Cloning and sequencing of the gene encoding a novel lysine-specific cysteine proteinase (Lys-gingipain) in Porphyromonas gingivalis: structural relationship with the arginine-specific cysteine proteinase (Arg-gingipain).
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A peptide domain on gingipain R which confers immunity against Porphyromonas gingivalis infection in mice.RgpA-Kgp peptide-based immunogens provide protection against Porphyromonas gingivalis challenge in a murine lesion model.A Porphyromonas gingivalis mutant defective in a putative glycosyltransferase exhibits defective biosynthesis of the polysaccharide portions of lipopolysaccharide, decreased gingipain activities, strong autoaggregation, and increased biofilm formatiActivities of the Porphyromonas gingivalis PrtP proteinase determined by construction of prtP-deficient mutants and expression of the gene in Bacteroides species.Role of Arg-gingipain A in virulence of Porphyromonas gingivalisIS195, an insertion sequence-like element associated with protease genes in Porphyromonas gingivalis.Contact-dependent protein secretion in Porphyromonas gingivalisRegulation of protease expression in Porphyromonas gingivalis.Genomic loci of the Porphyromonas gingivalis insertion element IS1126.Binding specificity of the Porphyromonas gingivalis heme and hemoglobin receptor HmuR, gingipain K, and gingipain R1 for heme, porphyrins, and metalloporphyrinsDegradation of host heme proteins by lysine- and arginine-specific cysteine proteinases (gingipains) of Porphyromonas gingivalis.Molecular mechanism for the spontaneous generation of pigmentless Porphyromonas gingivalis mutants.Transposition of the endogenous insertion sequence element IS1126 modulates gingipain expression in Porphyromonas gingivalis.Serum immunoglobulin G (IgG) and IgG subclass responses to the RgpA-Kgp proteinase-adhesin complex of Porphyromonas gingivalis in adult periodontitisvimA gene downstream of recA is involved in virulence modulation in Porphyromonas gingivalis W83.Specific antibodies to Porphyromonas gingivalis Lys-gingipain by DNA vaccination inhibit bacterial binding to hemoglobin and protect mice from infection.Role of RgpA, RgpB, and Kgp proteinases in virulence of Porphyromonas gingivalis W50 in a murine lesion model.Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis.Cysteine proteases of Porphyromonas gingivalis.The RgpB C-terminal domain has a role in attachment of RgpB to the outer membrane and belongs to a novel C-terminal-domain family found in Porphyromonas gingivalisGingipain RgpB is excreted as a proenzyme in the vimA-defective mutant Porphyromonas gingivalis FLL92.The Tla protein of Porphyromonas gingivalis W50: a homolog of the RI protease precursor (PrpRI) is an outer membrane receptor required for growth on low levels of hemin.Activation of the kallikrein-kinin system and release of new kinins through alternative cleavage of kininogens by microbial and human cell proteinases.Iron and heme utilization in Porphyromonas gingivalis.Using Tn-seq To Identify Pigmentation-Related Genes of Porphyromonas gingivalis: Characterization of the Role of a Putative Glycosyltransferase.Involvement of an Skp-Like Protein, PGN_0300, in the Type IX Secretion System of Porphyromonas gingivalis.The gingipains: scissors and glue of the periodontal pathogen, Porphyromonas gingivalis.Host immune responses to Porphyromonas gingivalis antigens.Gingipains from Porphyromonas gingivalis - Complex domain structures confer diverse functionsHeme acquisition mechanisms of Porphyromonas gingivalis - strategies used in a polymicrobial community in a heme-limited host environment.Effect of temperature on growth, hemagglutination, and protease activity of Porphyromonas gingivalis.Characterization of Porphyromonas gingivalis-induced degradation of epithelial cell junctional complexes.Porphyromonas gingivalis gingipains and adhesion to epithelial cells.Localization of HArep-containing genes on the chromosome of Porphyromonas gingivalis W83.A functional virulence complex composed of gingipains, adhesins, and lipopolysaccharide shows high affinity to host cells and matrix proteins and escapes recognition by host immune systems.A combination of both arginine- and lysine-specific gingipain activity of Porphyromonas gingivalis is necessary for the generation of the micro-oxo bishaem-containing pigment from haemoglobin.GingisKHAN™ protease cleavage allows a high-throughput antibody to Fab conversion enabling direct functional assessment during lead identification of human monoclonal and bispecific IgG1 antibodies.A Porphyromonas gingivalis genetic locus encoding a heme transport system.Determination and characterization of the hemagglutinin-associated short motifs found in Porphyromonas gingivalis multiple gene products.Protease-active extracellular protein preparations from Porphyromonas gingivalis W83 induce N-cadherin proteolysis, loss of cell adhesion, and apoptosis in human epithelial cells.
