Critical ligand binding reagent preparation/selection: when specificity depends on reagents.
about
Advances in BioconjugationConjugated critical reagent characterization for ligand-binding assays: using MALDI-TOF-MS as an orthogonal tool to assess assay performance.Challenges and opportunities in absorption, distribution, metabolism, and excretion studies of therapeutic biologics.Recommendations and best practices for reference standards and reagents used in bioanalytical method validation.Challenges in developing antidrug antibody screening assays.Quality requirements for critical assay reagents used in bioanalysis of therapeutic proteins: what bioanalysts should know about their reagents.Ligand binding assays in the 21st century laboratory: recommendations for characterization and supply of critical reagents.Immunogenicity of therapeutics: a matter of efficacy and safety.Free and total biotherapeutic evaluation in chromatographic assays: interference from targets and immunogenicity.Life cycle management of critical ligand-binding reagents.Current industrial practices and regulatory requirements to assess analyte and reagent stability using ligand-binding assays.Ligand binding assay critical reagents and their stability: recommendations and best practices from the Global Bioanalysis Consortium Harmonization Team.Free analyte QC concept: a novel approach to prove correct quantification of free therapeutic protein drug/biomarker concentrations.Mathematical simulations for bioanalytical assay development: the (un-)necessity and (im-)possibility of free drug quantification.Development of a plug and play ImmunoPCR technique for the analysis of biomolecules.Characterization of labeled reagents in ligand-binding assays by a surface plasmon resonance biosensor.Comparison of an antibody capture and a cell capture ligand-binding assay to quantify a monoclonal therapeutic in serum.Validation and life-cycle management of a quantitative ligand-binding assay for the measurement of Nulojix(®), a CTLA-4-Fc fusion protein, in renal and liver transplant patients.Orthogonal tools to help determine the required selectivity of ligand-binding assays in drug development.Strategic approaches for assessment and minimization of matrix effect in ligand-binding assays.Regulatory considerations for development of bioanalytical assays for biotechnology products.
P2860
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P2860
Critical ligand binding reagent preparation/selection: when specificity depends on reagents.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Critical ligand binding reagen ...... ecificity depends on reagents.
@en
Critical ligand binding reagen ...... ecificity depends on reagents.
@nl
type
label
Critical ligand binding reagen ...... ecificity depends on reagents.
@en
Critical ligand binding reagen ...... ecificity depends on reagents.
@nl
prefLabel
Critical ligand binding reagen ...... ecificity depends on reagents.
@en
Critical ligand binding reagen ...... ecificity depends on reagents.
@nl
P2860
P356
P1433
P1476
Critical ligand binding reagen ...... ecificity depends on reagents.
@en
P2093
Bonita Rup
Denise O'Hara
P2860
P2888
P304
P356
10.1208/AAPSJ0902016
P407
P577
2007-05-11T00:00:00Z
P5875
P6179
1016118823