Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice. - Wikidata - awgldk - TriplyDB

Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice.

Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice.

http://www.wikidata.org/entity/Q42592249

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The hypoxia-inducible factor pathway, prolyl hydroxylase domain protein inhibitors, and their roles in bone repair and regeneration Hypoxic regulation of osteoclast differentiation and bone resorption activity Molecular mechanisms of action and therapeutic uses of pharmacological inhibitors of HIF-prolyl 4-hydroxylases for treatment of ischemic diseases Flavonoid Compound Icariin Activates Hypoxia Inducible Factor-1α in Chondrocytes and Promotes Articular Cartilage Repair Angiogenesis in bone regeneration.Localized deferoxamine injection augments vascularity and improves bony union in pathologic fracture healing after radiotherapy.HIF-1α activation results in actin cytoskeleton reorganization and modulation of Rac-1 signaling in endothelial cells A central role for hypoxic signaling in cartilage, bone, and hematopoiesis.Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes Advances in iron chelation: an update.Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4 The prolyl hydroxylase inhibitor dimethyloxalylglycine enhances dentin sialophoshoprotein expression through VEGF-induced Runx2 stabilization Dimethyloxalylglycine prevents bone loss in ovariectomized C57BL/6J mice through enhanced angiogenesis and osteogenesis.Restoring the secretory function of irradiation-damaged salivary gland by administrating deferoxamine in mice.Incorporation of a prolyl hydroxylase inhibitor into scaffolds: a strategy for stimulating vascularization Stimulating angiogenesis mitigates the unloading-induced reduction in osteogenesis in early-stage bone repair in rats.Oxygen-sensing PHDs regulate bone homeostasis through the modulation of osteoprotegerin.Contaminated open fracture and crush injury: a murine model.Deferoxamine enhances bone regeneration in mandibular distraction osteogenesis.MiRNA inhibition in tissue engineering and regenerative medicine.Deferoxamine reverses radiation induced hypovascularity during bone regeneration and repair in the murine mandible.Deferoxamine enhances the vascular response of bone regeneration in mandibular distraction osteogenesis.Quantitative analysis of vascular response after mandibular fracture repair using microcomputed tomography with vessel perfusion.Vascular development during distraction osteogenesis proceeds by sequential intramuscular arteriogenesis followed by intraosteal angiogenesis.Arterial calcification and bone physiology: role of the bone-vascular axis.Translational treatment paradigm for managing non-unions secondary to radiation injury utilizing adipose derived stem cells and angiogenic therapy.Bone regeneration in distraction osteogenesis demonstrates significantly increased vascularity in comparison to fracture repair in the mandible Differential fracture healing resulting from fixation stiffness variability: a mouse model Prevention of radiation-induced bone pathology through combined pharmacologic cytoprotection and angiogenic stimulation.Targeting angiogenesis as a therapeutic means to reinforce osteocyte survival and prevent nonunions in the aftermath of radiotherapy.The role of oxygen during fracture healing Deferoxamine restores callus size, mineralization, and mechanical strength in fracture healing after radiotherapy.Prolyl hydroxylation regulates protein degradation, synthesis, and splicing in human induced pluripotent stem cell-derived cardiomyocytes.The effect of deferoxamine on angiogenesis and bone repair in steroid-induced osteonecrosis of rabbit femoral heads.Tunable delivery of siRNA from a biodegradable scaffold to promote angiogenesis in vivo.Evaluating effects of deferoxamine in a rat tibia critical bone defect model Hypoxia-driven pathways in bone development, regeneration and disease.Hypoxia signalling manipulation for bone regeneration.Prolyl hydroxylase inhibitors act as agents to enhance the efficiency of cell therapy.Glucocorticoids promote Von Hippel Lindau degradation and Hif-1α stabilization.

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P2860

Prolyl hydroxylase inhibitors increase neoangiogenesis and callus formation following femur fracture in mice.

http://www.wikidata.org/entity/Q42592249

description

2009 nî lūn-bûn

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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2009年论文

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2009年论文

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name

Prolyl hydroxylase inhibitors ...... lowing femur fracture in mice.

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Prolyl hydroxylase inhibitors ...... lowing femur fracture in mice.

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type

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Prolyl hydroxylase inhibitors ...... lowing femur fracture in mice.

@en

Prolyl hydroxylase inhibitors ...... lowing femur fracture in mice.

@nl

prefLabel

Prolyl hydroxylase inhibitors ...... lowing femur fracture in mice.

@en

Prolyl hydroxylase inhibitors ...... lowing femur fracture in mice.

@nl

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Journal of Orthopaedic Research

P1476

Prolyl hydroxylase inhibitors ...... lowing femur fracture in mice.

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P2093

Alan Eberhart

http://www.w3.org/2001/XMLSchema#string

Chao Wan

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Craig L Duvall

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Girish Ramaswamy

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Lian Fu Deng

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Mahendra Mavalli

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Robert E Guldberg

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Shawn R Gilbert

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Thomas L Clemens

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Xing Shen

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P2860

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

Hypoxia-inducible factor-1 mediates activation of cultured vascular endothelial cells by inducing multiple angiogenic factors

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

Enhanced bone regeneration associated with decreased apoptosis in mice with partial HIF-1alpha deficiency

Activation of the hypoxia-inducible factor pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

Cloning and characterization of the human tartrate-resistant acid phosphatase (TRAP) gene.

Desferrioxamine, an iron chelator, upregulates cyclooxygenase-2 expression and prostaglandin production in a human macrophage cell line.

Nonsteroidal anti-inflammatory drug-induced fracture nonunion: an inhibition of angiogenesis?

Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover.

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1298-1305

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10.1002/JOR.20886

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10

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P478

27

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P577

2009-10-01T00:00:00Z

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19338032

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3767389

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