Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis.
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A review of UHMWPE wear-induced osteolysis: the role for early detection of the immune response.Molecular Characterization of Macrophage-Biomaterial InteractionsInnate Immunity and Biomaterials at the Nexus: Friends or FoesParticle disease: biologic mechanisms of periprosthetic osteolysis in total hip arthroplasty.Central roles of NLRs and inflammasomes in viral infectionThe inflammasome NLRs in immunity, inflammation, and associated diseasesIncreasing both CoCrMo-alloy particle size and surface irregularity induces increased macrophage inflammasome activation in vitro potentially through lysosomal destabilization mechanismsThe pathology of orthopedic implant failure is mediated by innate immune system cytokines.TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infectionBacterial pathogen-associated molecular patterns stimulate biological activity of orthopaedic wear particles by activating cognate Toll-like receptorsDo tissues from THA revision of highly crosslinked UHMWPE liners contain wear debris and associated inflammation?Innate immunity sensors participating in pathophysiology of joint diseases: a brief overview.Do genetic susceptibility, Toll-like receptors, and pathogen-associated molecular patterns modulate the effects of wear?Lysine392, a K63-linked ubiquitination site in NEMO, mediates inflammatory osteoclastogenesis and osteolysisRole of polyethylene particles in peri-prosthetic osteolysis: A review.The annexin A2/S100A10 system in health and disease: emerging paradigmsMacrophages-Key cells in the response to wear debris from joint replacements.Allergy or tolerance: reduced inflammatory cytokine response and concomitant IL-10 production of lymphocytes and monocytes in symptom-free titanium dental implant patientsAnnexin A2 system in human biology: cell surface and beyond.The role of the NLRP3 inflammasome in gout.The role of TLR and chemokine in wear particle-induced aseptic loosening.Chronic inflammation in biomaterial-induced periprosthetic osteolysis: NF-κB as a therapeutic target.Toll-like receptors-2 and 4 are overexpressed in an experimental model of particle-induced osteolysis.The biological response to orthopedic implants for joint replacement. II: Polyethylene, ceramics, PMMA, and the foreign body reaction.Myxoma virus lacking the pyrin-like protein M013 is sensed in human myeloid cells by both NLRP3 and multiple Toll-like receptors, which independently activate the inflammasome and NF-κB innate response pathways.Activation of innate immunity by lysozyme fibrils is critically dependent on cross-β sheet structure.Annexin A2 binds to endosomes following organelle destabilization by particulate wear debris.Joint replacement surgery and the innate immune system.Inflammatory osteolysis: a conspiracy against bone.Innate immune response and implant loosening: Interferon gamma is inversely associated with early migration of total knee prostheses.Role of macrophages in the biological reaction to wear debris from joint replacements.Macrophage polarization and activation in response to implant debris: influence by "particle disease" and "ion disease"Polyethylene wear particles induce TLR 2 upregulation in the synovial layer of mice.Cross-linked ultra-high-molecular weight polyethylene liner and ceramic femoral head in total hip arthroplasty: a prospective study at 5 years follow-up.Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes.Danger of frustrated sensors: Role of Toll-like receptors and NOD-like receptors in aseptic and septic inflammations around total hip replacements.The degree of peri-implant osteolysis induced by PEEK, CoCrMo, and HXLPE wear particles: a study based on a porous Ti6Al4V implant in a rabbit model.BMP-7 ameliorates cobalt alloy particle-induced inflammation by suppressing Th17 responses.Pro-osteoclastic in vitro effect of Polyethylene-like nanoparticles: Involvement in the pathogenesis of implant aseptic loosening.
P2860
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P2860
Endosomal damage and TLR2 mediated inflammasome activation by alkane particles in the generation of aseptic osteolysis.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Endosomal damage and TLR2 medi ...... eration of aseptic osteolysis.
@en
Endosomal damage and TLR2 medi ...... eration of aseptic osteolysis.
@nl
type
label
Endosomal damage and TLR2 medi ...... eration of aseptic osteolysis.
@en
Endosomal damage and TLR2 medi ...... eration of aseptic osteolysis.
@nl
prefLabel
Endosomal damage and TLR2 medi ...... eration of aseptic osteolysis.
@en
Endosomal damage and TLR2 medi ...... eration of aseptic osteolysis.
@nl
P2093
P2860
P1433
P1476
Endosomal damage and TLR2 medi ...... eration of aseptic osteolysis.
@en
P2093
Brian Scharf
Cristina C Clement
Daniel Paget
Giovanna M Crisi
Neil Cobelli
P Edward Purdue
Radhashree Maitra
Sriram Chitta
P2860
P304
P356
10.1016/J.MOLIMM.2009.09.023
P577
2009-10-04T00:00:00Z