Aggregated LDL in contact with macrophages induces local increases in free cholesterol levels that regulate local actin polymerization.

Aggregated LDL in contact with macrophages induces local increases in free cholesterol levels that regulate local actin polymerization.

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http://www.wikidata.org/entity/Q42574419
Macrophages create an acidic extracellular hydrolytic compartment to digest aggregated lipoproteins.Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein.Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation.Cholesterol, the central lipid of mammalian cellsMonocyte-Derived Dendritic Cells Upregulate Extracellular Catabolism of Aggregated Low-Density Lipoprotein on Maturation, Leading to Foam Cell FormationDegradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse.Role of endosomes and lysosomes in human disease.Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches.Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells.Angiotensin II impairs endothelial nitric-oxide synthase bioavailability under free cholesterol-enriched conditions via intracellular free cholesterol-rich membrane microdomains.Ceramide activation of RhoA/Rho kinase impairs actin polymerization during aggregated LDL catabolism.Shape Transformations of Lipid Bilayers Following Rapid Cholesterol Uptake.Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths
P2860

Aggregated LDL in contact with macrophages induces local increases in free cholesterol levels that regulate local actin polymerization.

Item
http://www.wikidata.org/entity/Q42574419
description
2009 nî lūn-bûn
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2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Aggregated LDL in contact with ...... te local actin polymerization.
@en
Aggregated LDL in contact with ...... te local actin polymerization.
@nl
type
label
Aggregated LDL in contact with ...... te local actin polymerization.
@en
Aggregated LDL in contact with ...... te local actin polymerization.
@nl
prefLabel
Aggregated LDL in contact with ...... te local actin polymerization.
@en
Aggregated LDL in contact with ...... te local actin polymerization.
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P1433
P1476
P2093
P2860
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Aggregated LDL in contact with ...... ate local actin polymerization
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P2860
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10.1161/ATVBAHA.109.191882
P407
P433
P478
P50
P577
P698
P932