Observations in the Synthesis of the Core of the Antitumor Illudins via an Enyne Ring Closing Metathesis Cascade

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Total syntheses of natural products containing spirocarbocycles.Enantioselective total synthesis of (-)-acylfulvene and (-)-irofulven.Synthesis of fused multicyclic compounds containing macrocycles by dienyne ring-closing metathesis and Diels-Alder reactions.

P2860

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P2860

Observations in the Synthesis of the Core of the Antitumor Illudins via an Enyne Ring Closing Metathesis Cascade

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http://www.wikidata.org/entity/Q42590408

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2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

@zh-hk

2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

Observations in the Synthesis ...... ing Closing Metathesis Cascade

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Observations in the Synthesis ...... ing Closing Metathesis Cascade

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type

Item

label

Observations in the Synthesis ...... ing Closing Metathesis Cascade

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Observations in the Synthesis ...... ing Closing Metathesis Cascade

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prefLabel

Observations in the Synthesis ...... ing Closing Metathesis Cascade

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Observations in the Synthesis ...... ing Closing Metathesis Cascade

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P1476

Observations in the Synthesis ...... ing Closing Metathesis Cascade

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P2093

Dustin S Siegel

http://www.w3.org/2001/XMLSchema#string

Grazia Piizzi

http://www.w3.org/2001/XMLSchema#string

Mohammad Movassaghi

http://www.w3.org/2001/XMLSchema#string

P2860

Synthesis and activity of a new generation of ruthenium-based olefin metathesis catalysts coordinated with 1,3-dimesityl-4,5-dihydroimidazol-2-ylidene ligands.

Phase I and pharmacokinetic study of irofulven administered weekly or biweekly in advanced solid tumor patients.

Irofulven as first line therapy in recurrent or metastatic gastric cancer: a phase II multicenter study by the Cancer Therapeutics Research Group (CTRG).

Production of Illudin M and of a Fourth Crystalline Compound by Clitocybe Illudens.

Synthesis and biological activity of enantiomers of antitumor irofulven.

Enantioselective total synthesis of the potent antitumor agent (-)-mucocin using a temporary silicon-tethered ring-closing metathesis cross-coupling reaction.

Ovarian tumor growth regression using a combination of vascular targeting agents anginex or topomimetic 0118 and the chemotherapeutic irofulven

Synergy of irofulven in combination with other DNA damaging agents: synergistic interaction with altretamine, alkylating, and platinum-derived agents in the MV522 lung tumor model.

BRCA1 contributes to cell cycle arrest and chemoresistance in response to the anticancer agent irofulven.

Investigating the role of stereochemistry in the activity of anticancer acylfulvenes: synthesis, reductase-mediated bioactivation, and cellular toxicity.

P304

5489-5492

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P31

scholarly article

P356

10.1016/J.TETLET.2009.07.102

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Giovanni Piersanti

P577

2009-09-01T00:00:00Z

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P5875

41452742

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P698

20160945

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P932

2766079

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Observations in the Synthesis of the Core of the Antitumor Illudins via an Enyne Ring Closing Metathesis Cascade

about

P2860

P2860

Observations in the Synthesis of the Core of the Antitumor Illudins via an Enyne Ring Closing Metathesis Cascade

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P5875

P698

P932