P2860
Q32036004-9200ACEB-D02C-4CD4-8C42-22723020BE6BQ33597234-C3721D2B-5777-4A0D-929A-E314DB9D51DFQ33631022-2DC6716A-37CA-40EC-AB85-2D5BF1EB77E8Q33634983-E20156C1-8609-4FCD-BD36-096CFB340D4DQ33751695-553D4BB2-D0C3-4AC2-93AF-023D46F44360Q33755813-38C88440-4E54-4E6F-9702-94B000D4DD75Q33765304-295D9739-FA96-4DFB-ACAD-7DB96C3A7407Q33767494-12664FE5-A842-404D-BCD5-BB7438282443Q33876777-11624F08-65CA-41D4-9E91-9542A8C07F3DQ33996913-10C1EEBA-A35B-4CD2-A396-8FF8C0DDB5B5Q33996920-E3561EC8-A33C-4E58-BCEE-CF2879C1E46AQ34001911-6F6DC04D-1727-460A-BB11-FB9A4F316A89Q34001976-1780047A-E10F-46C8-9521-E31D6ED0961DQ34004291-6051534E-1070-4B0D-9233-758907394F60Q34005626-AF9DD45A-1DBE-446E-ABC7-4725F297BAD7Q34007214-46D2F762-36D9-4BF7-98FE-401CB54AC7C4Q34009727-F309207E-9A34-4DDE-A102-DCABE025E675Q34010067-791EC427-CBA9-40A3-9E16-1F0C9DF756A2Q34332243-58831117-08E9-491E-89A5-4B463AEC5C3CQ35075282-9C105150-60AC-4D81-BE06-28B1104443ECQ35106177-644E6BBC-5E3E-441E-9345-DF27477E2B17Q35626963-6EF2B44F-1387-4573-A36C-50AA57352329Q35970392-FFAC233D-7F84-465A-8848-CE312859A83DQ36010834-F42329E6-7D7F-4C02-AC86-DF2EA0E6598BQ36366485-781BE0AE-A606-416F-BCEC-2F851C36D2EBQ36410939-F7D5B751-91C2-4873-864F-95C5B22BFC7CQ37470595-D1F33406-A147-498A-AA75-4F91727F9130Q37657669-D5216D47-DDE5-44C2-AE06-612171301CBAQ38182102-29508CE5-FCAC-4F91-986C-DB94811C42A8Q38668096-C9A2EC8F-EE08-46E1-AB0D-67DFCC3EEAB8Q39510560-669FE613-0FAA-475E-B05C-FE4F5AA06860Q39514636-6AE00963-1256-4FC6-B8BE-4FEFFA7F87BEQ39519857-A576C7AB-2344-4B9D-9918-5D143C03759FQ39610718-276BD402-6F52-47F0-BA45-7298E0A881DDQ40997028-D042969E-89F2-4604-8A76-FBDABF725FF0Q42081808-F2917E0A-0409-4482-9010-A2C05C0CA6D5Q42280827-20B693B2-F009-439D-BFEE-E10DE332702FQ42640749-62785FC9-EBFD-405A-8CC2-CF2CF8C83B96Q42692155-AF082687-3F1A-41C2-AE44-A40EE8105DECQ43631259-4E582592-6AD9-4DEA-BBF7-74F2EB2164DA
P2860
Cloning and sequencing of the gene encoding a novel lysine-specific cysteine proteinase (Lys-gingipain) in Porphyromonas gingivalis: structural relationship with the arginine-specific cysteine proteinase (Arg-gingipain).
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Cloning and sequencing of the ...... ne proteinase (Arg-gingipain).
@en
Cloning and sequencing of the gene encoding a novel lysine-specific cysteine proteinase
@nl
type
label
Cloning and sequencing of the ...... ne proteinase (Arg-gingipain).
@en
Cloning and sequencing of the gene encoding a novel lysine-specific cysteine proteinase
@nl
prefLabel
Cloning and sequencing of the ...... ne proteinase (Arg-gingipain).
@en
Cloning and sequencing of the gene encoding a novel lysine-specific cysteine proteinase
@nl
P2093
P1476
Cloning and sequencing of the ...... ne proteinase (Arg-gingipain).
@en
P2093
Kadowaki T
Nakayama K
Yamamoto K
P304
P356
10.1093/OXFORDJOURNALS.JBCHEM.A021426
P577
1996-08-01T00:00:00Z