Computational methods for identifying a layered allosteric regulatory mechanism for ALS-causing mutations of Cu-Zn superoxide dismutase 1

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Fine-tuning multiprotein complexes using small molecules Global structural motions from the strain of a single hydrogen bond Building SuperModels: emerging patient avatars for use in precision and systems medicine SOD1 exhibits allosteric frustration to facilitate metal binding affinity.

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Computational methods for identifying a layered allosteric regulatory mechanism for ALS-causing mutations of Cu-Zn superoxide dismutase 1

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2011 nî lūn-bûn

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2011年の論文

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Computational methods for iden ...... f Cu-Zn superoxide dismutase 1

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Computational methods for iden ...... f Cu-Zn superoxide dismutase 1

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Computational methods for iden ...... f Cu-Zn superoxide dismutase 1

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Computational methods for iden ...... f Cu-Zn superoxide dismutase 1

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Computational methods for iden ...... f Cu-Zn superoxide dismutase 1

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Computational methods for iden ...... f Cu-Zn superoxide dismutase 1

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Computational methods for iden ...... f Cu-Zn superoxide dismutase 1

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Adam D Schuyler

http://www.w3.org/2001/XMLSchema#string

Eva L Feldman

http://www.w3.org/2001/XMLSchema#string

Heather A Carlson

http://www.w3.org/2001/XMLSchema#string

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The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis

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Small molecule inhibitors of the MDM2-p53 interaction discovered by ensemble-based receptor models.

A poke in the eye: inhibiting HIV-1 protease through its flap-recognition pocket

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417-427

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scholarly article

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10.1002/PROT.22892

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English

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Adam D Schuyler

Heather A Carlson

Eva L Feldman

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2011-02-01T00:00:00Z

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49633120

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21104697

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amyotrophic lateral sclerosis

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3058251

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Computational methods for identifying a layered allosteric regulatory mechanism for ALS-causing mutations of Cu-Zn superoxide dismutase 1

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P2860

P2860

Computational methods for identifying a layered allosteric regulatory mechanism for ALS-causing mutations of Cu-Zn superoxide dismutase 1

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P5875

P698

P921

P932