Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1. - Wikidata - awgldk - TriplyDB

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.

http://www.wikidata.org/entity/Q42607034

about

Epimutation and cancer: a new carcinogenic mechanism of Lynch syndrome (Review)Era of universal testing of microsatellite instability in colorectal cancer Epigenetics of colorectal cancer A decade of exploring the cancer epigenome - biological and translational implications Microsatellite instability in colorectal cancer Genomic diversity of colorectal cancer: Changing landscape and emerging targets Molecular approach to genetic and epigenetic pathogenesis of early-onset colorectal cancer Cancer predisposition genes: molecular mechanisms and clinical impact on personalized cancer care: examples of Lynch and HBOC syndromes Deficient mismatch repair: Read all about it (Review)Genetic and epigenetic traits as biomarkers in colorectal cancer The fate is not always written in the genes: epigenomics in epidemiologic studies Opportunities for immunotherapy in microsatellite instable colorectal cancer The promise of PD-1 inhibitors in gastro-esophageal cancers: microsatellite instability vs. PD-L1 The genetic heterogeneity of colorectal cancer predisposition - guidelines for gene discovery Role of Deficient Mismatch Repair in the Personalized Management of Colorectal Cancer Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells Hereditary and familial colon cancer EpCAM in carcinogenesis: the good, the bad or the ugly Endometrial cancer gene panels: clinical diagnostic vs research germline DNA testing.Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer.Continuing difficulties in interpreting CNV data: lessons from a genome-wide CNV association study of Australian HNPCC/lynch syndrome patients.Partial loss of heterozygosity events at the mutated gene in tumors from MLH1/MSH2 large genomic rearrangement carriers.A statistical method for single sample analysis of HumanMethylation450 array data: genome-wide methylation analysis of patients with imprinting disorders.Genetic testing strategies in newly diagnosed endometrial cancer patients aimed at reducing morbidity or mortality from lynch syndrome in the index case or her relatives CD3Z hypermethylation is associated with severe clinical manifestations in systemic lupus erythematosus and reduces CD3ζ-chain expression in T cells.Allele-specific CDH1 downregulation and hereditary diffuse gastric cancer.Chemoresistance of colorectal cancer to 5-fluorouracil is associated with silencing of the BNIP3 gene through aberrant methylation Expanding the genetic basis of copy number variation in familial breast cancer.Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles.Somatic hypermethylation of MSH2 is a frequent event in Lynch Syndrome colorectal cancers Patients with colorectal cancer associated with Lynch syndrome and MLH1 promoter hypermethylation have similar prognoses.Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?Hereditary colon cancer: lynch syndrome MSH6 and PMS2 mutation positive Australian Lynch syndrome families: novel mutations, cancer risk and age of diagnosis of colorectal cancer.The Alu-rich genomic architecture of SPAST predisposes to diverse and functionally distinct disease-associated CNV alleles.Gene regulation by the act of long non-coding RNA transcription The mutational spectrum of Lynch syndrome in cyprus.High-level microsatellite instability in appendiceal carcinomas.Application of molecular diagnostics for the detection of Lynch syndrome.Genetics talks to epigenetics? The interplay between sequence variants and chromatin structure

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P2860

Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.

http://www.wikidata.org/entity/Q42607034

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Heritable somatic methylation ...... on of the 3' exons of TACSTD1.

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Heritable somatic methylation ...... on of the 3' exons of TACSTD1.

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type

label

Heritable somatic methylation ...... on of the 3' exons of TACSTD1.

@en

Heritable somatic methylation ...... on of the 3' exons of TACSTD1.

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prefLabel

Heritable somatic methylation ...... on of the 3' exons of TACSTD1.

@en

Heritable somatic methylation ...... on of the 3' exons of TACSTD1.

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Nature Genetics

P1476

Heritable somatic methylation ...... on of the 3' exons of TACSTD1.

@en

P2093

Ad Geurts van Kessel

http://www.w3.org/2001/XMLSchema#string

Chi Kwan Kong

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Danielle Bodmer

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Eveline Hoenselaar

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Han G Brunner

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J Han J M van Krieken

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Konnie M Hebeda

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Marjolijn J L Ligtenberg

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Marsha Voorendt

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Monique Goossens

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P2860

Identification of EpCAM as the gene for congenital tufting enteropathy

Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

Transcription of antisense RNA leading to gene silencing and methylation as a novel cause of human genetic disease.

Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer.

The epithelial cell adhesion molecule (Ep-CAM) as a morphoregulatory molecule is a tool in surgical pathology

New perspectives on connecting messenger RNA 3' end formation to transcription.

Connections between mRNA 3' end processing and transcription termination.

Patients with an unexplained microsatellite instable tumour have a low risk of familial cancer

Isolation and characterization of the human mismatch repair gene hMSH2 promoter region.

P2888

P304

112-117

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10.1038/NG.283

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1

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41

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Adrianus Henricus Maria Geurts van Kessel

Nicoline Hoogerbrugge

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2008-12-21T00:00:00Z

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23680449

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1024370549

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19098912

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