Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults. - Wikidata - awgldk - TriplyDB

Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults.

Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults.

http://www.wikidata.org/entity/Q42727069

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Neuroprotective Transcription Factors in Animal Models of Parkinson Disease Mouse models of Parkinson's disease associated with mitochondrial dysfunction Maintenance of postmitotic neuronal cell identity Investigation of Homeodomain Membrane Translocation Properties: Insights from the Structure Determination of Engrailed-2 Homeodomain in Aqueous and Membrane-Mimetic Environments Insights into the post-transcriptional regulation of the mitochondrial electron transport chain A transducible nuclear/nucleolar protein, mLLP, regulates neuronal morphogenesis and synaptic transmission Trichostatin A targets the mitochondrial respiratory chain, increasing mitochondrial reactive oxygen species production to trigger apoptosis in human breast cancer cells Depletion of canonical Wnt signaling components has a neuroprotective effect on midbrain dopaminergic neurons in an MPTP-induced mouse model of Parkinson's disease Choroid-plexus-derived Otx2 homeoprotein constrains adult cortical plasticity Progressive nigrostriatal terminal dysfunction and degeneration in the engrailed1 heterozygous mouse model of Parkinson's disease Kearns-Sayre syndrome: a case series of 35 adults and children Postnatal signalling with homeoprotein transcription factors Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function.Local translation of extranuclear lamin B promotes axon maintenance Engrailed-2 (En2) deletion produces multiple neurodevelopmental defects in monoamine systems, forebrain structures and neurogenesis and behavior Identification of Multiple QTLs Linked to Neuropathology in the Engrailed-1 Heterozygous Mouse Model of Parkinson's Disease.Mouse models of mitochondrial complex I dysfunction Engrailed is required in maturing serotonin neurons to regulate the cytoarchitecture and survival of the dorsal raphe nucleus.Homeoprotein signaling in the developing and adult nervous system.Signaling with homeoprotein transcription factors in development and throughout adulthood.Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair.Engrailed signaling in axon guidance and neuron survival.Cellular programming and reprogramming: sculpting cell fate for the production of dopamine neurons for cell therapy.Axonal transcription factors: novel regulators of growth cone-to-nucleus signaling.The lifelong maintenance of mesencephalic dopaminergic neurons by Nurr1 and engrailed Molecular mechanisms of dopaminergic subset specification: fundamental aspects and clinical perspectives.Transcriptome profiling in engrailed-2 mutant mice reveals common molecular pathways associated with autism spectrum disorders.Dissecting the role of Engrailed in adult dopaminergic neurons--Insights into Parkinson disease pathogenesis Sensitizing basal-like breast cancer to chemotherapy using nanoparticles conjugated with interference peptide.Is Axonal Degeneration a Key Early Event in Parkinson's Disease?Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress Local homeoprotein diffusion can stabilize boundaries generated by graded positional cues.Molecular Programming of Mesodiencephalic Dopaminergic Neuronal Subsets.Increased signaling by the autism-related Engrailed-2 protein enhances dendritic branching and spine density, alters synaptic structural matching, and exaggerates protein synthesis.Axonal mRNA translation: an unexpected link to axon survival and the mitochondrion.Role of estrogen receptor beta in neural differentiation of mouse embryonic stem cells.Engrailed 1 overexpression as a potential prognostic marker in quintuple-negative breast cancer.Transcription Factors: Potential Cell Death Markers in Parkinson's Disease.A novel floor plate boundary defined by adjacent En1 and Dbx1 microdomains distinguishes midbrain dopamine and hypothalamic neurons.Regulation of complex I by Engrailed is complex too.

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P2860

Engrailed protects mouse midbrain dopaminergic neurons against mitochondrial complex I insults.

http://www.wikidata.org/entity/Q42727069

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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2011年论文

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name

Engrailed protects mouse midbr ...... tochondrial complex I insults.

@en

Engrailed protects mouse midbr ...... tochondrial complex I insults.

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type

label

Engrailed protects mouse midbr ...... tochondrial complex I insults.

@en

Engrailed protects mouse midbr ...... tochondrial complex I insults.

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prefLabel

Engrailed protects mouse midbr ...... tochondrial complex I insults.

@en

Engrailed protects mouse midbr ...... tochondrial complex I insults.

@nl

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Nature Neuroscience

P1476

Engrailed protects mouse midbr ...... tochondrial complex I insults.

@en

P2093

Alain Prochiantz

http://www.w3.org/2001/XMLSchema#string

Andreas Hartmann

http://www.w3.org/2001/XMLSchema#string

Anne Lombès

http://www.w3.org/2001/XMLSchema#string

Colette Bouillot

http://www.w3.org/2001/XMLSchema#string

Daniel Alvarez-Fischer

http://www.w3.org/2001/XMLSchema#string

Kenneth L Moya

http://www.w3.org/2001/XMLSchema#string

Olivia Massiani-Beaudoin

http://www.w3.org/2001/XMLSchema#string

Olivier Stettler

http://www.w3.org/2001/XMLSchema#string

Rajiv L Joshi

http://www.w3.org/2001/XMLSchema#string

P2860

The transcription factor Engrailed-2 guides retinal axons

Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain

Emx2 homeodomain transcription factor interacts with eukaryotic translation initiation factor 4E (eIF4E) in the axons of olfactory sensory neurons

Dysfunctions of cellular oxidative metabolism in patients with mutations in the NDUFS1 and NDUFS4 genes of complex I

Mutant NDUFS3 subunit of mitochondrial complex I causes Leigh syndrome

Rescue of mesencephalic dopaminergic neurons in culture by low-level stimulation of voltage-gated sodium channels

The transcription factor PITX3 is associated with sporadic Parkinson's disease

Role of axonal transport in neurodegenerative diseases

Progressive loss of dopaminergic neurons in the ventral midbrain of adult mice heterozygote for Engrailed1

Rescue of the En-1 mutant phenotype by replacement of En-1 with En-2

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P304

1260-1266

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scholarly article

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10.1038/NN.2916

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P433

10

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14

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Wolfgang H. Oertel

Wolfgang Faigle

François Castagner

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2011-09-04T00:00:00Z

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51618542

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1026652675

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21892157

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