Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine. - Wikidata - awgldk - TriplyDB

Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine.

Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine.

http://www.wikidata.org/entity/Q42590497

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Dopamine release in the basal ganglia The early-onset torsion dystonia-associated protein, torsinA, displays molecular chaperone activity in vitro Genetic background modulates the phenotype of a mouse model of DYT1 dystonia Developmental profile of the aberrant dopamine D2 receptor response in striatal cholinergic interneurons in DYT1 dystonia Striatal cholinergic dysfunction as a unifying theme in the pathophysiology of dystonia Cholinergic dysregulation produced by selective inactivation of the dystonia-associated protein torsinA.In vivo imaging reveals impaired connectivity across cortical and subcortical networks in a mouse model of DYT1 dystonia.Convergent evidence for abnormal striatal synaptic plasticity in dystonia.Evaluation of AZD1446 as a Therapeutic in DYT1 Dystonia.Altered dendritic morphology of Purkinje cells in Dyt1 ΔGAG knock-in and purkinje cell-specific Dyt1 conditional knockout mice.Dysregulation of striatal dopamine release in a mouse model of dystonia.Current Gaps in the Understanding of the Subcellular Distribution of Exogenous and Endogenous Protein TorsinA.Development of allosteric modulators of GPCRs for treatment of CNS disorders Reversal of plasticity-like effects in the human motor cortex The zebrafish homologue of the human DYT1 dystonia gene is widely expressed in CNS neurons but non-essential for early motor system development Short latency cerebellar modulation of the basal ganglia Torsin A Localization in the Mouse Cerebellar Synaptic Circuitry.Cerebellothalamocortical pathway abnormalities in torsinA DYT1 knock-in mice.Pre-synaptic release deficits in a DYT1 dystonia mouse model.Minimal Change in the cytoplasmic calcium dynamics in striatal GABAergic neurons of a DYT1 dystonia knock-in mouse model.Animal models of dystonia: Lessons from a mutant rat.Cholinergic partition cells and lamina x neurons induce a muscarinic-dependent short-term potentiation of commissural glutamatergic inputs in lumbar motoneurons.An anticholinergic reverses motor control and corticostriatal LTD deficits in Dyt1 ΔGAG knock-in mice.Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons.Alternative approaches to modeling hereditary dystonias.Brief mitochondrial inhibition causes lasting changes in motor behavior and corticostriatal synaptic physiology in the Fischer 344 rat.Mouse models of neurodevelopmental disease of the basal ganglia and associated circuits.Radiation dosimetry of [(18)F]VAT in nonhuman primates.Functional analysis of dopaminergic systems in a DYT1 knock-in mouse model of dystonia.Convergent mechanisms in etiologically-diverse dystonias Subtle microstructural changes of the striatum in a DYT1 knock-in mouse model of dystonia.DYT1 dystonia increases risk taking in humans Engineering animal models of dystonia Subtle microstructural changes of the cerebellum in a knock-in mouse model of DYT1 dystonia Dystonia as a network disorder: what is the role of the cerebellum?Neurotransmitter roles in synaptic modulation, plasticity and learning in the dorsal striatum Milestones in dystonia.Striatal cholinergic interneurons in isolated generalized dystonia-rationale and perspectives for stem cell-derived cellular models.Striatal cholinergic interneurons and cortico-striatal synaptic plasticity in health and disease.Probing striatal microcircuitry to understand the functional role of cholinergic interneurons.

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P2860

Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine.

http://www.wikidata.org/entity/Q42590497

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Impairment of bidirectional sy ...... e of endogenous acetylcholine.

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Impairment of bidirectional sy ...... e of endogenous acetylcholine.

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Impairment of bidirectional sy ...... e of endogenous acetylcholine.

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Impairment of bidirectional sy ...... e of endogenous acetylcholine.

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Impairment of bidirectional sy ...... e of endogenous acetylcholine.

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Impairment of bidirectional sy ...... e of endogenous acetylcholine.

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Impairment of bidirectional sy ...... le of endogenous acetylcholine

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Dario Cuomo

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Emanuele Cacci

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Giorgio Bernardi

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Nutan Sharma

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Paola Platania

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Stefano Biagioni

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P2860

The dystonia-associated protein torsinA modulates synaptic vesicle recycling

The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein

A new and rapid colorimetric determination of acetylcholinesterase activity

Antagonist binding profiles of five cloned human muscarinic receptor subtypes

Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1

Immunocytochemical characterization of torsin proteins in mouse brain

Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies

The functional anatomy of basal ganglia disorders

Primate models of movement disorders of basal ganglia origin

Dichotomous dopaminergic control of striatal synaptic plasticity.

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2336-2349

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10.1093/BRAIN/AWP194

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Pt 9

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132

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David G. Standaert

Giuseppina Martella

Alessandro Usiello

Annalisa Tassone

Giuseppe Sciamanna

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2009-07-29T00:00:00Z

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26703892

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19641103

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corpus striatum

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2766181

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