The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML. - Wikidata - awgldk - TriplyDB

The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.

The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.

http://www.wikidata.org/entity/Q42723875

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Aberrant Wnt Signaling in Leukemia Cancer of the Pancreas: Molecular Pathways and Current Advancement in Treatment Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis-Masters of Survival and Clonality?Renal Cancer Stem Cells: Characterization and Targeted Therapies Targeting leukemia stem cells: which pathways drive self-renewal activity in T-cell acute lymphoblastic leukemia?Current approaches in identification and isolation of human renal cell carcinoma cancer stem cells Chemical Disruption of Wnt-dependent Cell Fate Decision-making Mechanisms in Cancer and Regenerative Medicine Cancer stem cells--important players in tumor therapy resistance G Protein-Coupled Receptor Signaling in Stem Cells and Cancer Recent progress toward epigenetic therapies: the example of mixed lineage leukemia Advances in understanding the leukaemia microenvironment Wnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia development A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer Role of Microenvironment in Resistance to Therapy in AML The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma.Update on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunities Survival regulation of leukemia stem cells SALL4, the missing link between stem cells, development and cancer Reactive oxygen species mediate Cr(VI)-induced carcinogenesis through PI3K/AKT-dependent activation of GSK-3β/β-catenin signaling Altered Expression of Genes in Signaling Pathways Regulating Proliferation of Hematopoietic Stem and Progenitor Cells in Mice with Subchronic Benzene Exposure Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signaling Sulindac sulfide reverses aberrant self-renewal of progenitor cells induced by the AML-associated fusion proteins PML/RARα and PLZF/RARα Intronless WNT10B-short variant underlies new recurrent allele-specific rearrangement in acute myeloid leukaemia β-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroids The Risa R/Bioconductor package: integrative data analysis from experimental metadata and back again.Integrative analysis of copy number and gene expression data suggests novel pathogenetic mechanisms in primary myelofibrosis.Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia β-catenin and PI3Kδ inhibition expands precursor Th17 cells with heightened stemness and antitumor activity.Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells.Chromatin modifications as therapeutic targets in MLL-rearranged leukemia.Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemia β-catenin induces expression of prohibitin gene in acute leukemic cells Tissue transglutaminase regulates β-catenin signaling through a c-Src-dependent mechanism.Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma.Role of EZH2 in cancer stem cells: from biological insight to a therapeutic target.Cancer stem cells: a stride towards cancer cure?Inhibiting CCN1 blocks AML cell growth by disrupting the MEK/ERK pathway.The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.CD44 targets Wnt/β-catenin pathway to mediate the proliferation of K562 cells Wnt signaling in cancer

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The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.

http://www.wikidata.org/entity/Q42723875

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The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML.

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The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML.

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The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML.

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The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML.

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The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML.

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The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML.

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The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML

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Amit U Sinha

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Andrei V Krivtsov

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Leonard I Zon

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Scott A Armstrong

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Trista E North

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Zhaohui Feng

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P2860

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

A role for Wnt signalling in self-renewal of haematopoietic stem cells

Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

Cancer stem cell-directed therapies: recent data from the laboratory and clinic.

Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b.

Wnt-related molecules and signaling pathway equilibrium in hematopoiesis.

Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors.

Hox genes: from leukemia to hematopoietic stem cell expansion.

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327

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