GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon. - Wikidata - awgldk - TriplyDB

GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon.

GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon.

http://www.wikidata.org/entity/Q42561059

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Regulation of immune cell function by short-chain fatty acids Microbial metabolism of dietary components to bioactive metabolites: opportunities for new therapeutic interventions GPR41 and GPR43 in Obesity and Inflammation - Protective or Causative?Butyrate, neuroepigenetics and the gut microbiome: Can a high fiber diet improve brain health?Relationship between intestinal microbiota and colorectal cancer Functional analysis of colonic bacterial metabolism: relevant to health?Cellular and molecular pathways through which commensal bacteria modulate sensitization to dietary antigens The Influence of the Gut Microbiota on Host Physiology: In Pursuit of Mechanisms Gut microbiota-derived short-chain Fatty acids, T cells, and inflammation Type 1 diabetes and gut microbiota: Friend or foe?Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists GPR109A and vascular inflammation Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation Three measurable and modifiable enteric microbial biotransformations relevant to cancer prevention and treatment.Microbiota-derived butyrate suppresses group 3 innate lymphoid cells in terminal ileal Peyer's patches Screening of Different Organs of Rats for HCA2 Receptor mRNA Diet Hypotheses in Light of the Microbiota Revolution: New Perspectives.The impact of the level of the intestinal short chain Fatty acids in inflammatory bowel disease patients versus healthy subjects.Metabolic tinkering by the gut microbiome: Implications for brain development and function Zinc sensing receptor signaling, mediated by GPR39, reduces butyrate-induced cell death in HT29 colonocytes via upregulation of clusterin.Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells.Tributyrin supplementation protects mice from acute ethanol-induced gut injury.The central role of the gut microbiota in chronic inflammatory diseases.Nutrigenetics and nutrigenomics: viewpoints on the current status and applications in nutrition research and practice.A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner.The transition from proliferation to differentiation in colorectal cancer is regulated by the calcium activated chloride channel A1.Lactobacillus GG and tributyrin supplementation reduce antibiotic-induced intestinal injury Nicotinic acid receptor GPR109A is down-regulated in human macrophage-derived foam cells.Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.High dietary niacin may increase prostaglandin formation but does not increase tumor formation in ApcMin/+ mice.The microbiome in infectious disease and inflammation.Butyrate delivered by butyrylated starch increases distal colonic epithelial apoptosis in carcinogen-treated rats.IFNγ Induces DNA Methylation-Silenced GPR109A Expression via pSTAT1/p300 and H3K18 Acetylation in Colon Cancer.Chronically Elevated Levels of Short-Chain Fatty Acids Induce T Cell-Mediated Ureteritis and Hydronephrosis.The microbiome and its potential as a cancer preventive intervention.Biological roles and therapeutic potential of hydroxy-carboxylic Acid receptors.The struggle within: microbial influences on colorectal cancer.Cooperation between the bacterial-derived short-chain fatty acid butyrate and interleukin-22 detected in human Caco2 colon epithelial/carcinoma cells.GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy.

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GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon.

http://www.wikidata.org/entity/Q42561059

description

2009 nî lūn-bûn

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2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

GPR109A is a G-protein-coupled ...... s a tumor suppressor in colon.

@en

GPR109A is a G-protein-coupled ...... s a tumor suppressor in colon.

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type

label

GPR109A is a G-protein-coupled ...... s a tumor suppressor in colon.

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GPR109A is a G-protein-coupled ...... s a tumor suppressor in colon.

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prefLabel

GPR109A is a G-protein-coupled ...... s a tumor suppressor in colon.

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GPR109A is a G-protein-coupled ...... s a tumor suppressor in colon.

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0008-5472.CAN-08-4466

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Cancer Research

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GPR109A is a G-protein-coupled ...... s a tumor suppressor in colon.

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Darren D Browning

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Gail A Cresci

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Gregory J Digby

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Jaya P Gnanaprakasam

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Kebin Liu

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Muthusamy Thangaraju

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Nevin A Lambert

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Puttur D Prasad

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Sudha Ananth

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Sylvia B Smith

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P2860

Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT

SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers

An obesity-associated gut microbiome with increased capacity for energy harvest

Host-bacterial mutualism in the human intestine

Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases

Molecular identification of nicotinic acid receptor

Commensal host-bacterial relationships in the gut

Molecular identification of high and low affinity receptors for nicotinic acid

PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect

Nicotinic acid: pharmacological effects and mechanisms of action

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G protein-coupled receptor

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