Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism
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Identification of DISE-inducing shRNAs by monitoring cellular responses.Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells.Long noncoding RNA complementarity and target transcripts abundance.DISE: A Seed-Dependent RNAi Off-Target Effect That Kills Cancer Cells.Stage-dependent piRNAs in chicken implicated roles in modulating male germ cell development.OSM potentiates preintravasation events, increases CTC counts, and promotes breast cancer metastasis to the lung.6mer seed toxicity in tumor suppressive microRNAs
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P2860
Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism
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Many si/shRNAs can kill cancer ...... hrough an off-target mechanism
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Many si/shRNAs can kill cancer ...... hrough an off-target mechanism
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Many si/shRNAs can kill cancer ...... hrough an off-target mechanism
@en
Many si/shRNAs can kill cancer ...... hrough an off-target mechanism
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Many si/shRNAs can kill cancer ...... hrough an off-target mechanism
@en
Many si/shRNAs can kill cancer ...... hrough an off-target mechanism
@nl
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Many si/shRNAs can kill cancer ...... hrough an off-target mechanism
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Aishe A Sarshad
Andrea E Murmann
Denise M Scholtens
Jonathan C Zhao
Stijn van Dongen
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10.7554/ELIFE.29702
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2017-10-24T00:00:00Z