Endothelin-1 and transforming growth factor-beta1 independently induce fibroblast resistance to apoptosis via AKT activation. - Wikidata - awgldk - TriplyDB

Endothelin-1 and transforming growth factor-beta1 independently induce fibroblast resistance to apoptosis via AKT activation.

Endothelin-1 and transforming growth factor-beta1 independently induce fibroblast resistance to apoptosis via AKT activation.

http://www.wikidata.org/entity/Q42560002

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Therapeutic targeting of redox signaling in myofibroblast differentiation and age-related fibrotic disease Fibroblasts and myofibroblasts in wound healing The fibrosis-cell death axis in heart failure In Situ Cytokine Expression and Morphometric Evaluation of Total Collagen and Collagens Type I and Type III in Keloid Scars.The role of endothelin-1 in the pathogenesis of idiopathic pulmonary fibrosis Lipopolysaccharide induces lung fibroblast proliferation through Toll-like receptor 4 signaling and the phosphoinositide3-kinase-Akt pathway Fibrosis: recent advances in myofibroblast biology and new therapeutic perspectives.Macitentan (ACT-064992), a tissue-targeting endothelin receptor antagonist, enhances therapeutic efficacy of paclitaxel by modulating survival pathways in orthotopic models of metastatic human ovarian cancer.FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1) and Fas.Using bosentan to treat paraquat poisoning-induced acute lung injury in rats.Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis.Antivascular therapy for multidrug-resistant ovarian tumors by macitentan, a dual endothelin receptor antagonist.TGF-β and Smad3 modulate PI3K/Akt signaling pathway in vascular smooth muscle cells Transforming growth factor beta 1 induced endothelin-1 release is peroxisome proliferator-activated receptor gamma dependent in A549 cells Mice, double deficient in lysosomal serine carboxypeptidases Scpep1 and Cathepsin A develop the hyperproliferative vesicular corneal dystrophy and hypertrophic skin thickenings.Serum TGF-β, Serum MMP-1, and HOMA-IR as non-invasive predictors of fibrosis in Egyptian patients with NAFLD Mechanisms of Lung Fibrosis Resolution.Reversal of myofibroblast differentiation by prostaglandin E(2).X-linked inhibitor of apoptosis regulates lung fibroblast resistance to Fas-mediated apoptosis.The pathogenesis of cardiac fibrosis.EZH2 enhances the differentiation of fibroblasts into myofibroblasts in idiopathic pulmonary fibrosis.Hydrogels preserve native phenotypes of valvular fibroblasts through an elasticity-regulated PI3K/AKT pathway.Overexpression of endothelin 1 triggers hepatocarcinogenesis in zebrafish and promotes cell proliferation and migration through the AKT pathway.Transforming growth factor-β1 in plaque morphea.Endothelin in pulmonary fibrosis.Regulation of the pulmonary circulation in the fetus and newborn.Myofibroblast differentiation and survival in fibrotic disease.Hypoxic pulmonary hypertension of the newborn.Redox signaling as a therapeutic target to inhibit myofibroblast activation in degenerative fibrotic disease Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) promotes lung fibroblast proliferation, survival and differentiation to myofibroblasts.Newer developments in idiopathic pulmonary fibrosis in the era of anti-fibrotic medications.Transforming Growth Factor β1 Function in Airway Remodeling and Hyperresponsiveness. The Missing Link?Lung carcinogenesis and fibrosis taken together: just coincidence?Hypermethylation-mediated silencing of p14(ARF) in fibroblasts from idiopathic pulmonary fibrosis.SPARC suppresses apoptosis of idiopathic pulmonary fibrosis fibroblasts through constitutive activation of beta-catenin Endothelin-1 activation of the endothelin B receptor modulates pulmonary endothelial CX3CL1 and contributes to pulmonary angiogenesis in experimental hepatopulmonary syndrome.Antifibrotic effects of curcumin are associated with overexpression of cathepsins K and L in bleomycin treated mice and human fibroblasts.TWIST interacts with endothelin-1/endothelin A receptor signaling in osteosarcoma cell survival against cisplatin.Increased survivin expression contributes to apoptosis-resistance in IPF fibroblasts."Scar-cinoma": viewing the fibrotic lung mesenchymal cell in the context of cancer biology.

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P2860

Endothelin-1 and transforming growth factor-beta1 independently induce fibroblast resistance to apoptosis via AKT activation.

http://www.wikidata.org/entity/Q42560002

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

Endothelin-1 and transforming ...... apoptosis via AKT activation.

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Endothelin-1 and transforming ...... apoptosis via AKT activation.

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type

label

Endothelin-1 and transforming ...... apoptosis via AKT activation.

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Endothelin-1 and transforming ...... apoptosis via AKT activation.

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prefLabel

Endothelin-1 and transforming ...... apoptosis via AKT activation.

@en

Endothelin-1 and transforming ...... apoptosis via AKT activation.

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RCMB.2008-0447OC

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American Journal of Respiratory Cell and Molecular Biology

P1476

Endothelin-1 and transforming ...... apoptosis via AKT activation.

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P2093

Casey A Scavone

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David S Rogers

http://www.w3.org/2001/XMLSchema#string

Douglas A Arenberg

http://www.w3.org/2001/XMLSchema#string

Priya Kulasekaran

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Victor J Thannickal

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P2860

Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway

The myofibroblast: one function, multiple origins

Altered expression of membrane-bound and soluble CD95/Fas contributes to the resistance of fibrotic lung fibroblasts to FasL induced apoptosis

Myofibroblasts and mechano-regulation of connective tissue remodelling

Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy

Cellular survival: a play in three Akts

Fibroblast matrix gene expression and connective tissue remodeling: role of endothelin-1.

Pathophysiology of endothelin in the cardiovascular system.

Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor.

Constitutive activation of prosurvival signaling in alveolar mesenchymal cells isolated from patients with nonresolving acute respiratory distress syndrome.

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484-493

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10.1165/RCMB.2008-0447OC

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4

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41

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Jeffrey C. Horowitz

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23972745

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19188658

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2746991

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