Vaccinia virus serpins B13R (SPI-2) and B22R (SPI-1) encode M(r) 38.5 and 40K, intracellular polypeptides that do not affect virus virulence in a murine intranasal model.
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Myxoma virus Serp2 is a weak inhibitor of granzyme B and interleukin-1beta-converting enzyme in vitro and unlike CrmA cannot block apoptosis in cowpox virus-infected cellsPoxvirus tropismNLRs, inflammasomes, and viral infectionThe inflammasome as a target of modulation by DNA virusesThe role of inflammasome modulation in virulenceInflammasomes: caspase-1-activating platforms with critical roles in host defenseCentral roles of NLRs and inflammasomes in viral infectionInduction of potent humoral and cell-mediated immune responses by attenuated vaccinia virus vectors with deleted serpin genes.Pox proteomics: mass spectrometry analysis and identification of Vaccinia virion proteins.A novel highly reproducible and lethal nonhuman primate model for orthopox virus infectionViral modulation of the host response via crmA/SPI-2 expression.Role of genes that modulate host immune responses in the immunogenicity and pathogenicity of vaccinia virus.Activation of caspases in pig kidney cells infected with wild-type and CrmA/SPI-2 mutants of cowpox and rabbitpox virusesSerp2, an inhibitor of the interleukin-1beta-converting enzyme, is critical in the pathobiology of myxoma virus.Vaccinia virus vectors with an inactivated gamma interferon receptor homolog gene (B8R) are attenuated In vivo without a concomitant reduction in immunogenicityThe vaccinia virus superoxide dismutase-like protein (A45R) is a virion component that is nonessential for virus replication.Caspases in virus-infected cells contribute to recognition by CD8+ T lymphocytes.The TNFR family members OX40 and CD27 link viral virulence to protective T cell vaccines in miceVaccinia virus uracil DNA glycosylase has an essential role in DNA synthesis that is independent of its glycosylase activity: catalytic site mutations reduce virulence but not virus replication in cultured cells.The ectromelia virus SPI-2 protein causes lethal mousepox by preventing NK cell responsesOrthopoxvirus fusion inhibitor glycoprotein SPI-3 (open reading frame K2L) contains motifs characteristic of serine proteinase inhibitors that are not required for control of cell fusion.Characterization of a myxoma virus-encoded serpin-like protein with activity against interleukin-1 beta-converting enzymeProtection against apoptosis by the vaccinia virus SPI-2 (B13R) gene productDouble-stranded RNA is a trigger for apoptosis in vaccinia virus-infected cells.Evasion of innate immunity by vaccinia virus.Targeting 4-1BB (CD137) to enhance CD8 T cell responses with poxviruses and viral antigens.Understanding orthopoxvirus interference with host immune responses to inform novel vaccine design.Effects of vaccinia virus uracil DNA glycosylase catalytic site and deoxyuridine triphosphatase deletion mutations individually and together on replication in active and quiescent cells and pathogenesis in mice.A mechanism for the inhibition of fever by a virus.Vaccinia virus induces programmed necrosis in ovarian cancer cellsThe highly attenuated oncolytic recombinant vaccinia virus GLV-1h68: comparative genomic features and the contribution of F14.5L inactivation.Differential inhibition of the Fas- and granule-mediated cytolysis pathways by the orthopoxvirus cytokine response modifier A/SPI-2 and SPI-1 protein.Triad of human cellular proteins, IRF2, FAM111A, and RFC3, restrict replication of orthopoxvirus SPI-1 host-range mutants.Analysis of the anti-apoptotic activity of four vaccinia virus proteins demonstrates that B13 is the most potent inhibitor in isolation and during viral infectionVaccinia virus infection disarms the mitochondrion-mediated pathway of the apoptotic cascade by modulating the permeability transition poreA rabbitpox virus serpin gene controls host range by inhibiting apoptosis in restrictive cellsSPI-2/CrmA inhibits IFN-β induction by targeting TBK1/IKKε.Poxviruses Utilize Multiple Strategies to Inhibit Apoptosis.A new recombinant vaccinia with targeted deletion of three viral genes: its safety and efficacy as an oncolytic virus.Predicting the subcellular localization of viral proteins within a mammalian host cell.
P2860
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P2860
Vaccinia virus serpins B13R (SPI-2) and B22R (SPI-1) encode M(r) 38.5 and 40K, intracellular polypeptides that do not affect virus virulence in a murine intranasal model.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Vaccinia virus serpins B13R (S ...... in a murine intranasal model.
@en
Vaccinia virus serpins B13R (S ...... in a murine intranasal model.
@nl
type
label
Vaccinia virus serpins B13R (S ...... in a murine intranasal model.
@en
Vaccinia virus serpins B13R (S ...... in a murine intranasal model.
@nl
prefLabel
Vaccinia virus serpins B13R (S ...... in a murine intranasal model.
@en
Vaccinia virus serpins B13R (S ...... in a murine intranasal model.
@nl
P2093
P1433
P1476
Vaccinia virus serpins B13R (S ...... in a murine intranasal model.
@en
P2093
P304
P356
10.1016/S0042-6822(95)80028-X
P407
P577
1995-01-01T00:00:00Z