Functional expression of the menkes disease protein reveals common biochemical mechanisms among the copper-transporting P-type ATPases.
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Binding of copper(I) by the Wilson disease protein and its copper chaperoneCopper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7ABiochemical basis of regulation of human copper-transporting ATPasesMolecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypesInteraction of the copper chaperone HAH1 with the Wilson disease protein is essential for copper homeostasisA mutational study in the transmembrane domain of Ccc2p, the yeast Cu(I)-ATPase, shows different roles for each Cys-Pro-Cys cysteine.Functional characterization of missense mutations in ATP7B: Wilson disease mutation or normal variant?Kinetic analysis of the interaction of the copper chaperone Atox1 with the metal binding sites of the Menkes proteinBiochemical and genetic analyses of yeast and human high affinity copper transporters suggest a conserved mechanism for copper uptakeSupplying copper to the cuproenzyme peptidylglycine alpha-amidating monooxygenaseThe Lys1010-Lys1325 fragment of the Wilson's disease protein binds nucleotides and interacts with the N-terminal domain of this protein in a copper-dependent manner.The Princeton Protein Orthology Database (P-POD): a comparative genomics analysis tool for biologistsFunctional expression of the Wilson disease protein reveals mislocalization and impaired copper-dependent trafficking of the common H1069Q mutation.The role of metal binding and phosphorylation domains in the regulation of cisplatin-induced trafficking of ATP7B.A conditional mutation affecting localization of the Menkes disease copper ATPase. Suppression by copper supplementation.Functional copper transport explains neurologic sparing in occipital horn syndrome.The high copper tolerance of Candida albicans is mediated by a P-type ATPase.Clinical outcomes in Menkes disease patients with a copper-responsive ATP7A mutation, G727R.An overview and update of ATP7A mutations leading to Menkes disease and occipital horn syndrome.Expression, purification and copper-binding studies of the first metal-binding domain of Menkes protein.The role of GMXCXXC metal binding sites in the copper-induced redistribution of the Menkes protein.Localization of the Wilson disease protein in murine intestine.The different intermolecular interactions of the soluble copper-binding domains of the menkes protein, ATP7A.Functional properties of the copper-transporting ATPase ATP7B (the Wilson's disease protein) expressed in insect cells.Characterization of the Menkes protein copper-binding domains and their role in copper-induced protein relocalization.An NMR study of the interaction of the N-terminal cytoplasmic tail of the Wilson disease protein with copper(I)-HAH1.A possible regulatory role for the metal-binding domain of CadA, the Listeria monocytogenes Cd2+-ATPase.ATP-dependent copper transport by the Menkes protein in membrane vesicles isolated from cultured Chinese hamster ovary cells.The regulation of catalytic activity of the menkes copper-translocating P-type ATPase. Role of high affinity copper-binding sites.Copper-regulated trafficking of the Menkes disease copper ATPase is associated with formation of a phosphorylated catalytic intermediate.Complementation of Saccharomyces cerevisiae ccc2 mutant by a putative P1B-ATPase from Brassica napus supports a copper-transporting function.Identification of the transmembrane metal binding site in Cu+-transporting PIB-type ATPases.Heavy metal transport by AtHMA4 involves the N-terminal degenerated metal binding domain and the C-terminal His11 stretch.Twenty-five novel mutations including duplications in the ATP7A gene.Sequence variation in the ATP-binding domain of the Wilson disease transporter, ATP7B, affects copper transport in a yeast model system.Identification of the copper chaperone, CUC-1, in Caenorhabditis elegans: tissue specific co-expression with the copper transporting ATPase, CUA-1.Analysis of functional domains of Wilson disease protein (ATP7B) in Saccharomyces cerevisiae.Deletion of the copper transporter CaCCC2 reveals two distinct pathways for iron acquisition in Candida albicans.Expression of the human Menkes ATPase in Xenopus laevis oocytes.Molecular regulation of copper excretion in the liver
P2860
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P2860
Functional expression of the menkes disease protein reveals common biochemical mechanisms among the copper-transporting P-type ATPases.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Functional expression of the m ...... r-transporting P-type ATPases.
@en
Functional expression of the m ...... r-transporting P-type ATPases.
@nl
type
label
Functional expression of the m ...... r-transporting P-type ATPases.
@en
Functional expression of the m ...... r-transporting P-type ATPases.
@nl
prefLabel
Functional expression of the m ...... r-transporting P-type ATPases.
@en
Functional expression of the m ...... r-transporting P-type ATPases.
@nl
P2860
P356
P1476
Functional expression of the m ...... r-transporting P-type ATPases.
@en
P2093
P2860
P304
P356
10.1074/JBC.273.6.3765
P407
P577
1998-02-01T00:00:00Z