Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14. - Wikidata - awgldk - TriplyDB

Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14.

Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14.

http://www.wikidata.org/entity/Q42589992

about

Recombinant bactericidal/permeability-increasing protein rBPI21 protects against pneumococcal disease The CD14 functional gene polymorphism -260 C>T is not involved in either the susceptibility to Chlamydia trachomatis infection or the development of tubal pathology.SLE-associated risk factors affect DC function Targeting toll-like receptors: promising therapeutic strategies for the management of sepsis-associated pathology and infectious diseases Chitohexaose activates macrophages by alternate pathway through TLR4 and blocks endotoxemia Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa Signal transduction by the lipopolysaccharide receptor, Toll-like receptor-4 Subcellular organelle lipidomics in TLR-4-activated macrophages TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta The tyrosine kinase Syk differentially regulates Toll-like receptor signaling downstream of the adaptor molecules TRAF6 and TRAF3 Toll-like receptor signaling in vertebrates: testing the integration of protein, complex, and pathway data in the protein ontology framework.Distinct roles of pattern recognition receptors CD14 and Toll-like receptor 4 in acute lung injury Glutathione peroxidase-1 modulates lipopolysaccharide-induced adhesion molecule expression in endothelial cells by altering CD14 expression.Human neonatal peripheral blood leukocytes demonstrate pathogen-specific coordinate expression of TLR2, TLR4/MD2, and MyD88 during bacterial infection in vivo.Commensal microflora induce host defense and decrease bacterial translocation in burn mice through toll-like receptor 4.Mycobacterial PIMs inhibit host inflammatory responses through CD14-dependent and CD14-independent mechanisms Identification of specific targets for the gut mucosal defense factor intestinal alkaline phosphatase.Species-specific activation of TLR4 by hypoacylated endotoxins governed by residues 82 and 122 of MD-2 DOK3 negatively regulates LPS responses and endotoxin tolerance.Endotoxin recognition: in fish or not in fish?Human cytomegalovirus induces TLR4 signaling components in monocytes altering TIRAP, TRAM and downstream interferon-beta and TNF-alpha expression.LL-37 protects rats against lethal sepsis caused by gram-negative bacteria Effect of plasma phospholipid transfer protein deficiency on lethal endotoxemia in mice.Inefficient TLR4/MD-2 heterotetramerization by monophosphoryl lipid A Insights into the species-specific TLR4 signaling mechanism in response to Rhodobacter sphaeroides lipid A detection.Glycyrrhizin, the main active compound in liquorice, attenuates pro-inflammatory responses by interfering with membrane-dependent receptor signalling.Biology and pathogenesis of the evolutionarily successful, obligate human bacterium Neisseria meningitidis Activation of toll-like receptor-2 by endogenous matrix metalloproteinase-2 modulates dendritic-cell-mediated inflammatory responses.Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment Deletion of scavenger receptor A gene in mice resulted in protection from septic shock and modulation of TLR4 signaling in isolated peritoneal macrophages.ABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells.Association of neonatal necrotizing enterocolitis with myeloid differentiation-2 and GM2 activator protein genetic polymorphisms.From agonist to antagonist: structure and dynamics of innate immune glycoprotein MD-2 upon recognition of variably acylated bacterial endotoxins Interferon gamma accelerates NF-kappaB activation of biliary epithelial cells induced by Toll-like receptor and ligand interaction.Deficiency in myeloid differentiation factor-2 and toll-like receptor 4 expression attenuates nonalcoholic steatohepatitis and fibrosis in mice.CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance CD36 Differently Regulates Macrophage Responses to Smooth and Rough Lipopolysaccharide.CD14 Is a Co-Receptor for TLR4 in the S100A9-Induced Pro-Inflammatory Response in Monocytes Investigating the Role of TNF-α and IFN-γ Activation on the Dynamics of iNOS Gene Expression in LPS Stimulated Macrophages Expression of toll-like receptor 4 and MD-2 gene and protein in Kupffer cells after ischemia-reperfusion in rat liver graft.

P2860

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P2860

Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14.

http://www.wikidata.org/entity/Q42589992

description

2003 nî lūn-bûn

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2003年の論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年論文

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2003年论文

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2003年论文

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2003年论文

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name

Lipopolysaccharide interaction ...... y than that with MD-2 or CD14.

@en

Lipopolysaccharide interaction ...... y than that with MD-2 or CD14.

@nl

type

label

Lipopolysaccharide interaction ...... y than that with MD-2 or CD14.

@en

Lipopolysaccharide interaction ...... y than that with MD-2 or CD14.

@nl

prefLabel

Lipopolysaccharide interaction ...... y than that with MD-2 or CD14.

@en

Lipopolysaccharide interaction ...... y than that with MD-2 or CD14.

@nl

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P1433

Journal of Experimental Medicine

P1476

Lipopolysaccharide interaction ...... y than that with MD-2 or CD14.

@en

P2093

Atsushi Kosugi

http://www.w3.org/2001/XMLSchema#string

Kensuke Miyake

http://www.w3.org/2001/XMLSchema#string

Koichi Fukase

http://www.w3.org/2001/XMLSchema#string

Noriaki Takamura

http://www.w3.org/2001/XMLSchema#string

Sachiko Akashi

http://www.w3.org/2001/XMLSchema#string

Shin-ichiroh Saitoh

http://www.w3.org/2001/XMLSchema#string

Shoichi Kusumoto

http://www.w3.org/2001/XMLSchema#string

Takane Kikuchi

http://www.w3.org/2001/XMLSchema#string

Yasutaka Wakabayashi

http://www.w3.org/2001/XMLSchema#string

Yoshinori Nagai

http://www.w3.org/2001/XMLSchema#string

P2860

MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2

Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice

Toll-like receptors

Innate immune recognition

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction

CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

P304

1035-1042

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10.1084/JEM.20031076

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7

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198

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2003-09-29T00:00:00Z

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9074275

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14517279

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P921

Toll-like receptor

lipopolysaccharide

P932

2194215

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