Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-gamma, but not IFN-alpha, signaling. - Wikidata - awgldk - TriplyDB

Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-gamma, but not IFN-alpha, signaling.

Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-gamma, but not IFN-alpha, signaling.

http://www.wikidata.org/entity/Q42673076

about

Genome-wide association scan of dental caries in the permanent dentition.Interferon-gamma-dependent tyrosine phosphorylation of MEKK4 via Pyk2 is regulated by annexin II and SHP2 in keratinocytes Modulation of Activation-Loop Phosphorylation by JAK Inhibitors Is Binding Mode Dependent Specificity of signaling by STAT1 depends on SH2 and C-terminal domains that regulate Ser727 phosphorylation, differentially affecting specific target gene expression.Pyk2 regulates multiple signaling events crucial for macrophage morphology and migration.JAK-STAT signaling mediates gangliosides-induced inflammatory responses in brain microglial cells Autophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation.Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulator.Interleukin (IL)-7 induces rapid activation of Pyk2, which is bound to Janus kinase 1 and IL-7Ralpha.Serine phosphorylation of STATs.Israeli acute paralysis virus: epidemiology, pathogenesis and implications for honey bee health Global cross-talk of genes of the mosquito Aedes aegypti in response to dengue virus infection.JAK2 tyrosine kinase phosphorylates and is negatively regulated by centrosomal protein Ninein.The Jak/STAT pathway is involved in synaptic plasticity Promyelocytic leukemia protein (PML) regulates endothelial cell network formation and migration in response to tumor necrosis factor α (TNFα) and interferon α (IFNα).IFN-γ elicits macrophage autophagy via the p38 MAPK signaling pathway.Negative regulation of FAK signaling by SOCS proteins.Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway.Targeting PYK2 mediates microenvironment-specific cell death in multiple myeloma.Epithelial to mesenchymal transition promotes breast cancer progression via a fibronectin-dependent STAT3 signaling pathway.Induction of TRIM22 by IFN-γ Involves JAK and PC-PLC/PKC, but Not MAPKs and pI3K/Akt/mTOR Pathways.Cross-regulation of signaling by ITAM-associated receptors.Protein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727.Dendritic cells activated by IFN-γ/STAT1 express IL-31 receptor and release proinflammatory mediators upon IL-31 treatment.Glycogen synthase kinase-3β indirectly facilitates interferon-γ-induced nuclear factor-κB activation and nitric oxide biosynthesis.Involvement of ERK and JNK pathways in IFN-γ-induced B7-DC expression on tumor cells.Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways.Requirement of histone deacetylase activity for signaling by STAT1.Pyk2 amplifies epidermal growth factor and c-Src-induced Stat3 activation.Signalling events involved in interferon-gamma-inducible macrophage nitric oxide generation.The TEL-Jak2 oncoprotein induces Socs1 expression and altered cytokine response in Ba/F3 cells.Protein-tyrosine kinase Pyk2 mediates endothelin-induced p38 MAPK activation in glomerular mesangial cells.Role of STAT1 in the breast.Thrombin-stimulated phosphatidylinositol 3-kinase activity in platelets is associated with activation of PYK2 tyrosine kinase: activation of both enzymes is aggregation independent.Regulation of tyrosine phosphorylation of PYK2 in vascular endothelial cells by lysophosphatidylcholine.Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling.MSK1 and JNKs mediate phosphorylation of STAT3 in UVA-irradiated mouse epidermal JB6 cells.A PI-3 kinase-dependent, Stat1-independent signaling pathway regulates interferon-stimulated monocyte adhesion.Influence of IFN-gamma on gene expression in normal human bronchial epithelial cells: modulation of IFN-gamma effects by dexamethasone.

P2860

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P2860

Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-gamma, but not IFN-alpha, signaling.

http://www.wikidata.org/entity/Q42673076

description

1999 nî lūn-bûn

@nan

1999年の論文

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1999年論文

@yue

1999年論文

@zh-hant

1999年論文

@zh-hk

1999年論文

@zh-mo

1999年論文

@zh-tw

1999年论文

@wuu

1999年论文

@zh

1999年论文

@zh-cn

name

Protein tyrosine kinase Pyk2 m ...... but not IFN-alpha, signaling.

@en

Protein tyrosine kinase Pyk2 m ...... but not IFN-alpha, signaling.

@nl

type

label

Protein tyrosine kinase Pyk2 m ...... but not IFN-alpha, signaling.

@en

Protein tyrosine kinase Pyk2 m ...... but not IFN-alpha, signaling.

@nl

prefLabel

Protein tyrosine kinase Pyk2 m ...... but not IFN-alpha, signaling.

@en

Protein tyrosine kinase Pyk2 m ...... but not IFN-alpha, signaling.

@nl

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P1433

The EMBO Journal

P1476

Protein tyrosine kinase Pyk2 m ...... but not IFN-alpha, signaling.

@en

P2093

Decker T

http://www.w3.org/2001/XMLSchema#string

Fujii H

http://www.w3.org/2001/XMLSchema#string

Kovarik P

http://www.w3.org/2001/XMLSchema#string

Mitani Y

http://www.w3.org/2001/XMLSchema#string

Miyazaki T

http://www.w3.org/2001/XMLSchema#string

Sato M

http://www.w3.org/2001/XMLSchema#string

Schlessinger J

http://www.w3.org/2001/XMLSchema#string

Takaoka A

http://www.w3.org/2001/XMLSchema#string

Tanaka N

http://www.w3.org/2001/XMLSchema#string

Taniguchi T

http://www.w3.org/2001/XMLSchema#string

P2860

Functional role of type I and type II interferons in antiviral defense

Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

Structure and regulation of the human interferon regulatory factor 1 (IRF-1) and IRF-2 genes: implications for a gene network in the interferon system

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation

Activation of Pyk2 by stress signals and coupling with JNK signaling pathway

The integrity of the conserved 'WS motif' common to IL-2 and other cytokine receptors is essential for ligand binding and signal transduction

STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation

Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling

P304

2480-2488

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scholarly article

P356

10.1093/EMBOJ/18.9.2480

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P433

9

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P478

18

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1999-05-01T00:00:00Z

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232761357

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10228162

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P932

1171330

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