about
Dexamethasone-mediated up-regulation of human CYP2A6 involves the glucocorticoid receptor and increased binding of hepatic nuclear factor 4 alpha to the proximal promoterTargeting of nuclear factor-kappaB and proteasome by dithiocarbamate complexes with metalsKhellin and visnagin differentially modulate AHR signaling and downstream CYP1A activity in human liver cellsOmeprazole and lansoprazole enantiomers induce CYP3A4 in human hepatocytes and cell lines via glucocorticoid receptor and pregnane X receptor axisGold(I)-triphenylphosphine complexes with hypoxanthine-derived ligands: in vitro evaluations of anticancer and anti-inflammatory activitiesGold(I) complexes of 9-deazahypoxanthine as selective antitumor and anti-inflammatory agentsDual effects of ketoconazole cis-enantiomers on CYP3A4 in human hepatocytes and HepG2 CellsPotentiating effect of UVA irradiation on anticancer activity of Carboplatin derivatives involving 7-azaindolesOptical Isomers of Atorvastatin, Rosuvastatin and Fluvastatin Enantiospecifically Activate Pregnane X Receptor PXR and Induce CYP2A6, CYP2B6 and CYP3A4 in Human HepatocytesXenobiotic-induced transcriptional regulation of xenobiotic metabolizing enzymes of the cytochrome P450 superfamily in human extrahepatic tissuesRifampicin Does not Significantly Affect the Expression of Small Heterodimer Partner in Primary Human HepatocytesIn Vitro Antitumor Active Gold(I) Triphenylphosphane Complexes Containing 7-Azaindoles.Differential effects of omeprazole and lansoprazole enantiomers on aryl hydrocarbon receptor in human hepatocytes and cell lines.Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor.Pharmacological and molecular effects of platinum(II) complexes involving 7-azaindole derivatives.Novel stably transfected human reporter cell line AIZ-AR as a tool for an assessment of human androgen receptor transcriptional activity.Pathophysiological factors affecting CAR gene expression.Highly and Broad-Spectrum In Vitro Antitumor Active cis-Dichloridoplatinum(II) Complexes with 7-AzaindolesPlatinum(II) Iodido Complexes of 7-Azaindoles with Significant Antiproliferative Effects: An Old Story Revisited with Unexpected OutcomesMetabolism of sanguinarine: the facts and the myths.Investigation of the CYP2C9 induction profile in human hepatocytes by combining experimental and modelling approaches.Janus-faced Acrolein prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposureRegulation of drug-metabolizing cytochrome P450 enzymes by glucocorticoids.Endogenous and exogenous ligands of aryl hydrocarbon receptor: current state of art.Steroid regulation of drug-metabolizing cytochromes P450.The ubiquitin-proteasome system (UPS) and the mechanism of action of bortezomib.Intestinal cell-specific vitamin D receptor (VDR)-mediated transcriptional regulation of CYP3A4 gene.Triorganotin compounds--ligands for "rexinoid" inducible transcription factors: biological effects.Opportunities and challenges in using human hepatocytes in cytochromes P450 induction assays.Itraconazole cis-diastereoisomers activate aryl hydrocarbon receptor AhR and pregnane X receptor PXR and induce CYP1A1 in human cell lines and human hepatocytes.Half-Sandwich Ru(II) Halogenido, Valproato and 4-Phenylbutyrato Complexes Containing 2,2'-Dipyridylamine: Synthesis, Characterization, Solution Chemistry and In Vitro Cytotoxicity.Design and characterization of highly in vitro antitumor active ternary copper(II) complexes containing 2'-hydroxychalcone ligands.Optical isomers of dihydropyridine calcium channel blockers display enantiospecific effects on the expression and enzyme activities of human xenobiotics-metabolizing cytochromes P450.Assessment of the aryl hydrocarbon receptor-mediated activities of polycyclic aromatic hydrocarbons in a human cell-based reporter gene assay.Transplant drugs affect the expression of phase II and antioxidant enzymes in human carcinoma cells HepG2 but not in primary cultures of human hepatocytes: In vitro comparative study.Platinum(II) carboxylato complexes containing 7-azaindoles as N-donor carrier ligands showed cytotoxicity against cancer cell lines.Profiling of Vitamin D Metabolic Intermediates toward VDR Using Novel Stable Gene Reporter Cell Lines IZ-VDRE and IZ-CYP24.Pleiotropic effects of gold(I) mixed-ligand complexes of 9-deazahypoxanthine on transcriptional activity of receptors for steroid hormones, nuclear receptors and xenoreceptors in human hepatocytes and cell lines.Mixed-ligand copper(II) complexes activate aryl hydrocarbon receptor AhR and induce CYP1A genes expression in human hepatocytes and human cell lines.Development and Characterization of a Human Reporter Cell Line for the Assessment of Thyroid Receptor Transcriptional Activity: A Case of Organotin Endocrine Disruptors.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Zdenek Dvorak
@ast
Zdenek Dvorak
@en
Zdenek Dvorak
@es
Zdenek Dvorak
@nl
Zdenek Dvorak
@sl
type
label
Zdenek Dvorak
@ast
Zdenek Dvorak
@en
Zdenek Dvorak
@es
Zdenek Dvorak
@nl
Zdenek Dvorak
@sl
prefLabel
Zdenek Dvorak
@ast
Zdenek Dvorak
@en
Zdenek Dvorak
@es
Zdenek Dvorak
@nl
Zdenek Dvorak
@sl
P106
P1153
44861288800
P21
P31
P496
0000-0002-3938-3585