Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation.
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Expression and functional analysis of CYP2D6.24, CYP2D6.26, CYP2D6.27, and CYP2D7 isozymesMolecular genetics of CYP2D6: clinical relevance with focus on psychotropic drugsPharmacogenetics of healthy volunteers in Puerto RicoInfluence of the CYP2D6*10 allele on the metabolism of mexiletine by human liver microsomesPlasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patientsIdentification of new alleles and the determination of alleles and genotypes frequencies at the CYP2D6 gene in EmiratisSystematic functional study of cytochrome P450 2D6 promoter polymorphisms in the Chinese Han populationPolymorphisms of xenobiotic-metabolizing enzymes and susceptibility to cancerTowards the clinical implementation of pharmacogenetics in bipolar disorder.In vitro metabolism of exemestane by hepatic cytochrome P450s: impact of nonsynonymous polymorphisms on formation of the active metabolite 17β-dihydroexemestaneCYP2D6: novel genomic structures and alleles.Oxycodone overdose in the pediatric population: case files of the University of Massachusetts Medical Toxicology FellowshipReduced CYP2D6 function is associated with gefitinib-induced rash in patients with non-small cell lung cancer.Genetic polymorphisms of CYP2D6*10 and the effectiveness of combined tamoxifen citrate and testosterone undecanoate treatment in infertile men with idiopathic oligozoospermiaInfluence of ABCB1 genetic polymorphisms on the pharmacokinetics of risperidone in healthy subjects with CYP2D6*10/*10Novel +90G>A Intronic Polymorphism of CYP2D6.Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assaysPrevalence of the CYP2D6*10 (C100T), *4 (G1846A), and *14 (G1758A) alleles among Iranians of different ethnicities.Disposition of debrisoquine and nortriptyline in Korean subjects in relation to CYP2D6 genotypes, and comparison with CaucasiansEffects of various factors on steady-state plasma concentrations of risperidone and 9-hydroxyrisperidone: lack of impact of MDR-1 genotypesRelationship between Type A and B personality and debrisoquine hydroxylation capacityCYP2D6 polymorphism in a Gabonese population: contribution of the CYP2D6*2 and CYP2D6*17 alleles to the high prevalence of the intermediate metabolic phenotype.Phenotypes and genotypes for CYP2D6 and CYP2C19 in a black Tanzanian population.Three new alternative splicing variants of human cytochrome P450 2D6 mRNA in human extratumoral liver tissueComparison of antiemetic efficacy of granisetron and ondansetron in Oriental patients: a randomized crossover study.The role of pharmacogenetics in cancer therapeutics.Polymorphisms in the CYP1B1 gene are associated with increased risk of prostate cancer.Effects of imatinib (Glivec) on the pharmacokinetics of metoprolol, a CYP2D6 substrate, in Chinese patients with chronic myelogenous leukaemia.Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.Role of cytochrome P450 2D6 genetic polymorphism in carvedilol hydroxylation in vitroFactors affecting the development of adverse drug reactions to β-blockers in hospitalized cardiac patient populationFrequencies of Functional Polymorphisms in Three Pharmacokinetic Genes of Clinical Interest within the Admixed Puerto Rican PopulationQuantitation of human cytochrome P450 2D6 protein with immunoblot and mass spectrometry analysis.A Study on CYP2C19 and CYP2D6 Polymorphic Effects on Pharmacokinetics and Pharmacodynamics of Amitriptyline in Healthy Koreans.Effect of the CYP2D6*10 genotype on venlafaxine pharmacokinetics in healthy adult volunteers.Intronic polymorphisms of cytochromes P450.CYP2D6 P34S Polymorphism and Outcomes of Escitalopram Treatment in Koreans with Major Depression.CYP2D6 genotyping as an alternative to phenotyping for determination of metabolic status in a clinical trial setting.The influence of cytochrome P450 pharmacogenetics on disposition of common antidepressant and antipsychotic medications.Response to serotonin reuptake inhibitors in OCD is not influenced by common CYP2D6 polymorphisms.
P2860
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P2860
Genetic analysis of the Chinese cytochrome P4502D locus: characterization of variant CYP2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Genetic analysis of the Chines ...... or debrisoquine hydroxylation.
@en
Genetic analysis of the Chines ...... or debrisoquine hydroxylation.
@nl
type
label
Genetic analysis of the Chines ...... or debrisoquine hydroxylation.
@en
Genetic analysis of the Chines ...... or debrisoquine hydroxylation.
@nl
prefLabel
Genetic analysis of the Chines ...... or debrisoquine hydroxylation.
@en
Genetic analysis of the Chines ...... or debrisoquine hydroxylation.
@nl
P2093
P1476
Genetic analysis of the Chines ...... for debrisoquine hydroxylation
@en
P2093
Bertilsson L
Ingelman-Sundberg M
Johansson I
Oscarson M
Sjöqvist F
P304
P577
1994-09-01T00:00:00Z