envelope protein folding and membrane hemifusion are enhanced by the conserved loop region of HIV-1 gp41.Heptad repeat 2-based peptides inhibit avian sarcoma and leukosis virus subgroup a infection and identify a fusion intermediateImproved Pharmacological and Structural Properties of HIV Fusion Inhibitor AP3 over Enfuvirtide: Highlighting Advantages of Artificial Peptide StrategyAntibody elicited against the gp41 N-heptad repeat (NHR) coiled-coil can neutralize HIV-1 with modest potency but non-neutralizing antibodies also bind to NHR mimetics.N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion.Evaluation of "credit card" libraries for inhibition of HIV-1 gp41 fusogenic core formationIdentification of the HIV-1 gp41 core-binding motif--HXXNPF.
P2860
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P2860
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
HIV-1 inhibition by a peptide.
@en
HIV-1 inhibition by a peptide.
@nl
type
label
HIV-1 inhibition by a peptide.
@en
HIV-1 inhibition by a peptide.
@nl
prefLabel
HIV-1 inhibition by a peptide.
@en
HIV-1 inhibition by a peptide.
@nl
P2093
P356
P1433
P1476
HIV-1 inhibition by a peptide.
@en
P2093
P2888
P356
10.1038/365113A0
P407
P577
1993-09-01T00:00:00Z
P6179
1037709060