about
Endochin-like quinolones are highly efficacious against acute and latent experimental toxoplasmosisHost cell manipulation by the human pathogen Toxoplasma gondiiEffects of Toxoplasma gondii infection on the brainRecent insights into apicomplexan parasite egress provide new views to a killA novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite divisionToxoplasma MIC2 is a major determinant of invasion and virulenceToxoplasma gondii Cathepsin L Is the Primary Target of the Invasion-inhibitory Compound Morpholinurea-leucyl-homophenyl-vinyl Sulfone PhenylMicroneme Protein 5 Regulates the Activity of Toxoplasma Subtilisin 1 by Mimicking a Subtilisin ProdomainEctopic expression of a Neospora caninum Kazal type inhibitor triggers developmental defects in Toxoplasma and PlasmodiumTagging of endogenous genes in a Toxoplasma gondii strain lacking Ku80A conserved apicomplexan microneme protein contributes to Toxoplasma gondii invasion and virulenceMicrobial pathogenesis: mechanisms of infectious disease.Rapid membrane disruption by a perforin-like protein facilitates parasite exit from host cells.Toxoplasma gondii protease TgSUB1 is required for cell surface processing of micronemal adhesive complexes and efficient adhesion of tachyzoites.A dynamin is required for the biogenesis of secretory organelles in Toxoplasma gondiiCharacterization of the chloroquine resistance transporter homologue in Toxoplasma gondiiMolecular characterization of TgMIC5, a proteolytically processed antigen secreted from the micronemes of Toxoplasma gondii.Translocation of ribosomal protein P0 onto the Toxoplasma gondii tachyzoite surface.Proteomic analysis of cleavage events reveals a dynamic two-step mechanism for proteolysis of a key parasite adhesive complex.The Toxoplasma homolog of Plasmodium apical membrane antigen-1 (AMA-1) is a microneme protein secreted in response to elevated intracellular calcium levels.Analysis of the Sarcocystis neurona microneme protein SnMIC10: protein characteristics and expression during intracellular development.The opportunistic pathogen Toxoplasma gondii deploys a diverse legion of invasion and survival proteinsToxoplasma gondii uses sulfated proteoglycans for substrate and host cell attachment.Cathepsin L occupies a vacuolar compartment and is a protein maturase within the endo/exocytic system of Toxoplasma gondii.Toxoplasma gondii ingests and digests host cytosolic proteins.Armed and dangerous: Toxoplasma gondii uses an arsenal of secretory proteins to infect host cells.Host cell invasion by the opportunistic pathogen Toxoplasma gondii.Is Toxoplasma egress the first step in invasion?Toxoplasma gondii toxolysin 4 is an extensively processed putative metalloproteinase secreted from micronemesA novel high throughput invasion screen identifies host actin regulators required for efficient cell entry by Toxoplasma gondii.Cell cycle-dependent, intercellular transmission of Toxoplasma gondii is accompanied by marked changes in parasite gene expression.Rapid invasion of host cells by Toxoplasma requires secretion of the MIC2-M2AP adhesive protein complex.Protein trafficking through the endosomal system prepares intracellular parasites for a home invasionForward targeting of Toxoplasma gondii proproteins to the micronemes involves conserved aliphatic amino acids.Toxoplasma gondii-induced activation of EGFR prevents autophagy protein-mediated killing of the parasite.Structural basis of Toxoplasma gondii MIC2-associated protein interaction with MIC2A cleavable propeptide influences Toxoplasma infection by facilitating the trafficking and secretion of the TgMIC2-M2AP invasion complexAcidification Activates Toxoplasma gondii Motility and Egress by Enhancing Protein Secretion and Cytolytic ActivityCysteine protease inhibitors block Toxoplasma gondii microneme secretion and cell invasionTargeted disruption of Toxoplasma gondii serine protease inhibitor 1 increases bradyzoite cyst formation in vitro and parasite tissue burden in mice.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Vern Carruthers
@ast
Vern Carruthers
@en
Vern Carruthers
@es
Vern Carruthers
@nl
Vern Carruthers
@sl
type
label
Vern Carruthers
@ast
Vern Carruthers
@en
Vern Carruthers
@es
Vern Carruthers
@nl
Vern Carruthers
@sl
prefLabel
Vern Carruthers
@ast
Vern Carruthers
@en
Vern Carruthers
@es
Vern Carruthers
@nl
Vern Carruthers
@sl
P106
P1153
7003507957
P21
P31
P496
0000-0001-6859-8895