The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.
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Aberrant Wnt Signaling in LeukemiaCancer of the Pancreas: Molecular Pathways and Current Advancement in TreatmentMesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis-Masters of Survival and Clonality?Renal Cancer Stem Cells: Characterization and Targeted TherapiesTargeting leukemia stem cells: which pathways drive self-renewal activity in T-cell acute lymphoblastic leukemia?Current approaches in identification and isolation of human renal cell carcinoma cancer stem cellsChemical Disruption of Wnt-dependent Cell Fate Decision-making Mechanisms in Cancer and Regenerative MedicineCancer stem cells--important players in tumor therapy resistanceG Protein-Coupled Receptor Signaling in Stem Cells and CancerRecent progress toward epigenetic therapies: the example of mixed lineage leukemiaAdvances in understanding the leukaemia microenvironmentWnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia developmentA new prospect in cancer therapy: targeting cancer stem cells to eradicate cancerRole of Microenvironment in Resistance to Therapy in AMLThe EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma.Update on acute myeloid leukemia stem cells: New discoveries and therapeutic opportunitiesSurvival regulation of leukemia stem cellsSALL4, the missing link between stem cells, development and cancerReactive oxygen species mediate Cr(VI)-induced carcinogenesis through PI3K/AKT-dependent activation of GSK-3β/β-catenin signalingAltered Expression of Genes in Signaling Pathways Regulating Proliferation of Hematopoietic Stem and Progenitor Cells in Mice with Subchronic Benzene ExposureCadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signalingSulindac sulfide reverses aberrant self-renewal of progenitor cells induced by the AML-associated fusion proteins PML/RARα and PLZF/RARαIntronless WNT10B-short variant underlies new recurrent allele-specific rearrangement in acute myeloid leukaemiaβ-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroidsThe Risa R/Bioconductor package: integrative data analysis from experimental metadata and back again.Integrative analysis of copy number and gene expression data suggests novel pathogenetic mechanisms in primary myelofibrosis.Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemiaβ-catenin and PI3Kδ inhibition expands precursor Th17 cells with heightened stemness and antitumor activity.Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells.Chromatin modifications as therapeutic targets in MLL-rearranged leukemia.Sox4 is a key oncogenic target in C/EBPα mutant acute myeloid leukemiaβ-catenin induces expression of prohibitin gene in acute leukemic cellsTissue transglutaminase regulates β-catenin signaling through a c-Src-dependent mechanism.Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma.Role of EZH2 in cancer stem cells: from biological insight to a therapeutic target.Cancer stem cells: a stride towards cancer cure?Inhibiting CCN1 blocks AML cell growth by disrupting the MEK/ERK pathway.The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia.CD44 targets Wnt/β-catenin pathway to mediate the proliferation of K562 cellsWnt signaling in cancer
P2860
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P2860
The Wnt/beta-catenin pathway is required for the development of leukemia stem cells in AML.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML.
@en
The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML.
@nl
type
label
The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML.
@en
The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML.
@nl
prefLabel
The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML.
@en
The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML.
@nl
P2093
P2860
P356
P1433
P1476
The Wnt/beta-catenin pathway i ...... of leukemia stem cells in AML
@en
P2093
Amit U Sinha
Andrei V Krivtsov
Leonard I Zon
Scott A Armstrong
Trista E North
Zhaohui Feng
P2860
P304
P356
10.1126/SCIENCE.1186624
P407
P577
2010-03-01T00:00:00Z