Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology.
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Molecular docking as a popular tool in drug design, an in silico travelThe Trafficking of the Water Channel Aquaporin-2 in Renal Principal Cells-a Potential Target for Pharmacological Intervention in Cardiovascular DiseasesMarine natural products as breast cancer resistance protein inhibitorsMotif mediated protein-protein interactions as drug targetsOvercoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.MTiOpenScreen: a web server for structure-based virtual screening.Alternative modulation of protein-protein interactions by small moleculesDARC 2.0: Improved Docking and Virtual Screening at Protein Interaction SitesState-of-the-art strategies for targeting protein-protein interactions by small-molecule inhibitors.In silico identification of essential proteins in Corynebacterium pseudotuberculosis based on protein-protein interaction networksA Tryptoline Ring-Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine.Computational Tools for Allosteric Drug Discovery: Site Identification and Focus Library Design.iPPI-DB: an online database of modulators of protein-protein interactions.Flexibility and small pockets at protein-protein interfaces: New insights into druggability.Accessing external innovation in drug discovery and development.ProteinsPlus: a web portal for structure analysis of macromolecules.Computational analysis of calculated physicochemical and ADMET properties of protein-protein interaction inhibitorsComputational Biology and Chemistry in MTi: Emphasis on the Prediction of Some ADMET Properties.How an Inhibitor Bound to Subunit Interface Alters Triosephosphate Isomerase DynamicsA Synthetic Loop Replacement Peptide That Blocks Canonical NF-κB Signaling.In Silico Studies of Mammalian δ-ALAD Interactions with Selenides and Selenoxides.Tailored Approaches in Drug Development and Diagnostics: From Molecular Design to Biological Model Systems.Disrupting the PCSK9/LDLR protein-protein interaction by an imidazole-based minimalist peptidomimetic.Gly74Ser mutation in protein C causes thrombosis due to a defect in protein S-dependent anticoagulant function.Underlying mechanisms of cyclic peptide inhibitors interrupting the interaction of CK2α/CK2β: comparative molecular dynamics simulation studies.Inhibitors of DNA Methyltransferases From Natural Sources: A Computational Perspective
P2860
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P2860
Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
Drug-Like Protein-Protein Inte ...... iscovery and Chemical Biology.
@en
Drug-Like Protein-Protein Inte ...... iscovery and Chemical Biology.
@nl
type
label
Drug-Like Protein-Protein Inte ...... iscovery and Chemical Biology.
@en
Drug-Like Protein-Protein Inte ...... iscovery and Chemical Biology.
@nl
prefLabel
Drug-Like Protein-Protein Inte ...... iscovery and Chemical Biology.
@en
Drug-Like Protein-Protein Inte ...... iscovery and Chemical Biology.
@nl
P2093
P2860
P356
P1476
Drug-Like Protein-Protein Inte ...... iscovery and Chemical Biology.
@en
P2093
Bruno O Villoutreix
Céline Labbé
David Lagorce
Heriberto Bruzzoni-Giovanelli
Jean-Luc Poyet
Melaine A Kuenemann
P2860
P304
P356
10.1002/MINF.201400040
P577
2014-06-02T00:00:00Z