Isolation and characterization of the Candida albicans gene for mRNA 5'-triphosphatase: association of mRNA 5'-triphosphatase and mRNA 5'-guanylyltransferase activities is essential for the function of mRNA 5'-capping enzyme in vivo.
about
RNA triphosphatase is essential in Schizosaccharomyces pombe and Candida albicansA conserved domain of yeast RNA triphosphatase flanking the catalytic core regulates self-association and interaction with the guanylyltransferase component of the mRNA capping apparatus.Characterization of human, Schizosaccharomyces pombe, and Candida albicans mRNA cap methyltransferases and complete replacement of the yeast capping apparatus by mammalian enzymesCharacterization of Candida albicans RNA triphosphatase and mutational analysis of its active site.Energetics of RNA binding by the West Nile virus RNA triphosphatase.Inhibition of a metal-dependent viral RNA triphosphatase by decavanadateDivergent subunit interactions among fungal mRNA 5'-capping machineriesCharacterization of Schizosaccharomyces pombe RNA triphosphatase.The essential interaction between yeast mRNA capping enzyme subunits is not required for triphosphatase function in vivo.Deletion of individual mRNA capping genes is unexpectedly not lethal to Candida albicans and results in modified mRNA cap structures.Magnesium-binding studies reveal fundamental differences between closely related RNA triphosphatases.The length, phosphorylation state, and primary structure of the RNA polymerase II carboxyl-terminal domain dictate interactions with mRNA capping enzymes.Cell-based assays to detect inhibitors of fungal mRNA capping enzymes and characterization of sinefungin as a cap methyltransferase inhibitor.What messenger RNA capping tells us about eukaryotic evolution.
P2860
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P2860
Isolation and characterization of the Candida albicans gene for mRNA 5'-triphosphatase: association of mRNA 5'-triphosphatase and mRNA 5'-guanylyltransferase activities is essential for the function of mRNA 5'-capping enzyme in vivo.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Isolation and characterization ...... RNA 5'-capping enzyme in vivo.
@en
Isolation and characterization ...... RNA 5'-capping enzyme in vivo.
@nl
type
label
Isolation and characterization ...... RNA 5'-capping enzyme in vivo.
@en
Isolation and characterization ...... RNA 5'-capping enzyme in vivo.
@nl
prefLabel
Isolation and characterization ...... RNA 5'-capping enzyme in vivo.
@en
Isolation and characterization ...... RNA 5'-capping enzyme in vivo.
@nl
P2093
P2860
P1433
P1476
Isolation and characterization ...... RNA 5'-capping enzyme in vivo.
@en
P2093
Yamada-Okabe H
Yamada-Okabe T
P2860
P356
10.1016/S0014-5793(98)01037-0
P407
P577
1998-09-01T00:00:00Z