CHD5 is down-regulated through promoter hypermethylation in gastric cancer.
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CHD5, a brain-specific paralog of Mi2 chromatin remodeling enzymes, regulates expression of neuronal genesChromodomain-helicase-DNA binding protein 5, 7 and pronecrotic mixed lineage kinase domain-like protein serve as potential prognostic biomarkers in patients with resected pancreatic adenocarcinomasRole of CHD5 in human cancers: 10 years laterRecent progress in the study of methylated tumor suppressor genes in gastric cancerCHD5 is required for spermiogenesis and chromatin condensationChd5 requires PHD-mediated histone 3 binding for tumor suppressionZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancerMicroRNA-211 expression promotes colorectal cancer cell growth in vitro and in vivo by targeting tumor suppressor CHD5Multivalent recognition of histone tails by the PHD fingers of CHD5S-adenosylmethionine inhibits the growth of cancer cells by reversing the hypomethylation status of c-myc and H-ras in human gastric cancer and colon cancer.Copy number and targeted mutational analysis reveals novel somatic events in metastatic prostate tumorsArchitects of the genome: CHD dysfunction in cancer, developmental disorders and neurological syndromesTherapeutic targets for neuroblastomas.Klotho is silenced through promoter hypermethylation in gastric cancer.The tumour suppressor CHD5 forms a NuRD-type chromatin remodelling complex.Mechanisms of CHD5 Inactivation in neuroblastomas.Retinoic acid-induced CHD5 upregulation and neuronal differentiation of neuroblastoma.Homeobox D10 gene, a candidate tumor suppressor, is downregulated through promoter hypermethylation and associated with gastric carcinogenesis.Chromodomain helicase DNA binding protein 5 plays a tumor suppressor role in human breast cancerFunctionally-focused algorithmic analysis of high resolution microarray-CGH genomic landscapes demonstrates comparable genomic copy number aberrations in MSI and MSS sporadic colorectal cancer.Mutual regulation between CHD5 and EZH2 in hepatocellular carcinoma.miR-454 functions as an oncogene by inhibiting CHD5 in hepatocellular carcinomaRole of microRNAs in epigenetic silencing of the CHD5 tumor suppressor gene in neuroblastomas.Annexin A6 is down-regulated through promoter methylation in gastric cancer.Decreased expression of the CHD5 gene and its clinicopathological significance in breast cancer: Correlation with aberrant DNA methylation.Silencing of CHD5 gene by promoter methylation in leukemia.Gastric cancer and related epigenetic alterations.Epigenetic silencing of CHD5, a novel tumor-suppressor gene, occurs in early colorectal cancer stages.The Chromodomain Helicase DNA-Binding Chromatin Remodelers: Family Traits that Protect from and Promote Cancer.Genomic and epigenetic profiles of gastric cancer: potential diagnostic and therapeutic applications.DNA amplification techniques in pharmacogenomics.Drosophila cancer models.miRNA-24-3p promotes cell proliferation and regulates chemosensitivity in head and neck squamous cell carcinoma by targeting CHD5.The tumor suppressor Chd5 is induced during neuronal differentiation in the developing mouse brain.Low CHD5 expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancer.Decreased expression of chromodomain helicase DNA-binding protein 5 is an unfavorable prognostic marker in patients with primary gallbladder carcinoma.Histone deacetylase 3 is associated with gastric cancer cell growth via the miR-454-mediated targeting of CHD5.The single-nucleotide polymorphisms in CHD5 affect the prognosis of patients with hepatocellular carcinoma.CHD5 a tumour suppressor is epigenetically silenced in hepatocellular carcinoma.
P2860
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P2860
CHD5 is down-regulated through promoter hypermethylation in gastric cancer.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
CHD5 is down-regulated through promoter hypermethylation in gastric cancer.
@en
CHD5 is down-regulated through promoter hypermethylation in gastric cancer.
@nl
type
label
CHD5 is down-regulated through promoter hypermethylation in gastric cancer.
@en
CHD5 is down-regulated through promoter hypermethylation in gastric cancer.
@nl
prefLabel
CHD5 is down-regulated through promoter hypermethylation in gastric cancer.
@en
CHD5 is down-regulated through promoter hypermethylation in gastric cancer.
@nl
P2860
P356
P1476
CHD5 is down-regulated through promoter hypermethylation in gastric cancer.
@en
P2093
Kenneth K K Lau
Leo K Y So
P2860
P2888
P356
10.1186/1423-0127-16-95
P577
2009-10-19T00:00:00Z
P5875
P6179
1050580944