Deciphering the biosynthesis pathway of the antitumor thiocoraline from a marine actinomycete and its expression in two streptomyces species.
about
Discovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type-I Polyketide Synthases Derived from Marine Microbiomes.Identification of Sare0718 as an alanine-activating adenylation domain in marine actinomycete Salinispora arenicola CNS-205Genetic basis for the biosynthesis of the pharmaceutically important class of epoxyketone proteasome inhibitors.Marine Rare Actinobacteria: Isolation, Characterization, and Strategies for Harnessing Bioactive Compounds.Isolation of marine bacteria with antimicrobial activities from cultured and field-collected soft corals.Thiocoraline activates the Notch pathway in carcinoids and reduces tumor progression in vivoMapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products.Drug targets in mycobacterial sulfur metabolism.Nonribosomal peptide synthetases involved in the production of medically relevant natural products.New targets and inhibitors of mycobacterial sulfur metabolism.First natural analogs of the cytotoxic thiodepsipeptide thiocoraline A from a marine Verrucosispora sp.Molecular networking and pattern-based genome mining improves discovery of biosynthetic gene clusters and their products from Salinispora species.Strain-level diversity of secondary metabolism in Streptomyces albusSeasonal changes in bacterial communities associated with healthy and diseased Porites coral in southern Taiwan.Research on marine actinobacteria in India.Nonribosomal Peptide Synthesis-Principles and Prospects.Genomes to natural products PRediction Informatics for Secondary Metabolomes (PRISM)Explorations of catalytic domains in non-ribosomal peptide synthetase enzymologyIdentification and utility of FdmR1 as a Streptomyces antibiotic regulatory protein activator for fredericamycin production in Streptomyces griseus ATCC 49344 and heterologous hosts.Bioprospecting Red Sea Coastal Ecosystems for Culturable Microorganisms and Their Antimicrobial Potential.Escherichia coli allows efficient modular incorporation of newly isolated quinomycin biosynthetic enzyme into echinomycin biosynthetic pathway for rational design and synthesis of potent antibiotic unnatural natural product.Metabolites from symbiotic bacteria.Antitumor compounds from marine actinomycetes.Insights into naturally minimised Streptomyces albus J1074 genome.Biosynthetic potential-based strain prioritization for natural product discovery: a showcase for diterpenoid-producing actinomycetes.Recent advances in thiopeptide antibiotic biosynthesis.Antibacterials from the sea.Frontiers and opportunities in chemoenzymatic synthesis.Strain improvement in actinomycetes in the postgenomic era.Molecular insights on the biosynthesis of antitumour compounds by actinomycetes.Ribosome-independent biosynthesis of biologically active peptides: Application of synthetic biology to generate structural diversity.Expression of biosynthetic gene clusters in heterologous hosts for natural product production and combinatorial biosynthesis.Biosynthetic modularity rules in the bisintercalator family of antitumor compounds.Interrupted adenylation domains: unique bifunctional enzymes involved in nonribosomal peptide biosynthesis.Non-ribosomal peptide synthetases: Identifying the cryptic gene clusters and decoding the natural product.Systematic and biotechnological aspects of halophilic and halotolerant actinomycetes.Biosynthesis of 8-hydroxyquinoline-2-carboxylic acid, an iron chelator from the gut of the lepidopteran Spodoptera littoralis.An insight into the "-omics" based engineering of streptomycetes for secondary metabolite overproduction.In vivo characterization of nonribosomal peptide synthetases NocA and NocB in the biosynthesis of nocardicin A.Molecular basis for chloronium-mediated meroterpene cyclization: cloning, sequencing, and heterologous expression of the napyradiomycin biosynthetic gene cluster.
P2860
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P2860
Deciphering the biosynthesis pathway of the antitumor thiocoraline from a marine actinomycete and its expression in two streptomyces species.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Deciphering the biosynthesis p ...... n in two streptomyces species.
@en
Deciphering the biosynthesis p ...... n in two streptomyces species.
@nl
type
label
Deciphering the biosynthesis p ...... n in two streptomyces species.
@en
Deciphering the biosynthesis p ...... n in two streptomyces species.
@nl
prefLabel
Deciphering the biosynthesis p ...... n in two streptomyces species.
@en
Deciphering the biosynthesis p ...... n in two streptomyces species.
@nl
P2093
P2860
P50
P356
P1433
P1476
Deciphering the biosynthesis p ...... n in two streptomyces species.
@en
P2093
Ana Velasco
Angelina Castro
Fernando de la Calle
José A Salas
P2860
P304
P356
10.1002/CBIC.200500325
P577
2006-02-01T00:00:00Z